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9JP0

the wild-type human PRMT1 filament

Functional Information from GO Data
ChainGOidnamespacecontents
A0001701biological_processin utero embryonic development
A0003723molecular_functionRNA binding
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005765cellular_componentlysosomal membrane
A0005829cellular_componentcytosol
A0006338biological_processchromatin remodeling
A0006355biological_processregulation of DNA-templated transcription
A0006479biological_processprotein methylation
A0006974biological_processDNA damage response
A0007166biological_processcell surface receptor signaling pathway
A0008168molecular_functionmethyltransferase activity
A0008170molecular_functionN-methyltransferase activity
A0008276molecular_functionprotein methyltransferase activity
A0008284biological_processpositive regulation of cell population proliferation
A0008327molecular_functionmethyl-CpG binding
A0008380biological_processRNA splicing
A0016274molecular_functionprotein-arginine N-methyltransferase activity
A0016740molecular_functiontransferase activity
A0018216biological_processpeptidyl-arginine methylation
A0019082biological_processviral protein processing
A0019899molecular_functionenzyme binding
A0030510biological_processregulation of BMP signaling pathway
A0031175biological_processneuron projection development
A0032259biological_processmethylation
A0034709cellular_componentmethylosome
A0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
A0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
A0042054molecular_functionhistone methyltransferase activity
A0042802molecular_functionidentical protein binding
A0043066biological_processnegative regulation of apoptotic process
A0044020molecular_functionhistone H4R3 methyltransferase activity
A0045648biological_processpositive regulation of erythrocyte differentiation
A0045652biological_processregulation of megakaryocyte differentiation
A0045653biological_processnegative regulation of megakaryocyte differentiation
A0045727biological_processpositive regulation of translation
A0046329biological_processnegative regulation of JNK cascade
A0046985biological_processpositive regulation of hemoglobin biosynthetic process
A0048273molecular_functionmitogen-activated protein kinase p38 binding
A0048738biological_processcardiac muscle tissue development
A0051260biological_processprotein homooligomerization
A0061431biological_processcellular response to methionine
A0106080molecular_functionGATOR1 complex binding
A0140939molecular_functionhistone H4 methyltransferase activity
A1900745biological_processpositive regulation of p38MAPK cascade
A1904047molecular_functionS-adenosyl-L-methionine binding
A1904263biological_processpositive regulation of TORC1 signaling
A1905168biological_processpositive regulation of double-strand break repair via homologous recombination
B0001701biological_processin utero embryonic development
B0003723molecular_functionRNA binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005765cellular_componentlysosomal membrane
B0005829cellular_componentcytosol
B0006338biological_processchromatin remodeling
B0006355biological_processregulation of DNA-templated transcription
B0006479biological_processprotein methylation
B0006974biological_processDNA damage response
B0007166biological_processcell surface receptor signaling pathway
B0008168molecular_functionmethyltransferase activity
B0008170molecular_functionN-methyltransferase activity
B0008276molecular_functionprotein methyltransferase activity
B0008284biological_processpositive regulation of cell population proliferation
B0008327molecular_functionmethyl-CpG binding
B0008380biological_processRNA splicing
B0016274molecular_functionprotein-arginine N-methyltransferase activity
B0016740molecular_functiontransferase activity
B0018216biological_processpeptidyl-arginine methylation
B0019082biological_processviral protein processing
B0019899molecular_functionenzyme binding
B0030510biological_processregulation of BMP signaling pathway
B0031175biological_processneuron projection development
B0032259biological_processmethylation
B0034709cellular_componentmethylosome
B0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
B0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
B0042054molecular_functionhistone methyltransferase activity
B0042802molecular_functionidentical protein binding
B0043066biological_processnegative regulation of apoptotic process
B0044020molecular_functionhistone H4R3 methyltransferase activity
B0045648biological_processpositive regulation of erythrocyte differentiation
B0045652biological_processregulation of megakaryocyte differentiation
B0045653biological_processnegative regulation of megakaryocyte differentiation
