9K5E

Structure of substrate-engaged double-cap human proteasome in state EA1-EA1

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Aa	0000502	cellular_component	proteasome complex
Aa	0005198	molecular_function	structural molecule activity
Aa	0005515	molecular_function	protein binding
Aa	0005576	cellular_component	extracellular region
Aa	0005634	cellular_component	nucleus
Aa	0005654	cellular_component	nucleoplasm
Aa	0005829	cellular_component	cytosol
Aa	0005838	cellular_component	proteasome regulatory particle
Aa	0006511	biological_process	ubiquitin-dependent protein catabolic process
Aa	0006979	biological_process	response to oxidative stress
Aa	0008021	cellular_component	synaptic vesicle
Aa	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
Aa	0010498	biological_process	proteasomal protein catabolic process
Aa	0016020	cellular_component	membrane
Aa	0022624	cellular_component	proteasome accessory complex
Aa	0034774	cellular_component	secretory granule lumen
Aa	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Aa	0061136	biological_process	regulation of proteasomal protein catabolic process
Aa	0071357	biological_process	cellular response to type I interferon
Aa	1904813	cellular_component	ficolin-1-rich granule lumen
AA	0000502	cellular_component	proteasome complex
AA	0000932	cellular_component	P-body
AA	0001649	biological_process	osteoblast differentiation
AA	0005515	molecular_function	protein binding
AA	0005576	cellular_component	extracellular region
AA	0005634	cellular_component	nucleus
AA	0005654	cellular_component	nucleoplasm
AA	0005737	cellular_component	cytoplasm
AA	0005829	cellular_component	cytosol
AA	0006511	biological_process	ubiquitin-dependent protein catabolic process
AA	0006979	biological_process	response to oxidative stress
AA	0008021	cellular_component	synaptic vesicle
AA	0010498	biological_process	proteasomal protein catabolic process
AA	0016020	cellular_component	membrane
AA	0022624	cellular_component	proteasome accessory complex
AA	0034774	cellular_component	secretory granule lumen
AA	0036402	molecular_function	proteasome-activating activity
AA	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
AA	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AA	0061136	biological_process	regulation of proteasomal protein catabolic process
AA	0071357	biological_process	cellular response to type I interferon
AA	1901800	biological_process	positive regulation of proteasomal protein catabolic process
AA	1904813	cellular_component	ficolin-1-rich granule lumen
Ab	0000502	cellular_component	proteasome complex
Ab	0003723	molecular_function	RNA binding
Ab	0005515	molecular_function	protein binding
Ab	0005634	cellular_component	nucleus
Ab	0005829	cellular_component	cytosol
Ab	0006979	biological_process	response to oxidative stress
Ab	0008021	cellular_component	synaptic vesicle
Ab	0010498	biological_process	proteasomal protein catabolic process
Ab	0022624	cellular_component	proteasome accessory complex
Ab	0042802	molecular_function	identical protein binding
Ab	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Ab	0060090	molecular_function	molecular adaptor activity
Ab	0061136	biological_process	regulation of proteasomal protein catabolic process
Ab	0071357	biological_process	cellular response to type I interferon
AB	0000502	cellular_component	proteasome complex
AB	0003723	molecular_function	RNA binding
AB	0005515	molecular_function	protein binding
AB	0005634	cellular_component	nucleus
AB	0005654	cellular_component	nucleoplasm
AB	0005737	cellular_component	cytoplasm
AB	0005829	cellular_component	cytosol
AB	0005838	cellular_component	proteasome regulatory particle
AB	0006979	biological_process	response to oxidative stress
AB	0008021	cellular_component	synaptic vesicle
AB	0010498	biological_process	proteasomal protein catabolic process
AB	0016020	cellular_component	membrane
AB	0022624	cellular_component	proteasome accessory complex
AB	0036402	molecular_function	proteasome-activating activity
AB	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AB	0061136	biological_process	regulation of proteasomal protein catabolic process
AB	0071357	biological_process	cellular response to type I interferon
Ac	0000502	cellular_component	proteasome complex
Ac	0000724	biological_process	double-strand break repair via homologous recombination
Ac	0004843	molecular_function	cysteine-type deubiquitinase activity
Ac	0005515	molecular_function	protein binding
Ac	0005576	cellular_component	extracellular region
Ac	0005634	cellular_component	nucleus
Ac	0005654	cellular_component	nucleoplasm
Ac	0005829	cellular_component	cytosol
Ac	0006303	biological_process	double-strand break repair via nonhomologous end joining
Ac	0006511	biological_process	ubiquitin-dependent protein catabolic process
Ac	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Ac	0006979	biological_process	response to oxidative stress
Ac	0008021	cellular_component	synaptic vesicle
Ac	0008237	molecular_function	metallopeptidase activity
Ac	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
Ac	0010498	biological_process	proteasomal protein catabolic process
Ac	0016241	biological_process	regulation of macroautophagy
Ac	0016579	biological_process	protein deubiquitination
Ac	0022624	cellular_component	proteasome accessory complex
Ac	0031597	cellular_component	cytosolic proteasome complex
Ac	0034774	cellular_component	secretory granule lumen
Ac	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Ac	0045471	biological_process	response to ethanol
Ac	0061133	molecular_function	endopeptidase activator activity
Ac	0061136	biological_process	regulation of proteasomal protein catabolic process
Ac	0061578	molecular_function	K63-linked deubiquitinase activity
Ac	0070536	biological_process	protein K63-linked deubiquitination
Ac	0070628	molecular_function	proteasome binding
Ac	0071357	biological_process	cellular response to type I interferon
Ac	0140492	molecular_function	metal-dependent deubiquitinase activity
Ac	1904813	cellular_component	ficolin-1-rich granule lumen
AC	0000502	cellular_component	proteasome complex
AC	0005102	molecular_function	signaling receptor binding
AC	0005515	molecular_function	protein binding
AC	0005634	cellular_component	nucleus
AC	0005654	cellular_component	nucleoplasm
AC	0005737	cellular_component	cytoplasm
AC	0005829	cellular_component	cytosol
AC	0005838	cellular_component	proteasome regulatory particle
AC	0005886	cellular_component	plasma membrane
AC	0006357	biological_process	regulation of transcription by RNA polymerase II
AC	0006979	biological_process	response to oxidative stress
AC	0008021	cellular_component	synaptic vesicle
AC	0008134	molecular_function	transcription factor binding
AC	0010498	biological_process	proteasomal protein catabolic process
AC	0016020	cellular_component	membrane
AC	0016234	cellular_component	inclusion body
AC	0016887	molecular_function	ATP hydrolysis activity
AC	0017025	molecular_function	TBP-class protein binding
AC	0022624	cellular_component	proteasome accessory complex
AC	0031410	cellular_component	cytoplasmic vesicle
AC	0031531	molecular_function	thyrotropin-releasing hormone receptor binding
AC	0031595	cellular_component	nuclear proteasome complex
AC	0031597	cellular_component	cytosolic proteasome complex
AC	0036402	molecular_function	proteasome-activating activity
AC	0043069	biological_process	negative regulation of programmed cell death
AC	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AC	0045893	biological_process	positive regulation of DNA-templated transcription
AC	0061136	biological_process	regulation of proteasomal protein catabolic process
AC	0070062	cellular_component	extracellular exosome
AC	0071357	biological_process	cellular response to type I interferon
AC	0072562	cellular_component	blood microparticle
AC	0090261	biological_process	positive regulation of inclusion body assembly
AC	0140296	molecular_function	general transcription initiation factor binding
AC	0140297	molecular_function	DNA-binding transcription factor binding
AC	1901800	biological_process	positive regulation of proteasomal protein catabolic process
Ad	0000502	cellular_component	proteasome complex
Ad	0005515	molecular_function	protein binding
Ad	0005634	cellular_component	nucleus
Ad	0005654	cellular_component	nucleoplasm
Ad	0005829	cellular_component	cytosol
Ad	0005838	cellular_component	proteasome regulatory particle
Ad	0006979	biological_process	response to oxidative stress
Ad	0008021	cellular_component	synaptic vesicle
Ad	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
Ad	0010498	biological_process	proteasomal protein catabolic process
Ad	0022624	cellular_component	proteasome accessory complex
Ad	0032991	cellular_component	protein-containing complex
Ad	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Ad	0061136	biological_process	regulation of proteasomal protein catabolic process
Ad	0071357	biological_process	cellular response to type I interferon
AD	0000502	cellular_component	proteasome complex
AD	0005515	molecular_function	protein binding
AD	0005634	cellular_component	nucleus
AD	0005654	cellular_component	nucleoplasm
AD	0005737	cellular_component	cytoplasm
AD	0005829	cellular_component	cytosol
AD	0006508	biological_process	proteolysis
AD	0006979	biological_process	response to oxidative stress
AD	0008021	cellular_component	synaptic vesicle
AD	0010498	biological_process	proteasomal protein catabolic process
AD	0016020	cellular_component	membrane
AD	0022624	cellular_component	proteasome accessory complex
AD	0036402	molecular_function	proteasome-activating activity
AD	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AD	0061136	biological_process	regulation of proteasomal protein catabolic process
AD	0071357	biological_process	cellular response to type I interferon
Ae	0000502	cellular_component	proteasome complex
Ae	0005515	molecular_function	protein binding
Ae	0005634	cellular_component	nucleus
Ae	0005654	cellular_component	nucleoplasm
Ae	0005829	cellular_component	cytosol
Ae	0006406	biological_process	mRNA export from nucleus
Ae	0006979	biological_process	response to oxidative stress
Ae	0008021	cellular_component	synaptic vesicle
Ae	0010498	biological_process	proteasomal protein catabolic process
Ae	0032039	cellular_component	integrator complex
Ae	0032991	cellular_component	protein-containing complex
Ae	0043130	molecular_function	ubiquitin binding
Ae	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Ae	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Ae	0061136	biological_process	regulation of proteasomal protein catabolic process
Ae	0070390	cellular_component	transcription export complex 2
Ae	0071357	biological_process	cellular response to type I interferon
AE	0005634	cellular_component	nucleus
AE	0005737	cellular_component	cytoplasm
Af	0000502	cellular_component	proteasome complex
Af	0005515	molecular_function	protein binding
Af	0005576	cellular_component	extracellular region
Af	0005654	cellular_component	nucleoplasm
Af	0005829	cellular_component	cytosol
Af	0005838	cellular_component	proteasome regulatory particle
Af	0006979	biological_process	response to oxidative stress
Af	0008021	cellular_component	synaptic vesicle
Af	0010498	biological_process	proteasomal protein catabolic process
Af	0016020	cellular_component	membrane
Af	0022624	cellular_component	proteasome accessory complex
Af	0034515	cellular_component	proteasome storage granule
Af	0034774	cellular_component	secretory granule lumen
Af	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Af	0061136	biological_process	regulation of proteasomal protein catabolic process
Af	0070062	cellular_component	extracellular exosome
Af	0071357	biological_process	cellular response to type I interferon
Af	1904813	cellular_component	ficolin-1-rich granule lumen
AF	0000502	cellular_component	proteasome complex
AF	0000932	cellular_component	P-body
AF	0005515	molecular_function	protein binding
AF	0005576	cellular_component	extracellular region
AF	0005634	cellular_component	nucleus
AF	0005654	cellular_component	nucleoplasm
AF	0005737	cellular_component	cytoplasm
AF	0005829	cellular_component	cytosol
AF	0006979	biological_process	response to oxidative stress
AF	0008021	cellular_component	synaptic vesicle
AF	0010498	biological_process	proteasomal protein catabolic process
AF	0016020	cellular_component	membrane
AF	0022624	cellular_component	proteasome accessory complex
AF	0034774	cellular_component	secretory granule lumen
AF	0036402	molecular_function	proteasome-activating activity
AF	0042802	molecular_function	identical protein binding
AF	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AF	0043921	biological_process	host-mediated perturbation of viral transcription
AF	0045944	biological_process	positive regulation of transcription by RNA polymerase II
AF	0061136	biological_process	regulation of proteasomal protein catabolic process
AF	0071357	biological_process	cellular response to type I interferon
AF	1901800	biological_process	positive regulation of proteasomal protein catabolic process
AF	1904813	cellular_component	ficolin-1-rich granule lumen
AG	0000502	cellular_component	proteasome complex
AG	0000932	cellular_component	P-body
AG	0002376	biological_process	immune system process
AG	0003723	molecular_function	RNA binding
AG	0004175	molecular_function	endopeptidase activity
AG	0005515	molecular_function	protein binding
AG	0005634	cellular_component	nucleus
AG	0005654	cellular_component	nucleoplasm
AG	0005737	cellular_component	cytoplasm
AG	0005829	cellular_component	cytosol
AG	0005839	cellular_component	proteasome core complex
AG	0005840	cellular_component	ribosome
AG	0006281	biological_process	DNA repair
AG	0006915	biological_process	apoptotic process
AG	0006974	biological_process	DNA damage response
AG	0006979	biological_process	response to oxidative stress
AG	0007283	biological_process	spermatogenesis
AG	0008021	cellular_component	synaptic vesicle
AG	0010498	biological_process	proteasomal protein catabolic process
AG	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AG	0016363	cellular_component	nuclear matrix
