9JTO
Human glucose 6 phosphate catalytic subunit 1 (hG6PC1) bound with F6P.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004346 | molecular_function | glucose-6-phosphatase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005977 | biological_process | glycogen metabolic process |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0009743 | biological_process | response to carbohydrate |
| A | 0016020 | cellular_component | membrane |
| A | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0031667 | biological_process | response to nutrient levels |
| A | 0032094 | biological_process | response to food |
| A | 0032868 | biological_process | response to insulin |
| A | 0032869 | biological_process | cellular response to insulin stimulus |
| A | 0042301 | molecular_function | phosphate ion binding |
| A | 0042593 | biological_process | glucose homeostasis |
| A | 0048878 | biological_process | chemical homeostasis |
| A | 0051156 | biological_process | glucose 6-phosphate metabolic process |
| A | 0055088 | biological_process | lipid homeostasis |
| A | 1904638 | biological_process | response to resveratrol |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 102 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"9497333","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 182 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 31 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"9497333","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"12093795","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9497333","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9705299","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