B0045727biological_processpositive regulation of translation
B0046329biological_processnegative regulation of JNK cascade
B0046985biological_processpositive regulation of hemoglobin biosynthetic process
B0048273molecular_functionmitogen-activated protein kinase p38 binding
B0048738biological_processcardiac muscle tissue development
B0051260biological_processprotein homooligomerization
B0061431biological_processcellular response to methionine
B0106080molecular_functionGATOR1 complex binding
B0140939molecular_functionhistone H4 methyltransferase activity
B1900745biological_processpositive regulation of p38MAPK cascade
B1904047molecular_functionS-adenosyl-L-methionine binding
B1904263biological_processpositive regulation of TORC1 signaling
B1905168biological_processpositive regulation of double-strand break repair via homologous recombination
C0001701biological_processin utero embryonic development
C0003723molecular_functionRNA binding
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005765cellular_componentlysosomal membrane
C0005829cellular_componentcytosol
C0006338biological_processchromatin remodeling
C0006355biological_processregulation of DNA-templated transcription
C0006479biological_processprotein methylation
C0006974biological_processDNA damage response
C0007166biological_processcell surface receptor signaling pathway
C0008168molecular_functionmethyltransferase activity
C0008170molecular_functionN-methyltransferase activity
C0008276molecular_functionprotein methyltransferase activity
C0008284biological_processpositive regulation of cell population proliferation
C0008327molecular_functionmethyl-CpG binding
C0008380biological_processRNA splicing
C0016274molecular_functionprotein-arginine N-methyltransferase activity
C0016740molecular_functiontransferase activity
C0018216biological_processpeptidyl-arginine methylation
C0019082biological_processviral protein processing
C0019899molecular_functionenzyme binding
C0030510biological_processregulation of BMP signaling pathway
C0031175biological_processneuron projection development
C0032259biological_processmethylation
C0034709cellular_componentmethylosome
C0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
C0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
C0042054molecular_functionhistone methyltransferase activity
C0042802molecular_functionidentical protein binding
C0043066biological_processnegative regulation of apoptotic process
C0044020molecular_functionhistone H4R3 methyltransferase activity
C0045648biological_processpositive regulation of erythrocyte differentiation
C0045652biological_processregulation of megakaryocyte differentiation
C0045653biological_processnegative regulation of megakaryocyte differentiation
C0045727biological_processpositive regulation of translation
C0046329biological_processnegative regulation of JNK cascade
C0046985biological_processpositive regulation of hemoglobin biosynthetic process
C0048273molecular_functionmitogen-activated protein kinase p38 binding
C0048738biological_processcardiac muscle tissue development
C0051260biological_processprotein homooligomerization
C0061431biological_processcellular response to methionine
C0106080molecular_functionGATOR1 complex binding
C0140939molecular_functionhistone H4 methyltransferase activity
C1900745biological_processpositive regulation of p38MAPK cascade
C1904047molecular_functionS-adenosyl-L-methionine binding
C1904263biological_processpositive regulation of TORC1 signaling
C1905168biological_processpositive regulation of double-strand break repair via homologous recombination
D0001701biological_processin utero embryonic development
D0003723molecular_functionRNA binding
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005765cellular_componentlysosomal membrane
D0005829cellular_componentcytosol
D0006338biological_processchromatin remodeling
D0006355biological_processregulation of DNA-templated transcription
D0006479biological_processprotein methylation
D0006974biological_processDNA damage response
D0007166biological_processcell surface receptor signaling pathway
D0008168molecular_functionmethyltransferase activity
D0008170molecular_functionN-methyltransferase activity
D0008276molecular_functionprotein methyltransferase activity
D0008284biological_processpositive regulation of cell population proliferation
D0008327molecular_functionmethyl-CpG binding
D0008380biological_processRNA splicing
D0016274molecular_functionprotein-arginine N-methyltransferase activity
D0016740molecular_functiontransferase activity
D0018216biological_processpeptidyl-arginine methylation
D0019082biological_processviral protein processing
D0019899molecular_functionenzyme binding
D0030510biological_processregulation of BMP signaling pathway
D0031175biological_processneuron projection development