AG	0019773	cellular_component	proteasome core complex, alpha-subunit complex
AG	0030016	cellular_component	myofibril
AG	0030017	cellular_component	sarcomere
AG	0030163	biological_process	protein catabolic process
AG	0030317	biological_process	flagellated sperm motility
AG	0032729	biological_process	positive regulation of type II interferon production
AG	0032743	biological_process	positive regulation of interleukin-2 production
AG	0032760	biological_process	positive regulation of tumor necrosis factor production
AG	0034341	biological_process	response to type II interferon
AG	0034515	cellular_component	proteasome storage granule
AG	0035639	molecular_function	purine ribonucleoside triphosphate binding
AG	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
AG	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AG	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AG	0045061	biological_process	thymic T cell selection
AG	0045063	biological_process	T-helper 1 cell differentiation
AG	0045590	biological_process	negative regulation of regulatory T cell differentiation
AG	0050727	biological_process	regulation of inflammatory response
AG	0051059	molecular_function	NF-kappaB binding
AG	0051321	biological_process	meiotic cell cycle
AG	0061136	biological_process	regulation of proteasomal protein catabolic process
AG	0070062	cellular_component	extracellular exosome
AG	0071357	biological_process	cellular response to type I interferon
AG	0072539	biological_process	T-helper 17 cell differentiation
AG	0097229	cellular_component	sperm end piece
AG	0097542	cellular_component	ciliary tip
AG	0140756	molecular_function	structural constituent of proteasome
AG	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AG	1990111	cellular_component	spermatoproteasome complex
AG	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AH	0000502	cellular_component	proteasome complex
AH	0000932	cellular_component	P-body
AH	0002376	biological_process	immune system process
AH	0005515	molecular_function	protein binding
AH	0005576	cellular_component	extracellular region
AH	0005634	cellular_component	nucleus
AH	0005654	cellular_component	nucleoplasm
AH	0005737	cellular_component	cytoplasm
AH	0005829	cellular_component	cytosol
AH	0005839	cellular_component	proteasome core complex
AH	0006281	biological_process	DNA repair
AH	0006915	biological_process	apoptotic process
AH	0006974	biological_process	DNA damage response
AH	0006979	biological_process	response to oxidative stress
AH	0007283	biological_process	spermatogenesis
AH	0008021	cellular_component	synaptic vesicle
AH	0009615	biological_process	response to virus
AH	0010498	biological_process	proteasomal protein catabolic process
AH	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AH	0019773	cellular_component	proteasome core complex, alpha-subunit complex
AH	0030317	biological_process	flagellated sperm motility
AH	0032729	biological_process	positive regulation of type II interferon production
AH	0032743	biological_process	positive regulation of interleukin-2 production
AH	0032760	biological_process	positive regulation of tumor necrosis factor production
AH	0034341	biological_process	response to type II interferon
AH	0034515	cellular_component	proteasome storage granule
AH	0034774	cellular_component	secretory granule lumen
AH	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AH	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AH	0045061	biological_process	thymic T cell selection
AH	0045063	biological_process	T-helper 1 cell differentiation
AH	0045590	biological_process	negative regulation of regulatory T cell differentiation
AH	0051321	biological_process	meiotic cell cycle
AH	0061136	biological_process	regulation of proteasomal protein catabolic process
AH	0070062	cellular_component	extracellular exosome
AH	0071357	biological_process	cellular response to type I interferon
AH	0072539	biological_process	T-helper 17 cell differentiation
AH	0140756	molecular_function	structural constituent of proteasome
AH	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AH	1904813	cellular_component	ficolin-1-rich granule lumen
AH	1990111	cellular_component	spermatoproteasome complex
AH	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AI	0000502	cellular_component	proteasome complex
AI	0000932	cellular_component	P-body
AI	0002376	biological_process	immune system process
AI	0005515	molecular_function	protein binding
AI	0005634	cellular_component	nucleus
AI	0005654	cellular_component	nucleoplasm
AI	0005737	cellular_component	cytoplasm
AI	0005829	cellular_component	cytosol
AI	0005839	cellular_component	proteasome core complex
AI	0006281	biological_process	DNA repair
AI	0006915	biological_process	apoptotic process
AI	0006974	biological_process	DNA damage response
AI	0006979	biological_process	response to oxidative stress
AI	0007283	biological_process	spermatogenesis
AI	0008021	cellular_component	synaptic vesicle
AI	0010498	biological_process	proteasomal protein catabolic process
AI	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AI	0019773	cellular_component	proteasome core complex, alpha-subunit complex
AI	0030317	biological_process	flagellated sperm motility
AI	0032729	biological_process	positive regulation of type II interferon production
AI	0032743	biological_process	positive regulation of interleukin-2 production
AI	0032760	biological_process	positive regulation of tumor necrosis factor production
AI	0034341	biological_process	response to type II interferon
AI	0034515	cellular_component	proteasome storage granule
AI	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AI	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AI	0045061	biological_process	thymic T cell selection
AI	0045063	biological_process	T-helper 1 cell differentiation
AI	0045590	biological_process	negative regulation of regulatory T cell differentiation
AI	0051321	biological_process	meiotic cell cycle
AI	0061136	biological_process	regulation of proteasomal protein catabolic process
AI	0070062	cellular_component	extracellular exosome
AI	0071357	biological_process	cellular response to type I interferon
AI	0072539	biological_process	T-helper 17 cell differentiation
AI	0140756	molecular_function	structural constituent of proteasome
AI	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AI	1990111	cellular_component	spermatoproteasome complex
AI	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AJ	0000502	cellular_component	proteasome complex
AJ	0002376	biological_process	immune system process
AJ	0005515	molecular_function	protein binding
AJ	0005634	cellular_component	nucleus
AJ	0005654	cellular_component	nucleoplasm
AJ	0005737	cellular_component	cytoplasm
AJ	0005829	cellular_component	cytosol
AJ	0005839	cellular_component	proteasome core complex
AJ	0006281	biological_process	DNA repair
AJ	0006915	biological_process	apoptotic process
AJ	0006974	biological_process	DNA damage response
AJ	0006979	biological_process	response to oxidative stress
AJ	0008021	cellular_component	synaptic vesicle
AJ	0010498	biological_process	proteasomal protein catabolic process
AJ	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AJ	0019773	cellular_component	proteasome core complex, alpha-subunit complex
AJ	0030317	biological_process	flagellated sperm motility
AJ	0032729	biological_process	positive regulation of type II interferon production
AJ	0032743	biological_process	positive regulation of interleukin-2 production
AJ	0032760	biological_process	positive regulation of tumor necrosis factor production
AJ	0034341	biological_process	response to type II interferon
AJ	0034515	cellular_component	proteasome storage granule
AJ	0042802	molecular_function	identical protein binding
AJ	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AJ	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AJ	0045061	biological_process	thymic T cell selection
AJ	0045063	biological_process	T-helper 1 cell differentiation
AJ	0045590	biological_process	negative regulation of regulatory T cell differentiation
AJ	0061136	biological_process	regulation of proteasomal protein catabolic process
AJ	0070062	cellular_component	extracellular exosome
AJ	0071357	biological_process	cellular response to type I interferon
AJ	0072539	biological_process	T-helper 17 cell differentiation
AJ	0140756	molecular_function	structural constituent of proteasome
AJ	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AJ	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AK	0000502	cellular_component	proteasome complex
AK	0002376	biological_process	immune system process
AK	0005515	molecular_function	protein binding
AK	0005576	cellular_component	extracellular region
AK	0005634	cellular_component	nucleus
AK	0005654	cellular_component	nucleoplasm
AK	0005737	cellular_component	cytoplasm
AK	0005829	cellular_component	cytosol
AK	0005839	cellular_component	proteasome core complex
AK	0006281	biological_process	DNA repair
AK	0006915	biological_process	apoptotic process
AK	0006974	biological_process	DNA damage response
AK	0006979	biological_process	response to oxidative stress
AK	0007283	biological_process	spermatogenesis
AK	0008021	cellular_component	synaptic vesicle
AK	0010498	biological_process	proteasomal protein catabolic process
AK	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AK	0019773	cellular_component	proteasome core complex, alpha-subunit complex
AK	0030317	biological_process	flagellated sperm motility
AK	0032729	biological_process	positive regulation of type II interferon production
AK	0032743	biological_process	positive regulation of interleukin-2 production
AK	0032760	biological_process	positive regulation of tumor necrosis factor production
AK	0034341	biological_process	response to type II interferon
AK	0034515	cellular_component	proteasome storage granule
AK	0034774	cellular_component	secretory granule lumen
AK	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AK	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AK	0045061	biological_process	thymic T cell selection
AK	0045063	biological_process	T-helper 1 cell differentiation
AK	0045590	biological_process	negative regulation of regulatory T cell differentiation
AK	0051321	biological_process	meiotic cell cycle
AK	0061136	biological_process	regulation of proteasomal protein catabolic process
AK	0070062	cellular_component	extracellular exosome
AK	0071357	biological_process	cellular response to type I interferon
AK	0072539	biological_process	T-helper 17 cell differentiation
AK	0140756	molecular_function	structural constituent of proteasome
AK	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AK	1904813	cellular_component	ficolin-1-rich granule lumen
AK	1990111	cellular_component	spermatoproteasome complex
AK	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AL	0000502	cellular_component	proteasome complex
AL	0001530	molecular_function	lipopolysaccharide binding
AL	0002376	biological_process	immune system process
AL	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
AL	0005515	molecular_function	protein binding
AL	0005634	cellular_component	nucleus
AL	0005654	cellular_component	nucleoplasm
AL	0005737	cellular_component	cytoplasm
AL	0005829	cellular_component	cytosol
AL	0005839	cellular_component	proteasome core complex
AL	0006281	biological_process	DNA repair
AL	0006915	biological_process	apoptotic process
AL	0006974	biological_process	DNA damage response
AL	0006979	biological_process	response to oxidative stress
AL	0007283	biological_process	spermatogenesis
AL	0008021	cellular_component	synaptic vesicle
AL	0010498	biological_process	proteasomal protein catabolic process
AL	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AL	0016604	cellular_component	nuclear body
AL	0019773	cellular_component	proteasome core complex, alpha-subunit complex
AL	0030317	biological_process	flagellated sperm motility
AL	0032729	biological_process	positive regulation of type II interferon production
AL	0032743	biological_process	positive regulation of interleukin-2 production
AL	0032760	biological_process	positive regulation of tumor necrosis factor production
AL	0034341	biological_process	response to type II interferon
AL	0034515	cellular_component	proteasome storage granule
AL	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AL	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AL	0045061	biological_process	thymic T cell selection
AL	0045063	biological_process	T-helper 1 cell differentiation
AL	0045590	biological_process	negative regulation of regulatory T cell differentiation
AL	0051321	biological_process	meiotic cell cycle
AL	0061136	biological_process	regulation of proteasomal protein catabolic process
AL	0070062	cellular_component	extracellular exosome
AL	0071357	biological_process	cellular response to type I interferon
AL	0072539	biological_process	T-helper 17 cell differentiation
AL	0140756	molecular_function	structural constituent of proteasome
AL	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AL	1990111	cellular_component	spermatoproteasome complex
AL	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AM	0000502	cellular_component	proteasome complex
AM	0002376	biological_process	immune system process
AM	0005515	molecular_function	protein binding
AM	0005634	cellular_component	nucleus
AM	0005654	cellular_component	nucleoplasm
AM	0005737	cellular_component	cytoplasm
AM	0005829	cellular_component	cytosol
AM	0005839	cellular_component	proteasome core complex
AM	0006281	biological_process	DNA repair
AM	0006915	biological_process	apoptotic process
AM	0006974	biological_process	DNA damage response
AM	0006979	biological_process	response to oxidative stress
AM	0007283	biological_process	spermatogenesis
AM	0008021	cellular_component	synaptic vesicle
AM	0010498	biological_process	proteasomal protein catabolic process
AM	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AM	0019773	cellular_component	proteasome core complex, alpha-subunit complex
AM	0030317	biological_process	flagellated sperm motility
AM	0031625	molecular_function	ubiquitin protein ligase binding
AM	0032729	biological_process	positive regulation of type II interferon production
