9KMB

Crystal structure of human glutaminyl cyclase in complex with N-(2-(1H-imidazol-5-yl)ethyl)-4-methoxybenzenesulfonamide

This is a non-PDB format compatible entry.

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"18072935","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16135565","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18072935","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21288892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21671571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AFO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZED","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZEP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PBB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PBE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YWY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"21671571","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---