D0032259biological_processmethylation
D0034709cellular_componentmethylosome
D0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
D0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
D0042054molecular_functionhistone methyltransferase activity
D0042802molecular_functionidentical protein binding
D0043066biological_processnegative regulation of apoptotic process
D0044020molecular_functionhistone H4R3 methyltransferase activity
D0045648biological_processpositive regulation of erythrocyte differentiation
D0045652biological_processregulation of megakaryocyte differentiation
D0045653biological_processnegative regulation of megakaryocyte differentiation
D0045727biological_processpositive regulation of translation
D0046329biological_processnegative regulation of JNK cascade
D0046985biological_processpositive regulation of hemoglobin biosynthetic process
D0048273molecular_functionmitogen-activated protein kinase p38 binding
D0048738biological_processcardiac muscle tissue development
D0051260biological_processprotein homooligomerization
D0061431biological_processcellular response to methionine
D0106080molecular_functionGATOR1 complex binding
D0140939molecular_functionhistone H4 methyltransferase activity
D1900745biological_processpositive regulation of p38MAPK cascade
D1904047molecular_functionS-adenosyl-L-methionine binding
D1904263biological_processpositive regulation of TORC1 signaling
D1905168biological_processpositive regulation of double-strand break repair via homologous recombination
E0001701biological_processin utero embryonic development
E0003723molecular_functionRNA binding
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005737cellular_componentcytoplasm
E0005765cellular_componentlysosomal membrane
E0005829cellular_componentcytosol
E0006338biological_processchromatin remodeling
E0006355biological_processregulation of DNA-templated transcription
E0006479biological_processprotein methylation
E0006974biological_processDNA damage response
E0007166biological_processcell surface receptor signaling pathway
E0008168molecular_functionmethyltransferase activity
E0008170molecular_functionN-methyltransferase activity
E0008276molecular_functionprotein methyltransferase activity
E0008284biological_processpositive regulation of cell population proliferation
E0008327molecular_functionmethyl-CpG binding
E0008380biological_processRNA splicing
E0016274molecular_functionprotein-arginine N-methyltransferase activity
E0016740molecular_functiontransferase activity
E0018216biological_processpeptidyl-arginine methylation
E0019082biological_processviral protein processing
E0019899molecular_functionenzyme binding
E0030510biological_processregulation of BMP signaling pathway
E0031175biological_processneuron projection development
E0032259biological_processmethylation
E0034709cellular_componentmethylosome
E0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
E0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
E0042054molecular_functionhistone methyltransferase activity
E0042802molecular_functionidentical protein binding
E0043066biological_processnegative regulation of apoptotic process
E0044020molecular_functionhistone H4R3 methyltransferase activity
E0045648biological_processpositive regulation of erythrocyte differentiation
E0045652biological_processregulation of megakaryocyte differentiation
E0045653biological_processnegative regulation of megakaryocyte differentiation
E0045727biological_processpositive regulation of translation
E0046329biological_processnegative regulation of JNK cascade
E0046985biological_processpositive regulation of hemoglobin biosynthetic process
E0048273molecular_functionmitogen-activated protein kinase p38 binding
E0048738biological_processcardiac muscle tissue development
E0051260biological_processprotein homooligomerization
E0061431biological_processcellular response to methionine
E0106080molecular_functionGATOR1 complex binding
E0140939molecular_functionhistone H4 methyltransferase activity
E1900745biological_processpositive regulation of p38MAPK cascade
E1904047molecular_functionS-adenosyl-L-methionine binding
E1904263biological_processpositive regulation of TORC1 signaling
E1905168biological_processpositive regulation of double-strand break repair via homologous recombination
F0001701biological_processin utero embryonic development
F0003723molecular_functionRNA binding
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005765cellular_componentlysosomal membrane
F0005829cellular_componentcytosol
F0006338biological_processchromatin remodeling
F0006355biological_processregulation of DNA-templated transcription
F0006479biological_processprotein methylation
F0006974biological_processDNA damage response
F0007166biological_processcell surface receptor signaling pathway
