9KAY

Bioengineered protein nanocarrier facilitating siRNA escape from lysosomes for targeted RNAi therapy in glioblastoma

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Aa	0006826	biological_process	iron ion transport
Aa	0006879	biological_process	intracellular iron ion homeostasis
Aa	0008199	molecular_function	ferric iron binding
Ab	0006826	biological_process	iron ion transport
Ab	0006879	biological_process	intracellular iron ion homeostasis
Ab	0008199	molecular_function	ferric iron binding
Ac	0006826	biological_process	iron ion transport
Ac	0006879	biological_process	intracellular iron ion homeostasis
Ac	0008199	molecular_function	ferric iron binding
Ad	0006826	biological_process	iron ion transport
Ad	0006879	biological_process	intracellular iron ion homeostasis
Ad	0008199	molecular_function	ferric iron binding
Ae	0006826	biological_process	iron ion transport
Ae	0006879	biological_process	intracellular iron ion homeostasis
Ae	0008199	molecular_function	ferric iron binding
Af	0006826	biological_process	iron ion transport
Af	0006879	biological_process	intracellular iron ion homeostasis
Af	0008199	molecular_function	ferric iron binding
Ag	0006826	biological_process	iron ion transport
Ag	0006879	biological_process	intracellular iron ion homeostasis
Ag	0008199	molecular_function	ferric iron binding
Ah	0006826	biological_process	iron ion transport
Ah	0006879	biological_process	intracellular iron ion homeostasis
Ah	0008199	molecular_function	ferric iron binding
Ai	0006826	biological_process	iron ion transport
Ai	0006879	biological_process	intracellular iron ion homeostasis
Ai	0008199	molecular_function	ferric iron binding
Aj	0006826	biological_process	iron ion transport
Aj	0006879	biological_process	intracellular iron ion homeostasis
Aj	0008199	molecular_function	ferric iron binding
Ak	0006826	biological_process	iron ion transport
Ak	0006879	biological_process	intracellular iron ion homeostasis
Ak	0008199	molecular_function	ferric iron binding
Al	0006826	biological_process	iron ion transport
Al	0006879	biological_process	intracellular iron ion homeostasis
Al	0008199	molecular_function	ferric iron binding
Am	0006826	biological_process	iron ion transport
Am	0006879	biological_process	intracellular iron ion homeostasis
Am	0008199	molecular_function	ferric iron binding
An	0006826	biological_process	iron ion transport
An	0006879	biological_process	intracellular iron ion homeostasis
An	0008199	molecular_function	ferric iron binding
Ao	0006826	biological_process	iron ion transport
Ao	0006879	biological_process	intracellular iron ion homeostasis
Ao	0008199	molecular_function	ferric iron binding
Ap	0006826	biological_process	iron ion transport
Ap	0006879	biological_process	intracellular iron ion homeostasis
Ap	0008199	molecular_function	ferric iron binding
Aq	0006826	biological_process	iron ion transport
Aq	0006879	biological_process	intracellular iron ion homeostasis
Aq	0008199	molecular_function	ferric iron binding
Ar	0006826	biological_process	iron ion transport
Ar	0006879	biological_process	intracellular iron ion homeostasis
Ar	0008199	molecular_function	ferric iron binding
As	0006826	biological_process	iron ion transport
As	0006879	biological_process	intracellular iron ion homeostasis
As	0008199	molecular_function	ferric iron binding
At	0006826	biological_process	iron ion transport
At	0006879	biological_process	intracellular iron ion homeostasis
At	0008199	molecular_function	ferric iron binding
Au	0006826	biological_process	iron ion transport
Au	0006879	biological_process	intracellular iron ion homeostasis
Au	0008199	molecular_function	ferric iron binding
Av	0006826	biological_process	iron ion transport
Av	0006879	biological_process	intracellular iron ion homeostasis
Av	0008199	molecular_function	ferric iron binding
Aw	0006826	biological_process	iron ion transport
Aw	0006879	biological_process	intracellular iron ion homeostasis
Aw	0008199	molecular_function	ferric iron binding
Ax	0006826	biological_process	iron ion transport
Ax	0006879	biological_process	intracellular iron ion homeostasis
Ax	0008199	molecular_function	ferric iron binding

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFIEthYLnkqvkaIK

Chain	Residue	Details
Aa	ASP126-LYS146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"PubMed","id":"1992356","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FHA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Site: {"description":"Essential for association with cargo receptor NCOA4","evidences":[{"source":"PubMed","id":"26436293","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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