AM	0032743	biological_process	positive regulation of interleukin-2 production
AM	0032760	biological_process	positive regulation of tumor necrosis factor production
AM	0034341	biological_process	response to type II interferon
AM	0034515	cellular_component	proteasome storage granule
AM	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AM	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AM	0045061	biological_process	thymic T cell selection
AM	0045063	biological_process	T-helper 1 cell differentiation
AM	0045590	biological_process	negative regulation of regulatory T cell differentiation
AM	0051321	biological_process	meiotic cell cycle
AM	0061136	biological_process	regulation of proteasomal protein catabolic process
AM	0070062	cellular_component	extracellular exosome
AM	0071357	biological_process	cellular response to type I interferon
AM	0072539	biological_process	T-helper 17 cell differentiation
AM	0140756	molecular_function	structural constituent of proteasome
AM	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AM	1990111	cellular_component	spermatoproteasome complex
AM	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AN	0000502	cellular_component	proteasome complex
AN	0004175	molecular_function	endopeptidase activity
AN	0004298	molecular_function	threonine-type endopeptidase activity
AN	0005515	molecular_function	protein binding
AN	0005634	cellular_component	nucleus
AN	0005654	cellular_component	nucleoplasm
AN	0005737	cellular_component	cytoplasm
AN	0005829	cellular_component	cytosol
AN	0005839	cellular_component	proteasome core complex
AN	0006281	biological_process	DNA repair
AN	0006915	biological_process	apoptotic process
AN	0006974	biological_process	DNA damage response
AN	0006979	biological_process	response to oxidative stress
AN	0007283	biological_process	spermatogenesis
AN	0008021	cellular_component	synaptic vesicle
AN	0010498	biological_process	proteasomal protein catabolic process
AN	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AN	0019774	cellular_component	proteasome core complex, beta-subunit complex
AN	0030317	biological_process	flagellated sperm motility
AN	0034515	cellular_component	proteasome storage granule
AN	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AN	0045296	molecular_function	cadherin binding
AN	0051321	biological_process	meiotic cell cycle
AN	0061136	biological_process	regulation of proteasomal protein catabolic process
AN	0070062	cellular_component	extracellular exosome
AN	0071357	biological_process	cellular response to type I interferon
AN	1990111	cellular_component	spermatoproteasome complex
AN	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AO	0000502	cellular_component	proteasome complex
AO	0004175	molecular_function	endopeptidase activity
AO	0004298	molecular_function	threonine-type endopeptidase activity
AO	0005515	molecular_function	protein binding
AO	0005576	cellular_component	extracellular region
AO	0005634	cellular_component	nucleus
AO	0005654	cellular_component	nucleoplasm
AO	0005737	cellular_component	cytoplasm
AO	0005829	cellular_component	cytosol
AO	0005839	cellular_component	proteasome core complex
AO	0006281	biological_process	DNA repair
AO	0006915	biological_process	apoptotic process
AO	0006974	biological_process	DNA damage response
AO	0006979	biological_process	response to oxidative stress
AO	0007283	biological_process	spermatogenesis
AO	0008021	cellular_component	synaptic vesicle
AO	0010498	biological_process	proteasomal protein catabolic process
AO	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AO	0016604	cellular_component	nuclear body
AO	0019774	cellular_component	proteasome core complex, beta-subunit complex
AO	0030317	biological_process	flagellated sperm motility
AO	0034515	cellular_component	proteasome storage granule
AO	0034774	cellular_component	secretory granule lumen
AO	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AO	0051321	biological_process	meiotic cell cycle
AO	0061136	biological_process	regulation of proteasomal protein catabolic process
AO	0071357	biological_process	cellular response to type I interferon
AO	1904813	cellular_component	ficolin-1-rich granule lumen
AO	1990111	cellular_component	spermatoproteasome complex
AO	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AP	0000502	cellular_component	proteasome complex
AP	0002376	biological_process	immune system process
AP	0005515	molecular_function	protein binding
AP	0005634	cellular_component	nucleus
AP	0005654	cellular_component	nucleoplasm
AP	0005737	cellular_component	cytoplasm
AP	0005829	cellular_component	cytosol
AP	0005839	cellular_component	proteasome core complex
AP	0006281	biological_process	DNA repair
AP	0006915	biological_process	apoptotic process
AP	0006974	biological_process	DNA damage response
AP	0006979	biological_process	response to oxidative stress
AP	0007283	biological_process	spermatogenesis
AP	0008021	cellular_component	synaptic vesicle
AP	0010498	biological_process	proteasomal protein catabolic process
AP	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AP	0019774	cellular_component	proteasome core complex, beta-subunit complex
AP	0030317	biological_process	flagellated sperm motility
AP	0032729	biological_process	positive regulation of type II interferon production
AP	0032743	biological_process	positive regulation of interleukin-2 production
AP	0032760	biological_process	positive regulation of tumor necrosis factor production
AP	0034341	biological_process	response to type II interferon
AP	0034515	cellular_component	proteasome storage granule
AP	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AP	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AP	0045061	biological_process	thymic T cell selection
AP	0045063	biological_process	T-helper 1 cell differentiation
AP	0045590	biological_process	negative regulation of regulatory T cell differentiation
AP	0051321	biological_process	meiotic cell cycle
AP	0061136	biological_process	regulation of proteasomal protein catabolic process
AP	0070062	cellular_component	extracellular exosome
AP	0071357	biological_process	cellular response to type I interferon
AP	0072539	biological_process	T-helper 17 cell differentiation
AP	0140756	molecular_function	structural constituent of proteasome
AP	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AP	1990111	cellular_component	spermatoproteasome complex
AP	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AQ	0000502	cellular_component	proteasome complex
AQ	0002376	biological_process	immune system process
AQ	0005515	molecular_function	protein binding
AQ	0005634	cellular_component	nucleus
AQ	0005654	cellular_component	nucleoplasm
AQ	0005737	cellular_component	cytoplasm
AQ	0005829	cellular_component	cytosol
AQ	0005839	cellular_component	proteasome core complex
AQ	0006281	biological_process	DNA repair
AQ	0006915	biological_process	apoptotic process
AQ	0006974	biological_process	DNA damage response
AQ	0006979	biological_process	response to oxidative stress
AQ	0007283	biological_process	spermatogenesis
AQ	0008021	cellular_component	synaptic vesicle
AQ	0010498	biological_process	proteasomal protein catabolic process
AQ	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AQ	0016020	cellular_component	membrane
AQ	0019774	cellular_component	proteasome core complex, beta-subunit complex
AQ	0030317	biological_process	flagellated sperm motility
AQ	0032729	biological_process	positive regulation of type II interferon production
AQ	0032743	biological_process	positive regulation of interleukin-2 production
AQ	0032760	biological_process	positive regulation of tumor necrosis factor production
AQ	0034341	biological_process	response to type II interferon
AQ	0034515	cellular_component	proteasome storage granule
AQ	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AQ	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AQ	0045061	biological_process	thymic T cell selection
AQ	0045063	biological_process	T-helper 1 cell differentiation
AQ	0045590	biological_process	negative regulation of regulatory T cell differentiation
AQ	0051321	biological_process	meiotic cell cycle
AQ	0061136	biological_process	regulation of proteasomal protein catabolic process
AQ	0070062	cellular_component	extracellular exosome
AQ	0071357	biological_process	cellular response to type I interferon
AQ	0072539	biological_process	T-helper 17 cell differentiation
AQ	0140756	molecular_function	structural constituent of proteasome
AQ	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AQ	1990111	cellular_component	spermatoproteasome complex
AQ	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AR	0000502	cellular_component	proteasome complex
AR	0004175	molecular_function	endopeptidase activity
AR	0004298	molecular_function	threonine-type endopeptidase activity
AR	0005515	molecular_function	protein binding
AR	0005634	cellular_component	nucleus
AR	0005654	cellular_component	nucleoplasm
AR	0005737	cellular_component	cytoplasm
AR	0005829	cellular_component	cytosol
AR	0005839	cellular_component	proteasome core complex
AR	0006281	biological_process	DNA repair
AR	0006508	biological_process	proteolysis
AR	0006915	biological_process	apoptotic process
AR	0006974	biological_process	DNA damage response
AR	0006979	biological_process	response to oxidative stress
AR	0007283	biological_process	spermatogenesis
AR	0008021	cellular_component	synaptic vesicle
AR	0008233	molecular_function	peptidase activity
AR	0010498	biological_process	proteasomal protein catabolic process
AR	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AR	0019774	cellular_component	proteasome core complex, beta-subunit complex
AR	0030317	biological_process	flagellated sperm motility
AR	0034515	cellular_component	proteasome storage granule
AR	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AR	0043248	biological_process	proteasome assembly
AR	0051321	biological_process	meiotic cell cycle
AR	0061136	biological_process	regulation of proteasomal protein catabolic process
AR	0070062	cellular_component	extracellular exosome
AR	0071357	biological_process	cellular response to type I interferon
AR	1990111	cellular_component	spermatoproteasome complex
AR	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AS	0000502	cellular_component	proteasome complex
AS	0002376	biological_process	immune system process
AS	0005515	molecular_function	protein binding
AS	0005576	cellular_component	extracellular region
AS	0005634	cellular_component	nucleus
AS	0005654	cellular_component	nucleoplasm
AS	0005737	cellular_component	cytoplasm
AS	0005829	cellular_component	cytosol
AS	0005839	cellular_component	proteasome core complex
AS	0006281	biological_process	DNA repair
AS	0006915	biological_process	apoptotic process
AS	0006974	biological_process	DNA damage response
AS	0006979	biological_process	response to oxidative stress
AS	0007283	biological_process	spermatogenesis
AS	0008021	cellular_component	synaptic vesicle
AS	0010498	biological_process	proteasomal protein catabolic process
AS	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AS	0019774	cellular_component	proteasome core complex, beta-subunit complex
AS	0030317	biological_process	flagellated sperm motility
AS	0032729	biological_process	positive regulation of type II interferon production
AS	0032743	biological_process	positive regulation of interleukin-2 production
AS	0032760	biological_process	positive regulation of tumor necrosis factor production
AS	0034341	biological_process	response to type II interferon
AS	0034515	cellular_component	proteasome storage granule
AS	0034774	cellular_component	secretory granule lumen
AS	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AS	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AS	0045061	biological_process	thymic T cell selection
AS	0045063	biological_process	T-helper 1 cell differentiation
AS	0045590	biological_process	negative regulation of regulatory T cell differentiation
AS	0051321	biological_process	meiotic cell cycle
AS	0061136	biological_process	regulation of proteasomal protein catabolic process
AS	0070062	cellular_component	extracellular exosome
AS	0071357	biological_process	cellular response to type I interferon
AS	0072539	biological_process	T-helper 17 cell differentiation
AS	0140756	molecular_function	structural constituent of proteasome
AS	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AS	1904813	cellular_component	ficolin-1-rich granule lumen
AS	1990111	cellular_component	spermatoproteasome complex
AS	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AT	0000502	cellular_component	proteasome complex
AT	0001530	molecular_function	lipopolysaccharide binding
AT	0002376	biological_process	immune system process
AT	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
AT	0005515	molecular_function	protein binding
AT	0005634	cellular_component	nucleus
AT	0005654	cellular_component	nucleoplasm
AT	0005737	cellular_component	cytoplasm
AT	0005829	cellular_component	cytosol
AT	0005839	cellular_component	proteasome core complex
AT	0006281	biological_process	DNA repair
AT	0006915	biological_process	apoptotic process
AT	0006974	biological_process	DNA damage response
AT	0006979	biological_process	response to oxidative stress
AT	0007283	biological_process	spermatogenesis
AT	0008021	cellular_component	synaptic vesicle
AT	0010498	biological_process	proteasomal protein catabolic process
AT	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
AT	0019774	cellular_component	proteasome core complex, beta-subunit complex
AT	0030317	biological_process	flagellated sperm motility
AT	0032729	biological_process	positive regulation of type II interferon production
AT	0032743	biological_process	positive regulation of interleukin-2 production
AT	0032760	biological_process	positive regulation of tumor necrosis factor production
AT	0034341	biological_process	response to type II interferon
AT	0034515	cellular_component	proteasome storage granule
AT	0036064	cellular_component	ciliary basal body
AT	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AT	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
AT	0045061	biological_process	thymic T cell selection