F0008168molecular_functionmethyltransferase activity
F0008170molecular_functionN-methyltransferase activity
F0008276molecular_functionprotein methyltransferase activity
F0008284biological_processpositive regulation of cell population proliferation
F0008327molecular_functionmethyl-CpG binding
F0008380biological_processRNA splicing
F0016274molecular_functionprotein-arginine N-methyltransferase activity
F0016740molecular_functiontransferase activity
F0018216biological_processpeptidyl-arginine methylation
F0019082biological_processviral protein processing
F0019899molecular_functionenzyme binding
F0030510biological_processregulation of BMP signaling pathway
F0031175biological_processneuron projection development
F0032259biological_processmethylation
F0034709cellular_componentmethylosome
F0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
F0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
F0042054molecular_functionhistone methyltransferase activity
F0042802molecular_functionidentical protein binding
F0043066biological_processnegative regulation of apoptotic process
F0044020molecular_functionhistone H4R3 methyltransferase activity
F0045648biological_processpositive regulation of erythrocyte differentiation
F0045652biological_processregulation of megakaryocyte differentiation
F0045653biological_processnegative regulation of megakaryocyte differentiation
F0045727biological_processpositive regulation of translation
F0046329biological_processnegative regulation of JNK cascade
F0046985biological_processpositive regulation of hemoglobin biosynthetic process
F0048273molecular_functionmitogen-activated protein kinase p38 binding
F0048738biological_processcardiac muscle tissue development
F0051260biological_processprotein homooligomerization
F0061431biological_processcellular response to methionine
F0106080molecular_functionGATOR1 complex binding
F0140939molecular_functionhistone H4 methyltransferase activity
F1900745biological_processpositive regulation of p38MAPK cascade
F1904047molecular_functionS-adenosyl-L-methionine binding
F1904263biological_processpositive regulation of TORC1 signaling
F1905168biological_processpositive regulation of double-strand break repair via homologous recombination
G0001701biological_processin utero embryonic development
G0003723molecular_functionRNA binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005737cellular_componentcytoplasm
G0005765cellular_componentlysosomal membrane
G0005829cellular_componentcytosol
G0006338biological_processchromatin remodeling
G0006355biological_processregulation of DNA-templated transcription
G0006479biological_processprotein methylation
G0006974biological_processDNA damage response
G0007166biological_processcell surface receptor signaling pathway
G0008168molecular_functionmethyltransferase activity
G0008170molecular_functionN-methyltransferase activity
G0008276molecular_functionprotein methyltransferase activity
G0008284biological_processpositive regulation of cell population proliferation
G0008327molecular_functionmethyl-CpG binding
G0008380biological_processRNA splicing
G0016274molecular_functionprotein-arginine N-methyltransferase activity
G0016740molecular_functiontransferase activity
G0018216biological_processpeptidyl-arginine methylation
G0019082biological_processviral protein processing
G0019899molecular_functionenzyme binding
G0030510biological_processregulation of BMP signaling pathway
G0031175biological_processneuron projection development
G0032259biological_processmethylation
G0034709cellular_componentmethylosome
G0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
G0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
G0042054molecular_functionhistone methyltransferase activity
G0042802molecular_functionidentical protein binding
G0043066biological_processnegative regulation of apoptotic process
G0044020molecular_functionhistone H4R3 methyltransferase activity
G0045648biological_processpositive regulation of erythrocyte differentiation
G0045652biological_processregulation of megakaryocyte differentiation
G0045653biological_processnegative regulation of megakaryocyte differentiation
G0045727biological_processpositive regulation of translation
G0046329biological_processnegative regulation of JNK cascade
G0046985biological_processpositive regulation of hemoglobin biosynthetic process
G0048273molecular_functionmitogen-activated protein kinase p38 binding
G0048738biological_processcardiac muscle tissue development
G0051260biological_processprotein homooligomerization
G0061431biological_processcellular response to methionine
G0106080molecular_functionGATOR1 complex binding
G0140939molecular_functionhistone H4 methyltransferase activity
G1900745biological_processpositive regulation of p38MAPK cascade
