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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9JXV

human translocase of the outer mitochondrial membrane (TOM complex)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005739cellular_componentmitochondrion
A0005741cellular_componentmitochondrial outer membrane
A0005742cellular_componentmitochondrial outer membrane translocase complex
A0005743cellular_componentmitochondrial inner membrane
A0008320molecular_functionprotein transmembrane transporter activity
A0016020cellular_componentmembrane
A0030150biological_processprotein import into mitochondrial matrix
A0030943molecular_functionmitochondrion targeting sequence binding
A0044233cellular_componentmitochondria-associated endoplasmic reticulum membrane contact site
A0045040biological_processprotein insertion into mitochondrial outer membrane
A0055085biological_processtransmembrane transport
A0070585biological_processprotein localization to mitochondrion
B0005515molecular_functionprotein binding
B0005739cellular_componentmitochondrion
B0005741cellular_componentmitochondrial outer membrane
B0005742cellular_componentmitochondrial outer membrane translocase complex
B0005743cellular_componentmitochondrial inner membrane
B0008320molecular_functionprotein transmembrane transporter activity
B0016020cellular_componentmembrane
B0030150biological_processprotein import into mitochondrial matrix
B0030943molecular_functionmitochondrion targeting sequence binding
B0044233cellular_componentmitochondria-associated endoplasmic reticulum membrane contact site
B0045040biological_processprotein insertion into mitochondrial outer membrane
B0055085biological_processtransmembrane transport
B0070585biological_processprotein localization to mitochondrion
C0005515molecular_functionprotein binding
C0005739cellular_componentmitochondrion
C0005741cellular_componentmitochondrial outer membrane
C0005742cellular_componentmitochondrial outer membrane translocase complex
C0006886biological_processintracellular protein transport
C0008320molecular_functionprotein transmembrane transporter activity
C0016020cellular_componentmembrane
C0030150biological_processprotein import into mitochondrial matrix
C0030943molecular_functionmitochondrion targeting sequence binding
C0045040biological_processprotein insertion into mitochondrial outer membrane
C0070585biological_processprotein localization to mitochondrion
D0005515molecular_functionprotein binding
D0005739cellular_componentmitochondrion
D0005741cellular_componentmitochondrial outer membrane
D0005742cellular_componentmitochondrial outer membrane translocase complex
D0006886biological_processintracellular protein transport
D0008320molecular_functionprotein transmembrane transporter activity
D0016020cellular_componentmembrane
D0030150biological_processprotein import into mitochondrial matrix
D0030943molecular_functionmitochondrion targeting sequence binding
D0045040biological_processprotein insertion into mitochondrial outer membrane
D0070585biological_processprotein localization to mitochondrion
E0005515molecular_functionprotein binding
E0005739cellular_componentmitochondrion
E0005741cellular_componentmitochondrial outer membrane
E0005742cellular_componentmitochondrial outer membrane translocase complex
E0045040biological_processprotein insertion into mitochondrial outer membrane
F0005515molecular_functionprotein binding
F0005739cellular_componentmitochondrion
F0005741cellular_componentmitochondrial outer membrane
F0005742cellular_componentmitochondrial outer membrane translocase complex
F0045040biological_processprotein insertion into mitochondrial outer membrane
G0005515molecular_functionprotein binding
G0005739cellular_componentmitochondrion
G0005741cellular_componentmitochondrial outer membrane
G0005742cellular_componentmitochondrial outer membrane translocase complex
G0008320molecular_functionprotein transmembrane transporter activity
G0030150biological_processprotein import into mitochondrial matrix
G0031647biological_processregulation of protein stability
G0045040biological_processprotein insertion into mitochondrial outer membrane
G1903749biological_processpositive regulation of protein localization to mitochondrion
G1905091biological_processpositive regulation of type 2 mitophagy
H0005515molecular_functionprotein binding
H0005739cellular_componentmitochondrion
H0005741cellular_componentmitochondrial outer membrane
H0005742cellular_componentmitochondrial outer membrane translocase complex
H0008320molecular_functionprotein transmembrane transporter activity
H0030150biological_processprotein import into mitochondrial matrix
H0031647biological_processregulation of protein stability
H0045040biological_processprotein insertion into mitochondrial outer membrane
H1903749biological_processpositive regulation of protein localization to mitochondrion
H1905091biological_processpositive regulation of type 2 mitophagy
I0005739cellular_componentmitochondrion
I0005741cellular_componentmitochondrial outer membrane
I0005742cellular_componentmitochondrial outer membrane translocase complex
I0045040biological_processprotein insertion into mitochondrial outer membrane
I0070585biological_processprotein localization to mitochondrion
J0005739cellular_componentmitochondrion
J0005741cellular_componentmitochondrial outer membrane
J0005742cellular_componentmitochondrial outer membrane translocase complex
J0045040biological_processprotein insertion into mitochondrial outer membrane
J0070585biological_processprotein localization to mitochondrion
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues46
DetailsIntramembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"40080546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EIJ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues236
DetailsTransmembrane: {"description":"Beta stranded","evidences":[{"source":"PubMed","id":"40080546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EIJ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues116
DetailsTopological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"40080546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EIJ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues98
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"40080546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EIJ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues180
DetailsTransmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"40080546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EIJ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues40
DetailsRegion: {"description":"TMD; necessary for mitochondrion outer membrane localization and integration in the TOM complex","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues36
DetailsTopological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"12198123","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"40080546","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9EIJ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

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PDB entries from 2026-03-25

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