AT	0045063	biological_process	T-helper 1 cell differentiation
AT	0045590	biological_process	negative regulation of regulatory T cell differentiation
AT	0051321	biological_process	meiotic cell cycle
AT	0061136	biological_process	regulation of proteasomal protein catabolic process
AT	0070062	cellular_component	extracellular exosome
AT	0071357	biological_process	cellular response to type I interferon
AT	0072539	biological_process	T-helper 17 cell differentiation
AT	0140756	molecular_function	structural constituent of proteasome
AT	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
AT	1990111	cellular_component	spermatoproteasome complex
AT	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
AU	0000502	cellular_component	proteasome complex
AU	0005515	molecular_function	protein binding
AU	0005576	cellular_component	extracellular region
AU	0005654	cellular_component	nucleoplasm
AU	0005829	cellular_component	cytosol
AU	0005838	cellular_component	proteasome regulatory particle
AU	0006979	biological_process	response to oxidative stress
AU	0008021	cellular_component	synaptic vesicle
AU	0010498	biological_process	proteasomal protein catabolic process
AU	0016020	cellular_component	membrane
AU	0022624	cellular_component	proteasome accessory complex
AU	0031625	molecular_function	ubiquitin protein ligase binding
AU	0034515	cellular_component	proteasome storage granule
AU	0035578	cellular_component	azurophil granule lumen
AU	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AU	0061136	biological_process	regulation of proteasomal protein catabolic process
AU	0071357	biological_process	cellular response to type I interferon
AV	0000502	cellular_component	proteasome complex
AV	0005515	molecular_function	protein binding
AV	0005576	cellular_component	extracellular region
AV	0005634	cellular_component	nucleus
AV	0005654	cellular_component	nucleoplasm
AV	0005829	cellular_component	cytosol
AV	0005838	cellular_component	proteasome regulatory particle
AV	0006511	biological_process	ubiquitin-dependent protein catabolic process
AV	0006979	biological_process	response to oxidative stress
AV	0008021	cellular_component	synaptic vesicle
AV	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
AV	0010498	biological_process	proteasomal protein catabolic process
AV	0016020	cellular_component	membrane
AV	0022624	cellular_component	proteasome accessory complex
AV	0034774	cellular_component	secretory granule lumen
AV	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AV	0061136	biological_process	regulation of proteasomal protein catabolic process
AV	0070062	cellular_component	extracellular exosome
AV	0071357	biological_process	cellular response to type I interferon
AV	1904813	cellular_component	ficolin-1-rich granule lumen
AW	0000502	cellular_component	proteasome complex
AW	0005515	molecular_function	protein binding
AW	0005576	cellular_component	extracellular region
AW	0005654	cellular_component	nucleoplasm
AW	0005829	cellular_component	cytosol
AW	0005838	cellular_component	proteasome regulatory particle
AW	0006979	biological_process	response to oxidative stress
AW	0008021	cellular_component	synaptic vesicle
AW	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
AW	0010498	biological_process	proteasomal protein catabolic process
AW	0016020	cellular_component	membrane
AW	0022624	cellular_component	proteasome accessory complex
AW	0034774	cellular_component	secretory granule lumen
AW	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AW	0061136	biological_process	regulation of proteasomal protein catabolic process
AW	0070062	cellular_component	extracellular exosome
AW	0071357	biological_process	cellular response to type I interferon
AW	1904813	cellular_component	ficolin-1-rich granule lumen
AX	0000502	cellular_component	proteasome complex
AX	0005198	molecular_function	structural molecule activity
AX	0005515	molecular_function	protein binding
AX	0005576	cellular_component	extracellular region
AX	0005634	cellular_component	nucleus
AX	0005654	cellular_component	nucleoplasm
AX	0005829	cellular_component	cytosol
AX	0005838	cellular_component	proteasome regulatory particle
AX	0006511	biological_process	ubiquitin-dependent protein catabolic process
AX	0006979	biological_process	response to oxidative stress
AX	0008021	cellular_component	synaptic vesicle
AX	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
AX	0010498	biological_process	proteasomal protein catabolic process
AX	0016020	cellular_component	membrane
AX	0022624	cellular_component	proteasome accessory complex
AX	0032991	cellular_component	protein-containing complex
AX	0034774	cellular_component	secretory granule lumen
AX	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AX	0043248	biological_process	proteasome assembly
AX	0048863	biological_process	stem cell differentiation
AX	0061136	biological_process	regulation of proteasomal protein catabolic process
AX	0071357	biological_process	cellular response to type I interferon
AX	1904813	cellular_component	ficolin-1-rich granule lumen
AY	0000502	cellular_component	proteasome complex
AY	0005515	molecular_function	protein binding
AY	0005576	cellular_component	extracellular region
AY	0005654	cellular_component	nucleoplasm
AY	0005829	cellular_component	cytosol
AY	0005838	cellular_component	proteasome regulatory particle
AY	0006979	biological_process	response to oxidative stress
AY	0008021	cellular_component	synaptic vesicle
AY	0010498	biological_process	proteasomal protein catabolic process
AY	0022624	cellular_component	proteasome accessory complex
AY	0032991	cellular_component	protein-containing complex
AY	0034774	cellular_component	secretory granule lumen
AY	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AY	0061136	biological_process	regulation of proteasomal protein catabolic process
AY	0071357	biological_process	cellular response to type I interferon
AY	1904813	cellular_component	ficolin-1-rich granule lumen
AZ	0000502	cellular_component	proteasome complex
AZ	0005515	molecular_function	protein binding
AZ	0005576	cellular_component	extracellular region
AZ	0005634	cellular_component	nucleus
AZ	0005654	cellular_component	nucleoplasm
AZ	0005829	cellular_component	cytosol
AZ	0005838	cellular_component	proteasome regulatory particle
AZ	0006979	biological_process	response to oxidative stress
AZ	0008021	cellular_component	synaptic vesicle
AZ	0008233	molecular_function	peptidase activity
AZ	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
AZ	0010498	biological_process	proteasomal protein catabolic process
AZ	0016020	cellular_component	membrane
AZ	0034774	cellular_component	secretory granule lumen
AZ	0042803	molecular_function	protein homodimerization activity
AZ	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
AZ	0061136	biological_process	regulation of proteasomal protein catabolic process
AZ	0070062	cellular_component	extracellular exosome
AZ	0071357	biological_process	cellular response to type I interferon
AZ	0140492	molecular_function	metal-dependent deubiquitinase activity
AZ	1904813	cellular_component	ficolin-1-rich granule lumen
Ba	0000502	cellular_component	proteasome complex
Ba	0005198	molecular_function	structural molecule activity
Ba	0005515	molecular_function	protein binding
Ba	0005576	cellular_component	extracellular region
Ba	0005634	cellular_component	nucleus
Ba	0005654	cellular_component	nucleoplasm
Ba	0005829	cellular_component	cytosol
Ba	0005838	cellular_component	proteasome regulatory particle
Ba	0006511	biological_process	ubiquitin-dependent protein catabolic process
Ba	0006979	biological_process	response to oxidative stress
Ba	0008021	cellular_component	synaptic vesicle
Ba	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
Ba	0010498	biological_process	proteasomal protein catabolic process
Ba	0016020	cellular_component	membrane
Ba	0022624	cellular_component	proteasome accessory complex
Ba	0034774	cellular_component	secretory granule lumen
Ba	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Ba	0061136	biological_process	regulation of proteasomal protein catabolic process
Ba	0071357	biological_process	cellular response to type I interferon
Ba	1904813	cellular_component	ficolin-1-rich granule lumen
BA	0000502	cellular_component	proteasome complex
BA	0000932	cellular_component	P-body
BA	0001649	biological_process	osteoblast differentiation
BA	0005515	molecular_function	protein binding
BA	0005576	cellular_component	extracellular region
BA	0005634	cellular_component	nucleus
BA	0005654	cellular_component	nucleoplasm
BA	0005737	cellular_component	cytoplasm
BA	0005829	cellular_component	cytosol
BA	0006511	biological_process	ubiquitin-dependent protein catabolic process
BA	0006979	biological_process	response to oxidative stress
BA	0008021	cellular_component	synaptic vesicle
BA	0010498	biological_process	proteasomal protein catabolic process
BA	0016020	cellular_component	membrane
BA	0022624	cellular_component	proteasome accessory complex
BA	0034774	cellular_component	secretory granule lumen
BA	0036402	molecular_function	proteasome-activating activity
BA	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
BA	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BA	0061136	biological_process	regulation of proteasomal protein catabolic process
BA	0071357	biological_process	cellular response to type I interferon
BA	1901800	biological_process	positive regulation of proteasomal protein catabolic process
BA	1904813	cellular_component	ficolin-1-rich granule lumen
Bb	0000502	cellular_component	proteasome complex
Bb	0003723	molecular_function	RNA binding
Bb	0005515	molecular_function	protein binding
Bb	0005634	cellular_component	nucleus
Bb	0005829	cellular_component	cytosol
Bb	0006979	biological_process	response to oxidative stress
Bb	0008021	cellular_component	synaptic vesicle
Bb	0010498	biological_process	proteasomal protein catabolic process
Bb	0022624	cellular_component	proteasome accessory complex
Bb	0042802	molecular_function	identical protein binding
Bb	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Bb	0060090	molecular_function	molecular adaptor activity
Bb	0061136	biological_process	regulation of proteasomal protein catabolic process
Bb	0071357	biological_process	cellular response to type I interferon
BB	0000502	cellular_component	proteasome complex
BB	0003723	molecular_function	RNA binding
BB	0005515	molecular_function	protein binding
BB	0005634	cellular_component	nucleus
BB	0005654	cellular_component	nucleoplasm
BB	0005737	cellular_component	cytoplasm
BB	0005829	cellular_component	cytosol
BB	0005838	cellular_component	proteasome regulatory particle
BB	0006979	biological_process	response to oxidative stress
BB	0008021	cellular_component	synaptic vesicle
BB	0010498	biological_process	proteasomal protein catabolic process
BB	0016020	cellular_component	membrane
BB	0022624	cellular_component	proteasome accessory complex
BB	0036402	molecular_function	proteasome-activating activity
BB	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BB	0061136	biological_process	regulation of proteasomal protein catabolic process
BB	0071357	biological_process	cellular response to type I interferon
Bc	0000502	cellular_component	proteasome complex
Bc	0000724	biological_process	double-strand break repair via homologous recombination
Bc	0004843	molecular_function	cysteine-type deubiquitinase activity
Bc	0005515	molecular_function	protein binding
Bc	0005576	cellular_component	extracellular region
Bc	0005634	cellular_component	nucleus
Bc	0005654	cellular_component	nucleoplasm
Bc	0005829	cellular_component	cytosol
Bc	0006303	biological_process	double-strand break repair via nonhomologous end joining
Bc	0006511	biological_process	ubiquitin-dependent protein catabolic process
Bc	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Bc	0006979	biological_process	response to oxidative stress
Bc	0008021	cellular_component	synaptic vesicle
Bc	0008237	molecular_function	metallopeptidase activity
Bc	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
Bc	0010498	biological_process	proteasomal protein catabolic process
Bc	0016241	biological_process	regulation of macroautophagy
Bc	0016579	biological_process	protein deubiquitination
Bc	0022624	cellular_component	proteasome accessory complex
Bc	0031597	cellular_component	cytosolic proteasome complex
Bc	0034774	cellular_component	secretory granule lumen
Bc	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Bc	0045471	biological_process	response to ethanol
Bc	0061133	molecular_function	endopeptidase activator activity
Bc	0061136	biological_process	regulation of proteasomal protein catabolic process
Bc	0061578	molecular_function	K63-linked deubiquitinase activity
Bc	0070536	biological_process	protein K63-linked deubiquitination
Bc	0070628	molecular_function	proteasome binding
Bc	0071357	biological_process	cellular response to type I interferon
Bc	0140492	molecular_function	metal-dependent deubiquitinase activity
Bc	1904813	cellular_component	ficolin-1-rich granule lumen
BC	0000502	cellular_component	proteasome complex
BC	0005102	molecular_function	signaling receptor binding
BC	0005515	molecular_function	protein binding
BC	0005634	cellular_component	nucleus
BC	0005654	cellular_component	nucleoplasm
BC	0005737	cellular_component	cytoplasm
BC	0005829	cellular_component	cytosol
BC	0005838	cellular_component	proteasome regulatory particle
BC	0005886	cellular_component	plasma membrane
BC	0006357	biological_process	regulation of transcription by RNA polymerase II
BC	0006979	biological_process	response to oxidative stress
BC	0008021	cellular_component	synaptic vesicle
BC	0008134	molecular_function	transcription factor binding
BC	0010498	biological_process	proteasomal protein catabolic process
BC	0016020	cellular_component	membrane
BC	0016234	cellular_component	inclusion body
BC	0016887	molecular_function	ATP hydrolysis activity
BC	0017025	molecular_function	TBP-class protein binding
BC	0022624	cellular_component	proteasome accessory complex
BC	0031410	cellular_component	cytoplasmic vesicle
BC	0031531	molecular_function	thyrotropin-releasing hormone receptor binding
