9JK7

Human VANGL2 hexamer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001725	cellular_component	stress fiber
A	0001736	biological_process	establishment of planar polarity
A	0001843	biological_process	neural tube closure
A	0001947	biological_process	heart looping
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0005911	cellular_component	cell-cell junction
A	0007275	biological_process	multicellular organism development
A	0016020	cellular_component	membrane
A	0016323	cellular_component	basolateral plasma membrane
A	0016324	cellular_component	apical plasma membrane
A	0016328	cellular_component	lateral plasma membrane
A	0030134	cellular_component	COPII-coated ER to Golgi transport vesicle
A	0035787	biological_process	cell migration involved in kidney development
A	0036514	biological_process	dopaminergic neuron axon guidance
A	0036515	biological_process	serotonergic neuron axon guidance
A	0045176	biological_process	apical protein localization
A	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
A	0060187	cellular_component	cell pole
A	0071944	cellular_component	cell periphery
A	0090651	cellular_component	apical cytoplasm
A	0098839	cellular_component	postsynaptic density membrane
A	0098978	cellular_component	glutamatergic synapse
A	1905515	biological_process	non-motile cilium assembly
A	1905806	biological_process	regulation of synapse pruning
B	0001725	cellular_component	stress fiber
B	0001736	biological_process	establishment of planar polarity
B	0001843	biological_process	neural tube closure
B	0001947	biological_process	heart looping
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0005911	cellular_component	cell-cell junction
B	0007275	biological_process	multicellular organism development
B	0016020	cellular_component	membrane
B	0016323	cellular_component	basolateral plasma membrane
B	0016324	cellular_component	apical plasma membrane
B	0016328	cellular_component	lateral plasma membrane
B	0030134	cellular_component	COPII-coated ER to Golgi transport vesicle
B	0035787	biological_process	cell migration involved in kidney development
B	0036514	biological_process	dopaminergic neuron axon guidance
B	0036515	biological_process	serotonergic neuron axon guidance
B	0045176	biological_process	apical protein localization
B	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
B	0060187	cellular_component	cell pole
B	0071944	cellular_component	cell periphery
B	0090651	cellular_component	apical cytoplasm
B	0098839	cellular_component	postsynaptic density membrane
B	0098978	cellular_component	glutamatergic synapse
B	1905515	biological_process	non-motile cilium assembly
B	1905806	biological_process	regulation of synapse pruning
C	0001725	cellular_component	stress fiber
C	0001736	biological_process	establishment of planar polarity
C	0001843	biological_process	neural tube closure
C	0001947	biological_process	heart looping
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0005911	cellular_component	cell-cell junction
C	0007275	biological_process	multicellular organism development
C	0016020	cellular_component	membrane
C	0016323	cellular_component	basolateral plasma membrane
C	0016324	cellular_component	apical plasma membrane
C	0016328	cellular_component	lateral plasma membrane
C	0030134	cellular_component	COPII-coated ER to Golgi transport vesicle
C	0035787	biological_process	cell migration involved in kidney development
C	0036514	biological_process	dopaminergic neuron axon guidance
C	0036515	biological_process	serotonergic neuron axon guidance
C	0045176	biological_process	apical protein localization
C	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
C	0060187	cellular_component	cell pole
C	0071944	cellular_component	cell periphery
C	0090651	cellular_component	apical cytoplasm
C	0098839	cellular_component	postsynaptic density membrane
C	0098978	cellular_component	glutamatergic synapse
C	1905515	biological_process	non-motile cilium assembly
C	1905806	biological_process	regulation of synapse pruning
D	0001725	cellular_component	stress fiber
D	0001736	biological_process	establishment of planar polarity
D	0001843	biological_process	neural tube closure
D	0001947	biological_process	heart looping
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0005911	cellular_component	cell-cell junction
D	0007275	biological_process	multicellular organism development
D	0016020	cellular_component	membrane
D	0016323	cellular_component	basolateral plasma membrane
D	0016324	cellular_component	apical plasma membrane
D	0016328	cellular_component	lateral plasma membrane
D	0030134	cellular_component	COPII-coated ER to Golgi transport vesicle
D	0035787	biological_process	cell migration involved in kidney development
D	0036514	biological_process	dopaminergic neuron axon guidance
D	0036515	biological_process	serotonergic neuron axon guidance
D	0045176	biological_process	apical protein localization
D	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
D	0060187	cellular_component	cell pole
D	0071944	cellular_component	cell periphery
D	0090651	cellular_component	apical cytoplasm
D	0098839	cellular_component	postsynaptic density membrane
D	0098978	cellular_component	glutamatergic synapse
D	1905515	biological_process	non-motile cilium assembly
D	1905806	biological_process	regulation of synapse pruning
E	0001725	cellular_component	stress fiber
E	0001736	biological_process	establishment of planar polarity
E	0001843	biological_process	neural tube closure
E	0001947	biological_process	heart looping
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0005911	cellular_component	cell-cell junction
E	0007275	biological_process	multicellular organism development
E	0016020	cellular_component	membrane
E	0016323	cellular_component	basolateral plasma membrane
E	0016324	cellular_component	apical plasma membrane
E	0016328	cellular_component	lateral plasma membrane
E	0030134	cellular_component	COPII-coated ER to Golgi transport vesicle
E	0035787	biological_process	cell migration involved in kidney development
E	0036514	biological_process	dopaminergic neuron axon guidance
E	0036515	biological_process	serotonergic neuron axon guidance
E	0045176	biological_process	apical protein localization
E	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
E	0060187	cellular_component	cell pole
E	0071944	cellular_component	cell periphery
E	0090651	cellular_component	apical cytoplasm
E	0098839	cellular_component	postsynaptic density membrane
E	0098978	cellular_component	glutamatergic synapse
E	1905515	biological_process	non-motile cilium assembly
E	1905806	biological_process	regulation of synapse pruning
F	0001725	cellular_component	stress fiber
F	0001736	biological_process	establishment of planar polarity
F	0001843	biological_process	neural tube closure
F	0001947	biological_process	heart looping
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0005911	cellular_component	cell-cell junction
F	0007275	biological_process	multicellular organism development
F	0016020	cellular_component	membrane
F	0016323	cellular_component	basolateral plasma membrane
F	0016324	cellular_component	apical plasma membrane
F	0016328	cellular_component	lateral plasma membrane
F	0030134	cellular_component	COPII-coated ER to Golgi transport vesicle
F	0035787	biological_process	cell migration involved in kidney development
F	0036514	biological_process	dopaminergic neuron axon guidance
F	0036515	biological_process	serotonergic neuron axon guidance
F	0045176	biological_process	apical protein localization
F	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
F	0060187	cellular_component	cell pole
F	0071944	cellular_component	cell periphery
F	0090651	cellular_component	apical cytoplasm
F	0098839	cellular_component	postsynaptic density membrane
F	0098978	cellular_component	glutamatergic synapse
F	1905515	biological_process	non-motile cilium assembly
F	1905806	biological_process	regulation of synapse pruning

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	204
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	54
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	120
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---