9L6E
A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008424 | molecular_function | glycoprotein 6-alpha-L-fucosyltransferase activity |
| A | 0009101 | biological_process | glycoprotein biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0032580 | cellular_component | Golgi cisterna membrane |
| B | 0008424 | molecular_function | glycoprotein 6-alpha-L-fucosyltransferase activity |
| B | 0009101 | biological_process | glycoprotein biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0032580 | cellular_component | Golgi cisterna membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 122 |
| Details | Domain: {"description":"SH3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00192","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Region: {"description":"Important for donor substrate binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Motif: {"description":"SH3-binding","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9WTS2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