BC	0031595	cellular_component	nuclear proteasome complex
BC	0031597	cellular_component	cytosolic proteasome complex
BC	0036402	molecular_function	proteasome-activating activity
BC	0043069	biological_process	negative regulation of programmed cell death
BC	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BC	0045893	biological_process	positive regulation of DNA-templated transcription
BC	0061136	biological_process	regulation of proteasomal protein catabolic process
BC	0070062	cellular_component	extracellular exosome
BC	0071357	biological_process	cellular response to type I interferon
BC	0072562	cellular_component	blood microparticle
BC	0090261	biological_process	positive regulation of inclusion body assembly
BC	0140296	molecular_function	general transcription initiation factor binding
BC	0140297	molecular_function	DNA-binding transcription factor binding
BC	1901800	biological_process	positive regulation of proteasomal protein catabolic process
Bd	0000502	cellular_component	proteasome complex
Bd	0005515	molecular_function	protein binding
Bd	0005634	cellular_component	nucleus
Bd	0005654	cellular_component	nucleoplasm
Bd	0005829	cellular_component	cytosol
Bd	0005838	cellular_component	proteasome regulatory particle
Bd	0006979	biological_process	response to oxidative stress
Bd	0008021	cellular_component	synaptic vesicle
Bd	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
Bd	0010498	biological_process	proteasomal protein catabolic process
Bd	0022624	cellular_component	proteasome accessory complex
Bd	0032991	cellular_component	protein-containing complex
Bd	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Bd	0061136	biological_process	regulation of proteasomal protein catabolic process
Bd	0071357	biological_process	cellular response to type I interferon
BD	0000502	cellular_component	proteasome complex
BD	0005515	molecular_function	protein binding
BD	0005634	cellular_component	nucleus
BD	0005654	cellular_component	nucleoplasm
BD	0005737	cellular_component	cytoplasm
BD	0005829	cellular_component	cytosol
BD	0006508	biological_process	proteolysis
BD	0006979	biological_process	response to oxidative stress
BD	0008021	cellular_component	synaptic vesicle
BD	0010498	biological_process	proteasomal protein catabolic process
BD	0016020	cellular_component	membrane
BD	0022624	cellular_component	proteasome accessory complex
BD	0036402	molecular_function	proteasome-activating activity
BD	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BD	0061136	biological_process	regulation of proteasomal protein catabolic process
BD	0071357	biological_process	cellular response to type I interferon
Be	0000502	cellular_component	proteasome complex
Be	0005515	molecular_function	protein binding
Be	0005634	cellular_component	nucleus
Be	0005654	cellular_component	nucleoplasm
Be	0005829	cellular_component	cytosol
Be	0006406	biological_process	mRNA export from nucleus
Be	0006979	biological_process	response to oxidative stress
Be	0008021	cellular_component	synaptic vesicle
Be	0010498	biological_process	proteasomal protein catabolic process
Be	0032039	cellular_component	integrator complex
Be	0032991	cellular_component	protein-containing complex
Be	0043130	molecular_function	ubiquitin binding
Be	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Be	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Be	0061136	biological_process	regulation of proteasomal protein catabolic process
Be	0070390	cellular_component	transcription export complex 2
Be	0071357	biological_process	cellular response to type I interferon
BE	0005634	cellular_component	nucleus
BE	0005737	cellular_component	cytoplasm
Bf	0000502	cellular_component	proteasome complex
Bf	0005515	molecular_function	protein binding
Bf	0005576	cellular_component	extracellular region
Bf	0005654	cellular_component	nucleoplasm
Bf	0005829	cellular_component	cytosol
Bf	0005838	cellular_component	proteasome regulatory particle
Bf	0006979	biological_process	response to oxidative stress
Bf	0008021	cellular_component	synaptic vesicle
Bf	0010498	biological_process	proteasomal protein catabolic process
Bf	0016020	cellular_component	membrane
Bf	0022624	cellular_component	proteasome accessory complex
Bf	0034515	cellular_component	proteasome storage granule
Bf	0034774	cellular_component	secretory granule lumen
Bf	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Bf	0061136	biological_process	regulation of proteasomal protein catabolic process
Bf	0070062	cellular_component	extracellular exosome
Bf	0071357	biological_process	cellular response to type I interferon
Bf	1904813	cellular_component	ficolin-1-rich granule lumen
BF	0000502	cellular_component	proteasome complex
BF	0000932	cellular_component	P-body
BF	0005515	molecular_function	protein binding
BF	0005576	cellular_component	extracellular region
BF	0005634	cellular_component	nucleus
BF	0005654	cellular_component	nucleoplasm
BF	0005737	cellular_component	cytoplasm
BF	0005829	cellular_component	cytosol
BF	0006979	biological_process	response to oxidative stress
BF	0008021	cellular_component	synaptic vesicle
BF	0010498	biological_process	proteasomal protein catabolic process
BF	0016020	cellular_component	membrane
BF	0022624	cellular_component	proteasome accessory complex
BF	0034774	cellular_component	secretory granule lumen
BF	0036402	molecular_function	proteasome-activating activity
BF	0042802	molecular_function	identical protein binding
BF	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BF	0043921	biological_process	host-mediated perturbation of viral transcription
BF	0045944	biological_process	positive regulation of transcription by RNA polymerase II
BF	0061136	biological_process	regulation of proteasomal protein catabolic process
BF	0071357	biological_process	cellular response to type I interferon
BF	1901800	biological_process	positive regulation of proteasomal protein catabolic process
BF	1904813	cellular_component	ficolin-1-rich granule lumen
BG	0000502	cellular_component	proteasome complex
BG	0000932	cellular_component	P-body
BG	0002376	biological_process	immune system process
BG	0003723	molecular_function	RNA binding
BG	0004175	molecular_function	endopeptidase activity
BG	0005515	molecular_function	protein binding
BG	0005634	cellular_component	nucleus
BG	0005654	cellular_component	nucleoplasm
BG	0005737	cellular_component	cytoplasm
BG	0005829	cellular_component	cytosol
BG	0005839	cellular_component	proteasome core complex
BG	0005840	cellular_component	ribosome
BG	0006281	biological_process	DNA repair
BG	0006915	biological_process	apoptotic process
BG	0006974	biological_process	DNA damage response
BG	0006979	biological_process	response to oxidative stress
BG	0007283	biological_process	spermatogenesis
BG	0008021	cellular_component	synaptic vesicle
BG	0010498	biological_process	proteasomal protein catabolic process
BG	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BG	0016363	cellular_component	nuclear matrix
BG	0019773	cellular_component	proteasome core complex, alpha-subunit complex
BG	0030016	cellular_component	myofibril
BG	0030017	cellular_component	sarcomere
BG	0030163	biological_process	protein catabolic process
BG	0030317	biological_process	flagellated sperm motility
BG	0032729	biological_process	positive regulation of type II interferon production
BG	0032743	biological_process	positive regulation of interleukin-2 production
BG	0032760	biological_process	positive regulation of tumor necrosis factor production
BG	0034341	biological_process	response to type II interferon
BG	0034515	cellular_component	proteasome storage granule
BG	0035639	molecular_function	purine ribonucleoside triphosphate binding
BG	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
BG	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BG	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BG	0045061	biological_process	thymic T cell selection
BG	0045063	biological_process	T-helper 1 cell differentiation
BG	0045590	biological_process	negative regulation of regulatory T cell differentiation
BG	0050727	biological_process	regulation of inflammatory response
BG	0051059	molecular_function	NF-kappaB binding
BG	0051321	biological_process	meiotic cell cycle
BG	0061136	biological_process	regulation of proteasomal protein catabolic process
BG	0070062	cellular_component	extracellular exosome
BG	0071357	biological_process	cellular response to type I interferon
BG	0072539	biological_process	T-helper 17 cell differentiation
BG	0097229	cellular_component	sperm end piece
BG	0097542	cellular_component	ciliary tip
BG	0140756	molecular_function	structural constituent of proteasome
BG	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BG	1990111	cellular_component	spermatoproteasome complex
BG	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BH	0000502	cellular_component	proteasome complex
BH	0000932	cellular_component	P-body
BH	0002376	biological_process	immune system process
BH	0005515	molecular_function	protein binding
BH	0005576	cellular_component	extracellular region
BH	0005634	cellular_component	nucleus
BH	0005654	cellular_component	nucleoplasm
BH	0005737	cellular_component	cytoplasm
BH	0005829	cellular_component	cytosol
BH	0005839	cellular_component	proteasome core complex
BH	0006281	biological_process	DNA repair
BH	0006915	biological_process	apoptotic process
BH	0006974	biological_process	DNA damage response
BH	0006979	biological_process	response to oxidative stress
BH	0007283	biological_process	spermatogenesis
BH	0008021	cellular_component	synaptic vesicle
BH	0009615	biological_process	response to virus
BH	0010498	biological_process	proteasomal protein catabolic process
BH	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BH	0019773	cellular_component	proteasome core complex, alpha-subunit complex
BH	0030317	biological_process	flagellated sperm motility
BH	0032729	biological_process	positive regulation of type II interferon production
BH	0032743	biological_process	positive regulation of interleukin-2 production
BH	0032760	biological_process	positive regulation of tumor necrosis factor production
BH	0034341	biological_process	response to type II interferon
BH	0034515	cellular_component	proteasome storage granule
BH	0034774	cellular_component	secretory granule lumen
BH	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BH	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BH	0045061	biological_process	thymic T cell selection
BH	0045063	biological_process	T-helper 1 cell differentiation
BH	0045590	biological_process	negative regulation of regulatory T cell differentiation
BH	0051321	biological_process	meiotic cell cycle
BH	0061136	biological_process	regulation of proteasomal protein catabolic process
BH	0070062	cellular_component	extracellular exosome
BH	0071357	biological_process	cellular response to type I interferon
BH	0072539	biological_process	T-helper 17 cell differentiation
BH	0140756	molecular_function	structural constituent of proteasome
BH	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BH	1904813	cellular_component	ficolin-1-rich granule lumen
BH	1990111	cellular_component	spermatoproteasome complex
BH	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BI	0000502	cellular_component	proteasome complex
BI	0000932	cellular_component	P-body
BI	0002376	biological_process	immune system process
BI	0005515	molecular_function	protein binding
BI	0005634	cellular_component	nucleus
BI	0005654	cellular_component	nucleoplasm
BI	0005737	cellular_component	cytoplasm
BI	0005829	cellular_component	cytosol
BI	0005839	cellular_component	proteasome core complex
BI	0006281	biological_process	DNA repair
BI	0006915	biological_process	apoptotic process
BI	0006974	biological_process	DNA damage response
BI	0006979	biological_process	response to oxidative stress
BI	0007283	biological_process	spermatogenesis
BI	0008021	cellular_component	synaptic vesicle
BI	0010498	biological_process	proteasomal protein catabolic process
BI	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BI	0019773	cellular_component	proteasome core complex, alpha-subunit complex
BI	0030317	biological_process	flagellated sperm motility
BI	0032729	biological_process	positive regulation of type II interferon production
BI	0032743	biological_process	positive regulation of interleukin-2 production
BI	0032760	biological_process	positive regulation of tumor necrosis factor production
BI	0034341	biological_process	response to type II interferon
BI	0034515	cellular_component	proteasome storage granule
BI	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BI	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BI	0045061	biological_process	thymic T cell selection
BI	0045063	biological_process	T-helper 1 cell differentiation
BI	0045590	biological_process	negative regulation of regulatory T cell differentiation
BI	0051321	biological_process	meiotic cell cycle
BI	0061136	biological_process	regulation of proteasomal protein catabolic process
BI	0070062	cellular_component	extracellular exosome
BI	0071357	biological_process	cellular response to type I interferon
BI	0072539	biological_process	T-helper 17 cell differentiation
BI	0140756	molecular_function	structural constituent of proteasome
BI	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BI	1990111	cellular_component	spermatoproteasome complex
BI	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BJ	0000502	cellular_component	proteasome complex
BJ	0002376	biological_process	immune system process
BJ	0005515	molecular_function	protein binding
BJ	0005634	cellular_component	nucleus
BJ	0005654	cellular_component	nucleoplasm
BJ	0005737	cellular_component	cytoplasm
BJ	0005829	cellular_component	cytosol
BJ	0005839	cellular_component	proteasome core complex
BJ	0006281	biological_process	DNA repair
BJ	0006915	biological_process	apoptotic process
BJ	0006974	biological_process	DNA damage response
BJ	0006979	biological_process	response to oxidative stress
BJ	0008021	cellular_component	synaptic vesicle
BJ	0010498	biological_process	proteasomal protein catabolic process
BJ	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BJ	0019773	cellular_component	proteasome core complex, alpha-subunit complex