G1904047molecular_functionS-adenosyl-L-methionine binding
G1904263biological_processpositive regulation of TORC1 signaling
G1905168biological_processpositive regulation of double-strand break repair via homologous recombination
H0001701biological_processin utero embryonic development
H0003723molecular_functionRNA binding
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005737cellular_componentcytoplasm
H0005765cellular_componentlysosomal membrane
H0005829cellular_componentcytosol
H0006338biological_processchromatin remodeling
H0006355biological_processregulation of DNA-templated transcription
H0006479biological_processprotein methylation
H0006974biological_processDNA damage response
H0007166biological_processcell surface receptor signaling pathway
H0008168molecular_functionmethyltransferase activity
H0008170molecular_functionN-methyltransferase activity
H0008276molecular_functionprotein methyltransferase activity
H0008284biological_processpositive regulation of cell population proliferation
H0008327molecular_functionmethyl-CpG binding
H0008380biological_processRNA splicing
H0016274molecular_functionprotein-arginine N-methyltransferase activity
H0016740molecular_functiontransferase activity
H0018216biological_processpeptidyl-arginine methylation
H0019082biological_processviral protein processing
H0019899molecular_functionenzyme binding
H0030510biological_processregulation of BMP signaling pathway
H0031175biological_processneuron projection development
H0032259biological_processmethylation
H0034709cellular_componentmethylosome
H0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
H0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
H0042054molecular_functionhistone methyltransferase activity
H0042802molecular_functionidentical protein binding
H0043066biological_processnegative regulation of apoptotic process
H0044020molecular_functionhistone H4R3 methyltransferase activity
H0045648biological_processpositive regulation of erythrocyte differentiation
H0045652biological_processregulation of megakaryocyte differentiation
H0045653biological_processnegative regulation of megakaryocyte differentiation
H0045727biological_processpositive regulation of translation
H0046329biological_processnegative regulation of JNK cascade
H0046985biological_processpositive regulation of hemoglobin biosynthetic process
H0048273molecular_functionmitogen-activated protein kinase p38 binding
H0048738biological_processcardiac muscle tissue development
H0051260biological_processprotein homooligomerization
H0061431biological_processcellular response to methionine
H0106080molecular_functionGATOR1 complex binding
H0140939molecular_functionhistone H4 methyltransferase activity
H1900745biological_processpositive regulation of p38MAPK cascade
H1904047molecular_functionS-adenosyl-L-methionine binding
H1904263biological_processpositive regulation of TORC1 signaling
H1905168biological_processpositive regulation of double-strand break repair via homologous recombination
I0001701biological_processin utero embryonic development
I0003723molecular_functionRNA binding
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005737cellular_componentcytoplasm
I0005765cellular_componentlysosomal membrane
I0005829cellular_componentcytosol
I0006338biological_processchromatin remodeling
I0006355biological_processregulation of DNA-templated transcription
I0006479biological_processprotein methylation
I0006974biological_processDNA damage response
I0007166biological_processcell surface receptor signaling pathway
I0008168molecular_functionmethyltransferase activity
I0008170molecular_functionN-methyltransferase activity
I0008276molecular_functionprotein methyltransferase activity
I0008284biological_processpositive regulation of cell population proliferation
I0008327molecular_functionmethyl-CpG binding
I0008380biological_processRNA splicing
I0016274molecular_functionprotein-arginine N-methyltransferase activity
I0016740molecular_functiontransferase activity
I0018216biological_processpeptidyl-arginine methylation
I0019082biological_processviral protein processing
I0019899molecular_functionenzyme binding
I0030510biological_processregulation of BMP signaling pathway
I0031175biological_processneuron projection development
I0032259biological_processmethylation
I0034709cellular_componentmethylosome
I0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
I0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
I0042054molecular_functionhistone methyltransferase activity
I0042802molecular_functionidentical protein binding
I0043066biological_processnegative regulation of apoptotic process
I0044020molecular_functionhistone H4R3 methyltransferase activity
I0045648biological_processpositive regulation of erythrocyte differentiation
I0045652biological_processregulation of megakaryocyte differentiation
