9KOM

Cryo-EM structure of human pannexin-3 protomer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001649	biological_process	osteoblast differentiation
A	0005198	molecular_function	structural molecule activity
A	0005262	molecular_function	calcium channel activity
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005886	cellular_component	plasma membrane
A	0005921	cellular_component	gap junction
A	0006811	biological_process	monoatomic ion transport
A	0006812	biological_process	monoatomic cation transport
A	0007267	biological_process	cell-cell signaling
A	0015267	molecular_function	channel activity
A	0022829	molecular_function	wide pore channel activity
A	0032732	biological_process	positive regulation of interleukin-1 production
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0055077	molecular_function	gap junction hemi-channel activity
A	0070588	biological_process	calcium ion transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00351","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	30
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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