BJ	0030317	biological_process	flagellated sperm motility
BJ	0032729	biological_process	positive regulation of type II interferon production
BJ	0032743	biological_process	positive regulation of interleukin-2 production
BJ	0032760	biological_process	positive regulation of tumor necrosis factor production
BJ	0034341	biological_process	response to type II interferon
BJ	0034515	cellular_component	proteasome storage granule
BJ	0042802	molecular_function	identical protein binding
BJ	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BJ	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BJ	0045061	biological_process	thymic T cell selection
BJ	0045063	biological_process	T-helper 1 cell differentiation
BJ	0045590	biological_process	negative regulation of regulatory T cell differentiation
BJ	0061136	biological_process	regulation of proteasomal protein catabolic process
BJ	0070062	cellular_component	extracellular exosome
BJ	0071357	biological_process	cellular response to type I interferon
BJ	0072539	biological_process	T-helper 17 cell differentiation
BJ	0140756	molecular_function	structural constituent of proteasome
BJ	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BJ	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BK	0000502	cellular_component	proteasome complex
BK	0002376	biological_process	immune system process
BK	0005515	molecular_function	protein binding
BK	0005576	cellular_component	extracellular region
BK	0005634	cellular_component	nucleus
BK	0005654	cellular_component	nucleoplasm
BK	0005737	cellular_component	cytoplasm
BK	0005829	cellular_component	cytosol
BK	0005839	cellular_component	proteasome core complex
BK	0006281	biological_process	DNA repair
BK	0006915	biological_process	apoptotic process
BK	0006974	biological_process	DNA damage response
BK	0006979	biological_process	response to oxidative stress
BK	0007283	biological_process	spermatogenesis
BK	0008021	cellular_component	synaptic vesicle
BK	0010498	biological_process	proteasomal protein catabolic process
BK	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BK	0019773	cellular_component	proteasome core complex, alpha-subunit complex
BK	0030317	biological_process	flagellated sperm motility
BK	0032729	biological_process	positive regulation of type II interferon production
BK	0032743	biological_process	positive regulation of interleukin-2 production
BK	0032760	biological_process	positive regulation of tumor necrosis factor production
BK	0034341	biological_process	response to type II interferon
BK	0034515	cellular_component	proteasome storage granule
BK	0034774	cellular_component	secretory granule lumen
BK	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BK	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BK	0045061	biological_process	thymic T cell selection
BK	0045063	biological_process	T-helper 1 cell differentiation
BK	0045590	biological_process	negative regulation of regulatory T cell differentiation
BK	0051321	biological_process	meiotic cell cycle
BK	0061136	biological_process	regulation of proteasomal protein catabolic process
BK	0070062	cellular_component	extracellular exosome
BK	0071357	biological_process	cellular response to type I interferon
BK	0072539	biological_process	T-helper 17 cell differentiation
BK	0140756	molecular_function	structural constituent of proteasome
BK	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BK	1904813	cellular_component	ficolin-1-rich granule lumen
BK	1990111	cellular_component	spermatoproteasome complex
BK	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BL	0000502	cellular_component	proteasome complex
BL	0001530	molecular_function	lipopolysaccharide binding
BL	0002376	biological_process	immune system process
BL	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
BL	0005515	molecular_function	protein binding
BL	0005634	cellular_component	nucleus
BL	0005654	cellular_component	nucleoplasm
BL	0005737	cellular_component	cytoplasm
BL	0005829	cellular_component	cytosol
BL	0005839	cellular_component	proteasome core complex
BL	0006281	biological_process	DNA repair
BL	0006915	biological_process	apoptotic process
BL	0006974	biological_process	DNA damage response
BL	0006979	biological_process	response to oxidative stress
BL	0007283	biological_process	spermatogenesis
BL	0008021	cellular_component	synaptic vesicle
BL	0010498	biological_process	proteasomal protein catabolic process
BL	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BL	0016604	cellular_component	nuclear body
BL	0019773	cellular_component	proteasome core complex, alpha-subunit complex
BL	0030317	biological_process	flagellated sperm motility
BL	0032729	biological_process	positive regulation of type II interferon production
BL	0032743	biological_process	positive regulation of interleukin-2 production
BL	0032760	biological_process	positive regulation of tumor necrosis factor production
BL	0034341	biological_process	response to type II interferon
BL	0034515	cellular_component	proteasome storage granule
BL	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BL	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BL	0045061	biological_process	thymic T cell selection
BL	0045063	biological_process	T-helper 1 cell differentiation
BL	0045590	biological_process	negative regulation of regulatory T cell differentiation
BL	0051321	biological_process	meiotic cell cycle
BL	0061136	biological_process	regulation of proteasomal protein catabolic process
BL	0070062	cellular_component	extracellular exosome
BL	0071357	biological_process	cellular response to type I interferon
BL	0072539	biological_process	T-helper 17 cell differentiation
BL	0140756	molecular_function	structural constituent of proteasome
BL	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BL	1990111	cellular_component	spermatoproteasome complex
BL	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BM	0000502	cellular_component	proteasome complex
BM	0002376	biological_process	immune system process
BM	0005515	molecular_function	protein binding
BM	0005634	cellular_component	nucleus
BM	0005654	cellular_component	nucleoplasm
BM	0005737	cellular_component	cytoplasm
BM	0005829	cellular_component	cytosol
BM	0005839	cellular_component	proteasome core complex
BM	0006281	biological_process	DNA repair
BM	0006915	biological_process	apoptotic process
BM	0006974	biological_process	DNA damage response
BM	0006979	biological_process	response to oxidative stress
BM	0007283	biological_process	spermatogenesis
BM	0008021	cellular_component	synaptic vesicle
BM	0010498	biological_process	proteasomal protein catabolic process
BM	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BM	0019773	cellular_component	proteasome core complex, alpha-subunit complex
BM	0030317	biological_process	flagellated sperm motility
BM	0031625	molecular_function	ubiquitin protein ligase binding
BM	0032729	biological_process	positive regulation of type II interferon production
BM	0032743	biological_process	positive regulation of interleukin-2 production
BM	0032760	biological_process	positive regulation of tumor necrosis factor production
BM	0034341	biological_process	response to type II interferon
BM	0034515	cellular_component	proteasome storage granule
BM	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BM	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BM	0045061	biological_process	thymic T cell selection
BM	0045063	biological_process	T-helper 1 cell differentiation
BM	0045590	biological_process	negative regulation of regulatory T cell differentiation
BM	0051321	biological_process	meiotic cell cycle
BM	0061136	biological_process	regulation of proteasomal protein catabolic process
BM	0070062	cellular_component	extracellular exosome
BM	0071357	biological_process	cellular response to type I interferon
BM	0072539	biological_process	T-helper 17 cell differentiation
BM	0140756	molecular_function	structural constituent of proteasome
BM	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BM	1990111	cellular_component	spermatoproteasome complex
BM	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BN	0000502	cellular_component	proteasome complex
BN	0004175	molecular_function	endopeptidase activity
BN	0004298	molecular_function	threonine-type endopeptidase activity
BN	0005515	molecular_function	protein binding
BN	0005634	cellular_component	nucleus
BN	0005654	cellular_component	nucleoplasm
BN	0005737	cellular_component	cytoplasm
BN	0005829	cellular_component	cytosol
BN	0005839	cellular_component	proteasome core complex
BN	0006281	biological_process	DNA repair
BN	0006915	biological_process	apoptotic process
BN	0006974	biological_process	DNA damage response
BN	0006979	biological_process	response to oxidative stress
BN	0007283	biological_process	spermatogenesis
BN	0008021	cellular_component	synaptic vesicle
BN	0010498	biological_process	proteasomal protein catabolic process
BN	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BN	0019774	cellular_component	proteasome core complex, beta-subunit complex
BN	0030317	biological_process	flagellated sperm motility
BN	0034515	cellular_component	proteasome storage granule
BN	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BN	0045296	molecular_function	cadherin binding
BN	0051321	biological_process	meiotic cell cycle
BN	0061136	biological_process	regulation of proteasomal protein catabolic process
BN	0070062	cellular_component	extracellular exosome
BN	0071357	biological_process	cellular response to type I interferon
BN	1990111	cellular_component	spermatoproteasome complex
BN	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BO	0000502	cellular_component	proteasome complex
BO	0004175	molecular_function	endopeptidase activity
BO	0004298	molecular_function	threonine-type endopeptidase activity
BO	0005515	molecular_function	protein binding
BO	0005576	cellular_component	extracellular region
BO	0005634	cellular_component	nucleus
BO	0005654	cellular_component	nucleoplasm
BO	0005737	cellular_component	cytoplasm
BO	0005829	cellular_component	cytosol
BO	0005839	cellular_component	proteasome core complex
BO	0006281	biological_process	DNA repair
BO	0006915	biological_process	apoptotic process
BO	0006974	biological_process	DNA damage response
BO	0006979	biological_process	response to oxidative stress
BO	0007283	biological_process	spermatogenesis
BO	0008021	cellular_component	synaptic vesicle
BO	0010498	biological_process	proteasomal protein catabolic process
BO	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BO	0016604	cellular_component	nuclear body
BO	0019774	cellular_component	proteasome core complex, beta-subunit complex
BO	0030317	biological_process	flagellated sperm motility
BO	0034515	cellular_component	proteasome storage granule
BO	0034774	cellular_component	secretory granule lumen
BO	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BO	0051321	biological_process	meiotic cell cycle
BO	0061136	biological_process	regulation of proteasomal protein catabolic process
BO	0071357	biological_process	cellular response to type I interferon
BO	1904813	cellular_component	ficolin-1-rich granule lumen
BO	1990111	cellular_component	spermatoproteasome complex
BO	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BP	0000502	cellular_component	proteasome complex
BP	0002376	biological_process	immune system process
BP	0005515	molecular_function	protein binding
BP	0005634	cellular_component	nucleus
BP	0005654	cellular_component	nucleoplasm
BP	0005737	cellular_component	cytoplasm
BP	0005829	cellular_component	cytosol
BP	0005839	cellular_component	proteasome core complex
BP	0006281	biological_process	DNA repair
BP	0006915	biological_process	apoptotic process
BP	0006974	biological_process	DNA damage response
BP	0006979	biological_process	response to oxidative stress
BP	0007283	biological_process	spermatogenesis
BP	0008021	cellular_component	synaptic vesicle
BP	0010498	biological_process	proteasomal protein catabolic process
BP	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BP	0019774	cellular_component	proteasome core complex, beta-subunit complex
BP	0030317	biological_process	flagellated sperm motility
BP	0032729	biological_process	positive regulation of type II interferon production
BP	0032743	biological_process	positive regulation of interleukin-2 production
BP	0032760	biological_process	positive regulation of tumor necrosis factor production
BP	0034341	biological_process	response to type II interferon
BP	0034515	cellular_component	proteasome storage granule
BP	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BP	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BP	0045061	biological_process	thymic T cell selection
BP	0045063	biological_process	T-helper 1 cell differentiation
BP	0045590	biological_process	negative regulation of regulatory T cell differentiation
BP	0051321	biological_process	meiotic cell cycle
BP	0061136	biological_process	regulation of proteasomal protein catabolic process
BP	0070062	cellular_component	extracellular exosome
BP	0071357	biological_process	cellular response to type I interferon
BP	0072539	biological_process	T-helper 17 cell differentiation
BP	0140756	molecular_function	structural constituent of proteasome
BP	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BP	1990111	cellular_component	spermatoproteasome complex
BP	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BQ	0000502	cellular_component	proteasome complex
BQ	0002376	biological_process	immune system process
BQ	0005515	molecular_function	protein binding
BQ	0005634	cellular_component	nucleus
BQ	0005654	cellular_component	nucleoplasm
BQ	0005737	cellular_component	cytoplasm
BQ	0005829	cellular_component	cytosol
BQ	0005839	cellular_component	proteasome core complex
BQ	0006281	biological_process	DNA repair
BQ	0006915	biological_process	apoptotic process
BQ	0006974	biological_process	DNA damage response
BQ	0006979	biological_process	response to oxidative stress
BQ	0007283	biological_process	spermatogenesis
BQ	0008021	cellular_component	synaptic vesicle
BQ	0010498	biological_process	proteasomal protein catabolic process