I0045653biological_processnegative regulation of megakaryocyte differentiation
I0045727biological_processpositive regulation of translation
I0046329biological_processnegative regulation of JNK cascade
I0046985biological_processpositive regulation of hemoglobin biosynthetic process
I0048273molecular_functionmitogen-activated protein kinase p38 binding
I0048738biological_processcardiac muscle tissue development
I0051260biological_processprotein homooligomerization
I0061431biological_processcellular response to methionine
I0106080molecular_functionGATOR1 complex binding
I0140939molecular_functionhistone H4 methyltransferase activity
I1900745biological_processpositive regulation of p38MAPK cascade
I1904047molecular_functionS-adenosyl-L-methionine binding
I1904263biological_processpositive regulation of TORC1 signaling
I1905168biological_processpositive regulation of double-strand break repair via homologous recombination
J0001701biological_processin utero embryonic development
J0003723molecular_functionRNA binding
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005737cellular_componentcytoplasm
J0005765cellular_componentlysosomal membrane
J0005829cellular_componentcytosol
J0006338biological_processchromatin remodeling
J0006355biological_processregulation of DNA-templated transcription
J0006479biological_processprotein methylation
J0006974biological_processDNA damage response
J0007166biological_processcell surface receptor signaling pathway
J0008168molecular_functionmethyltransferase activity
J0008170molecular_functionN-methyltransferase activity
J0008276molecular_functionprotein methyltransferase activity
J0008284biological_processpositive regulation of cell population proliferation
J0008327molecular_functionmethyl-CpG binding
J0008380biological_processRNA splicing
J0016274molecular_functionprotein-arginine N-methyltransferase activity
J0016740molecular_functiontransferase activity
J0018216biological_processpeptidyl-arginine methylation
J0019082biological_processviral protein processing
J0019899molecular_functionenzyme binding
J0030510biological_processregulation of BMP signaling pathway
J0031175biological_processneuron projection development
J0032259biological_processmethylation
J0034709cellular_componentmethylosome
J0035241molecular_functionprotein-arginine omega-N monomethyltransferase activity
J0035242molecular_functionprotein-arginine omega-N asymmetric methyltransferase activity
J0042054molecular_functionhistone methyltransferase activity
J0042802molecular_functionidentical protein binding
J0043066biological_processnegative regulation of apoptotic process
J0044020molecular_functionhistone H4R3 methyltransferase activity
J0045648biological_processpositive regulation of erythrocyte differentiation
J0045652biological_processregulation of megakaryocyte differentiation
J0045653biological_processnegative regulation of megakaryocyte differentiation
J0045727biological_processpositive regulation of translation
J0046329biological_processnegative regulation of JNK cascade
J0046985biological_processpositive regulation of hemoglobin biosynthetic process
J0048273molecular_functionmitogen-activated protein kinase p38 binding
J0048738biological_processcardiac muscle tissue development
J0051260biological_processprotein homooligomerization
J0061431biological_processcellular response to methionine
J0106080molecular_functionGATOR1 complex binding
J0140939molecular_functionhistone H4 methyltransferase activity
J1900745biological_processpositive regulation of p38MAPK cascade
J1904047molecular_functionS-adenosyl-L-methionine binding
J1904263biological_processpositive regulation of TORC1 signaling
J1905168biological_processpositive regulation of double-strand break repair via homologous recombination
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsActive site: {"evidences":[{"source":"UniProtKB","id":"Q63009","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues50
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"Q63009","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues10
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"31257072","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6NT2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues10
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q9JIF0","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues20
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9JIF0","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues20
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues20
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"Q9JIF0","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

243531

PDB entries from 2025-10-22

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