9KMP

CRP-HCAb1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001849	molecular_function	complement component C1q complex binding
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006953	biological_process	acute-phase response
A	0006954	biological_process	inflammatory response
A	0008228	biological_process	opsonization
A	0010628	biological_process	positive regulation of gene expression
A	0010745	biological_process	negative regulation of macrophage derived foam cell differentiation
A	0010888	biological_process	negative regulation of lipid storage
A	0030169	molecular_function	low-density lipoprotein particle binding
A	0032677	biological_process	regulation of interleukin-8 production
A	0032930	biological_process	positive regulation of superoxide anion generation
A	0032945	biological_process	negative regulation of mononuclear cell proliferation
A	0033265	molecular_function	choline binding
A	0042310	biological_process	vasoconstriction
A	0042802	molecular_function	identical protein binding
A	0045087	biological_process	innate immune response
A	0046790	molecular_function	virion binding
A	0046872	molecular_function	metal ion binding
A	0050750	molecular_function	low-density lipoprotein particle receptor binding
A	0050830	biological_process	defense response to Gram-positive bacterium
C	0001849	molecular_function	complement component C1q complex binding
C	0005509	molecular_function	calcium ion binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0006953	biological_process	acute-phase response
C	0006954	biological_process	inflammatory response
C	0008228	biological_process	opsonization
C	0010628	biological_process	positive regulation of gene expression
C	0010745	biological_process	negative regulation of macrophage derived foam cell differentiation
C	0010888	biological_process	negative regulation of lipid storage
C	0030169	molecular_function	low-density lipoprotein particle binding
C	0032677	biological_process	regulation of interleukin-8 production
C	0032930	biological_process	positive regulation of superoxide anion generation
C	0032945	biological_process	negative regulation of mononuclear cell proliferation
C	0033265	molecular_function	choline binding
C	0042310	biological_process	vasoconstriction
C	0042802	molecular_function	identical protein binding
C	0045087	biological_process	innate immune response
C	0046790	molecular_function	virion binding
C	0046872	molecular_function	metal ion binding
C	0050750	molecular_function	low-density lipoprotein particle receptor binding
C	0050830	biological_process	defense response to Gram-positive bacterium
E	0001849	molecular_function	complement component C1q complex binding
E	0005509	molecular_function	calcium ion binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0006953	biological_process	acute-phase response
E	0006954	biological_process	inflammatory response
E	0008228	biological_process	opsonization
E	0010628	biological_process	positive regulation of gene expression
E	0010745	biological_process	negative regulation of macrophage derived foam cell differentiation
E	0010888	biological_process	negative regulation of lipid storage
E	0030169	molecular_function	low-density lipoprotein particle binding
E	0032677	biological_process	regulation of interleukin-8 production
E	0032930	biological_process	positive regulation of superoxide anion generation
E	0032945	biological_process	negative regulation of mononuclear cell proliferation
E	0033265	molecular_function	choline binding
E	0042310	biological_process	vasoconstriction
E	0042802	molecular_function	identical protein binding
E	0045087	biological_process	innate immune response
E	0046790	molecular_function	virion binding
E	0046872	molecular_function	metal ion binding
E	0050750	molecular_function	low-density lipoprotein particle receptor binding
E	0050830	biological_process	defense response to Gram-positive bacterium
G	0001849	molecular_function	complement component C1q complex binding
G	0005509	molecular_function	calcium ion binding
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005615	cellular_component	extracellular space
G	0006953	biological_process	acute-phase response
G	0006954	biological_process	inflammatory response
G	0008228	biological_process	opsonization
G	0010628	biological_process	positive regulation of gene expression
G	0010745	biological_process	negative regulation of macrophage derived foam cell differentiation
G	0010888	biological_process	negative regulation of lipid storage
G	0030169	molecular_function	low-density lipoprotein particle binding
G	0032677	biological_process	regulation of interleukin-8 production
G	0032930	biological_process	positive regulation of superoxide anion generation
G	0032945	biological_process	negative regulation of mononuclear cell proliferation
G	0033265	molecular_function	choline binding
G	0042310	biological_process	vasoconstriction
G	0042802	molecular_function	identical protein binding
G	0045087	biological_process	innate immune response
G	0046790	molecular_function	virion binding
G	0046872	molecular_function	metal ion binding
G	0050750	molecular_function	low-density lipoprotein particle receptor binding
G	0050830	biological_process	defense response to Gram-positive bacterium
H	0001849	molecular_function	complement component C1q complex binding
H	0005509	molecular_function	calcium ion binding
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005615	cellular_component	extracellular space
H	0006953	biological_process	acute-phase response
H	0006954	biological_process	inflammatory response
H	0008228	biological_process	opsonization
H	0010628	biological_process	positive regulation of gene expression
H	0010745	biological_process	negative regulation of macrophage derived foam cell differentiation
H	0010888	biological_process	negative regulation of lipid storage
H	0030169	molecular_function	low-density lipoprotein particle binding
H	0032677	biological_process	regulation of interleukin-8 production
H	0032930	biological_process	positive regulation of superoxide anion generation
H	0032945	biological_process	negative regulation of mononuclear cell proliferation
H	0033265	molecular_function	choline binding
H	0042310	biological_process	vasoconstriction
H	0042802	molecular_function	identical protein binding
H	0045087	biological_process	innate immune response
H	0046790	molecular_function	virion binding
H	0046872	molecular_function	metal ion binding
H	0050750	molecular_function	low-density lipoprotein particle receptor binding
H	0050830	biological_process	defense response to Gram-positive bacterium

Functional Information from PROSITE/UniProt

site_id	PS00289
Number of Residues	8
Details	PTX_1 Pentraxin domain signature. HiCtSWeS

Chain	Residue	Details
A	HIS95-SER102

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1005
Details	Domain: {"description":"Pentraxin (PTX)","evidences":[{"source":"PROSITE-ProRule","id":"PRU01172","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	30
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01172","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	5
Details	Modified residue: {"description":"Pyrrolidone carboxylic acid","evidences":[{"source":"PubMed","id":"762075","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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