BQ	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BQ	0016020	cellular_component	membrane
BQ	0019774	cellular_component	proteasome core complex, beta-subunit complex
BQ	0030317	biological_process	flagellated sperm motility
BQ	0032729	biological_process	positive regulation of type II interferon production
BQ	0032743	biological_process	positive regulation of interleukin-2 production
BQ	0032760	biological_process	positive regulation of tumor necrosis factor production
BQ	0034341	biological_process	response to type II interferon
BQ	0034515	cellular_component	proteasome storage granule
BQ	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BQ	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BQ	0045061	biological_process	thymic T cell selection
BQ	0045063	biological_process	T-helper 1 cell differentiation
BQ	0045590	biological_process	negative regulation of regulatory T cell differentiation
BQ	0051321	biological_process	meiotic cell cycle
BQ	0061136	biological_process	regulation of proteasomal protein catabolic process
BQ	0070062	cellular_component	extracellular exosome
BQ	0071357	biological_process	cellular response to type I interferon
BQ	0072539	biological_process	T-helper 17 cell differentiation
BQ	0140756	molecular_function	structural constituent of proteasome
BQ	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BQ	1990111	cellular_component	spermatoproteasome complex
BQ	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BR	0000502	cellular_component	proteasome complex
BR	0004175	molecular_function	endopeptidase activity
BR	0004298	molecular_function	threonine-type endopeptidase activity
BR	0005515	molecular_function	protein binding
BR	0005634	cellular_component	nucleus
BR	0005654	cellular_component	nucleoplasm
BR	0005737	cellular_component	cytoplasm
BR	0005829	cellular_component	cytosol
BR	0005839	cellular_component	proteasome core complex
BR	0006281	biological_process	DNA repair
BR	0006508	biological_process	proteolysis
BR	0006915	biological_process	apoptotic process
BR	0006974	biological_process	DNA damage response
BR	0006979	biological_process	response to oxidative stress
BR	0007283	biological_process	spermatogenesis
BR	0008021	cellular_component	synaptic vesicle
BR	0008233	molecular_function	peptidase activity
BR	0010498	biological_process	proteasomal protein catabolic process
BR	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BR	0019774	cellular_component	proteasome core complex, beta-subunit complex
BR	0030317	biological_process	flagellated sperm motility
BR	0034515	cellular_component	proteasome storage granule
BR	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BR	0043248	biological_process	proteasome assembly
BR	0051321	biological_process	meiotic cell cycle
BR	0061136	biological_process	regulation of proteasomal protein catabolic process
BR	0070062	cellular_component	extracellular exosome
BR	0071357	biological_process	cellular response to type I interferon
BR	1990111	cellular_component	spermatoproteasome complex
BR	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BS	0000502	cellular_component	proteasome complex
BS	0002376	biological_process	immune system process
BS	0005515	molecular_function	protein binding
BS	0005576	cellular_component	extracellular region
BS	0005634	cellular_component	nucleus
BS	0005654	cellular_component	nucleoplasm
BS	0005737	cellular_component	cytoplasm
BS	0005829	cellular_component	cytosol
BS	0005839	cellular_component	proteasome core complex
BS	0006281	biological_process	DNA repair
BS	0006915	biological_process	apoptotic process
BS	0006974	biological_process	DNA damage response
BS	0006979	biological_process	response to oxidative stress
BS	0007283	biological_process	spermatogenesis
BS	0008021	cellular_component	synaptic vesicle
BS	0010498	biological_process	proteasomal protein catabolic process
BS	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BS	0019774	cellular_component	proteasome core complex, beta-subunit complex
BS	0030317	biological_process	flagellated sperm motility
BS	0032729	biological_process	positive regulation of type II interferon production
BS	0032743	biological_process	positive regulation of interleukin-2 production
BS	0032760	biological_process	positive regulation of tumor necrosis factor production
BS	0034341	biological_process	response to type II interferon
BS	0034515	cellular_component	proteasome storage granule
BS	0034774	cellular_component	secretory granule lumen
BS	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BS	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BS	0045061	biological_process	thymic T cell selection
BS	0045063	biological_process	T-helper 1 cell differentiation
BS	0045590	biological_process	negative regulation of regulatory T cell differentiation
BS	0051321	biological_process	meiotic cell cycle
BS	0061136	biological_process	regulation of proteasomal protein catabolic process
BS	0070062	cellular_component	extracellular exosome
BS	0071357	biological_process	cellular response to type I interferon
BS	0072539	biological_process	T-helper 17 cell differentiation
BS	0140756	molecular_function	structural constituent of proteasome
BS	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BS	1904813	cellular_component	ficolin-1-rich granule lumen
BS	1990111	cellular_component	spermatoproteasome complex
BS	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BT	0000502	cellular_component	proteasome complex
BT	0001530	molecular_function	lipopolysaccharide binding
BT	0002376	biological_process	immune system process
BT	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
BT	0005515	molecular_function	protein binding
BT	0005634	cellular_component	nucleus
BT	0005654	cellular_component	nucleoplasm
BT	0005737	cellular_component	cytoplasm
BT	0005829	cellular_component	cytosol
BT	0005839	cellular_component	proteasome core complex
BT	0006281	biological_process	DNA repair
BT	0006915	biological_process	apoptotic process
BT	0006974	biological_process	DNA damage response
BT	0006979	biological_process	response to oxidative stress
BT	0007283	biological_process	spermatogenesis
BT	0008021	cellular_component	synaptic vesicle
BT	0010498	biological_process	proteasomal protein catabolic process
BT	0010499	biological_process	proteasomal ubiquitin-independent protein catabolic process
BT	0019774	cellular_component	proteasome core complex, beta-subunit complex
BT	0030317	biological_process	flagellated sperm motility
BT	0032729	biological_process	positive regulation of type II interferon production
BT	0032743	biological_process	positive regulation of interleukin-2 production
BT	0032760	biological_process	positive regulation of tumor necrosis factor production
BT	0034341	biological_process	response to type II interferon
BT	0034515	cellular_component	proteasome storage granule
BT	0036064	cellular_component	ciliary basal body
BT	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BT	0043374	biological_process	CD8-positive, alpha-beta T cell differentiation
BT	0045061	biological_process	thymic T cell selection
BT	0045063	biological_process	T-helper 1 cell differentiation
BT	0045590	biological_process	negative regulation of regulatory T cell differentiation
BT	0051321	biological_process	meiotic cell cycle
BT	0061136	biological_process	regulation of proteasomal protein catabolic process
BT	0070062	cellular_component	extracellular exosome
BT	0071357	biological_process	cellular response to type I interferon
BT	0072539	biological_process	T-helper 17 cell differentiation
BT	0140756	molecular_function	structural constituent of proteasome
BT	0160165	biological_process	CD8-positive, alpha-beta T cell homeostasis
BT	1990111	cellular_component	spermatoproteasome complex
BT	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
BU	0000502	cellular_component	proteasome complex
BU	0005515	molecular_function	protein binding
BU	0005576	cellular_component	extracellular region
BU	0005654	cellular_component	nucleoplasm
BU	0005829	cellular_component	cytosol
BU	0005838	cellular_component	proteasome regulatory particle
BU	0006979	biological_process	response to oxidative stress
BU	0008021	cellular_component	synaptic vesicle
BU	0010498	biological_process	proteasomal protein catabolic process
BU	0016020	cellular_component	membrane
BU	0022624	cellular_component	proteasome accessory complex
BU	0031625	molecular_function	ubiquitin protein ligase binding
BU	0034515	cellular_component	proteasome storage granule
BU	0035578	cellular_component	azurophil granule lumen
BU	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BU	0061136	biological_process	regulation of proteasomal protein catabolic process
BU	0071357	biological_process	cellular response to type I interferon
BV	0000502	cellular_component	proteasome complex
BV	0005515	molecular_function	protein binding
BV	0005576	cellular_component	extracellular region
BV	0005634	cellular_component	nucleus
BV	0005654	cellular_component	nucleoplasm
BV	0005829	cellular_component	cytosol
BV	0005838	cellular_component	proteasome regulatory particle
BV	0006511	biological_process	ubiquitin-dependent protein catabolic process
BV	0006979	biological_process	response to oxidative stress
BV	0008021	cellular_component	synaptic vesicle
BV	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
BV	0010498	biological_process	proteasomal protein catabolic process
BV	0016020	cellular_component	membrane
BV	0022624	cellular_component	proteasome accessory complex
BV	0034774	cellular_component	secretory granule lumen
BV	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BV	0061136	biological_process	regulation of proteasomal protein catabolic process
BV	0070062	cellular_component	extracellular exosome
BV	0071357	biological_process	cellular response to type I interferon
BV	1904813	cellular_component	ficolin-1-rich granule lumen
BW	0000502	cellular_component	proteasome complex
BW	0005515	molecular_function	protein binding
BW	0005576	cellular_component	extracellular region
BW	0005654	cellular_component	nucleoplasm
BW	0005829	cellular_component	cytosol
BW	0005838	cellular_component	proteasome regulatory particle
BW	0006979	biological_process	response to oxidative stress
BW	0008021	cellular_component	synaptic vesicle
BW	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
BW	0010498	biological_process	proteasomal protein catabolic process
BW	0016020	cellular_component	membrane
BW	0022624	cellular_component	proteasome accessory complex
BW	0034774	cellular_component	secretory granule lumen
BW	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BW	0061136	biological_process	regulation of proteasomal protein catabolic process
BW	0070062	cellular_component	extracellular exosome
BW	0071357	biological_process	cellular response to type I interferon
BW	1904813	cellular_component	ficolin-1-rich granule lumen
BX	0000502	cellular_component	proteasome complex
BX	0005198	molecular_function	structural molecule activity
BX	0005515	molecular_function	protein binding
BX	0005576	cellular_component	extracellular region
BX	0005634	cellular_component	nucleus
BX	0005654	cellular_component	nucleoplasm
BX	0005829	cellular_component	cytosol
BX	0005838	cellular_component	proteasome regulatory particle
BX	0006511	biological_process	ubiquitin-dependent protein catabolic process
BX	0006979	biological_process	response to oxidative stress
BX	0008021	cellular_component	synaptic vesicle
BX	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
BX	0010498	biological_process	proteasomal protein catabolic process
BX	0016020	cellular_component	membrane
BX	0022624	cellular_component	proteasome accessory complex
BX	0032991	cellular_component	protein-containing complex
BX	0034774	cellular_component	secretory granule lumen
BX	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BX	0043248	biological_process	proteasome assembly
BX	0048863	biological_process	stem cell differentiation
BX	0061136	biological_process	regulation of proteasomal protein catabolic process
BX	0071357	biological_process	cellular response to type I interferon
BX	1904813	cellular_component	ficolin-1-rich granule lumen
BY	0000502	cellular_component	proteasome complex
BY	0005515	molecular_function	protein binding
BY	0005576	cellular_component	extracellular region
BY	0005654	cellular_component	nucleoplasm
BY	0005829	cellular_component	cytosol
BY	0005838	cellular_component	proteasome regulatory particle
BY	0006979	biological_process	response to oxidative stress
BY	0008021	cellular_component	synaptic vesicle
BY	0010498	biological_process	proteasomal protein catabolic process
BY	0022624	cellular_component	proteasome accessory complex
BY	0032991	cellular_component	protein-containing complex
BY	0034774	cellular_component	secretory granule lumen
BY	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BY	0061136	biological_process	regulation of proteasomal protein catabolic process
BY	0071357	biological_process	cellular response to type I interferon
BY	1904813	cellular_component	ficolin-1-rich granule lumen
BZ	0000502	cellular_component	proteasome complex
BZ	0005515	molecular_function	protein binding
BZ	0005576	cellular_component	extracellular region
BZ	0005634	cellular_component	nucleus
BZ	0005654	cellular_component	nucleoplasm
BZ	0005829	cellular_component	cytosol
BZ	0005838	cellular_component	proteasome regulatory particle
BZ	0006979	biological_process	response to oxidative stress
BZ	0008021	cellular_component	synaptic vesicle
BZ	0008233	molecular_function	peptidase activity
BZ	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
BZ	0010498	biological_process	proteasomal protein catabolic process
BZ	0016020	cellular_component	membrane
BZ	0034774	cellular_component	secretory granule lumen
BZ	0042803	molecular_function	protein homodimerization activity
BZ	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
BZ	0061136	biological_process	regulation of proteasomal protein catabolic process
BZ	0070062	cellular_component	extracellular exosome
BZ	0071357	biological_process	cellular response to type I interferon
BZ	0140492	molecular_function	metal-dependent deubiquitinase activity
BZ	1904813	cellular_component	ficolin-1-rich granule lumen

