9K20
Cryo-EM structure of ATP-bound P2Y purinoceptor 2-miniGo-scFv16 complex
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. CSIlFLTCISVHRCLgV |
| Chain | Residue | Details |
| A | CYS119-VAL135 |
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS |
| Chain | Residue | Details |
| C | LEU70-SER84 | |
| C | ILE157-ILE171 | |
| C | LEU285-ALA299 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| D | ALA2 | |
| B | GLY43 | |
| B | LYS44 | |
| B | SER45 | |
| B | THR64 | |
| B | LYS152 | |
| B | PRO155 | |
| B | ILE207 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Cysteine methyl ester => ECO:0000250|UniProtKB:P63212 |
| Chain | Residue | Details |
| D | CYS68 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | LIPID: S-geranylgeranyl cysteine => ECO:0000250|UniProtKB:P63212 |
| Chain | Residue | Details |
| D | CYS68 | |
| A | HIS130-ARG152 | |
| A | MET221-THR246 | |
| A | GLY310-LEU377 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:33408414 |
| Chain | Residue | Details |
| A | TYR71-TYR93 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE111-VAL129 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL153-VAL172 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE195-LEU220 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE247-TYR269 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | TYR288-ALA309 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN9 | |
| A | ASN13 |