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. AAGFSSSGPAATSGAV

Chain	Residue	Details
Ad	ALA-21-VAL-6

---

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
Au	LYS27-ASP52

---

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. FdrhiTiFSPeGRlyQVEYAfkA

Chain	Residue	Details
AG	PHE9-ALA31
AK	TYR8-ALA30
AJ	TYR3-ALA25
AM	TYR7-ALA29
AL	TYR6-ALA28
AH	TYR6-ALA28
AI	TYR5-ALA27

---

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. VkVImATNradtLDpALl.R

Chain	Residue	Details
AD	VAL305-ARG323
AA	ILE315-ARG333
AF	VAL326-ARG344
AC	ILE289-ARG307
AB	VAL325-ARG343
AE	VAL273-ARG291

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. MAMkGknCVAIAADrrfgiqaqmvttdfq.KifpmgdrlyiglaGlaTD

Chain	Residue	Details
AP	MET12-ASP59
BS	LEU13-ASP60
AO	ALA4-ASP51
AN	MET4-ASP51
AR	LEU4-ASP51
AQ	ILE5-ASP52
AI	LEU35-ASP82
BT	LEU12-ASP59

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	46
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	124
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	128
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"17370265","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	38
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9QUM9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	10
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P49722","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P17220","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1 and ABL2","evidences":[{"source":"PubMed","id":"16678104","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; alternate","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine; alternate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	10
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"25599644","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27493187","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	6
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","von Kriegsheim A.F.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18502982","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18565852","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19426847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O09061","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	132
Details	Repeat: {"description":"PC 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	138
Details	Repeat: {"description":"PC 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	136
Details	Repeat: {"description":"PC 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	136
Details	Repeat: {"description":"PC 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	124
Details	Repeat: {"description":"PC 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	132
Details	Repeat: {"description":"PC 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	94
Details	Repeat: {"description":"PC 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	68
Details	Repeat: {"description":"PC 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	80
Details	Repeat: {"description":"PC 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	64
Details	Repeat: {"description":"PC 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q3TXS7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	2058
Details	Domain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	2
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Potts A.","Brablan J.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	540
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	366
Details	Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	26
Details	Motif: {"description":"JAMM motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17693683","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	390
Details	Region: {"description":"Required for interaction with UBLCP1","evidences":[{"source":"PubMed","id":"28539385","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"17323924","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8VDM4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI68
Number of Residues	300
Details	Domain: {"description":"Ubiquitin-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI69
Number of Residues	8
Details	Site: {"description":"Interacts with activating enzyme"}

Chain

Residue

Details

---

site_id	SWS_FT_FI70
Number of Residues	4
Details	Site: {"description":"Essential for function"}

Chain

Residue

Details

---

site_id	SWS_FT_FI71
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by PINK1","evidences":[{"source":"PubMed","id":"24660806","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24751536","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24784582","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25527291","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI72
Number of Residues	4
Details	Modified residue: {"description":"(Microbial infection) ADP-ribosylthreonine","evidences":[{"source":"PubMed","id":"32330457","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI73
Number of Residues	4
Details	Modified residue: {"description":"ADP-ribosylglycine","evidences":[{"source":"PubMed","id":"28525742","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI74
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"16443603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI76
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"16443603","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16543144","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"15466860","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI78
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"16543144","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25752573","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25752577","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34239127","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"25752577","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"16543144","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18719106","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---