9J8P

Cryo-EM structure of human TUT1 complexed with U6 snRNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0003730	molecular_function	mRNA 3'-UTR binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005847	cellular_component	mRNA cleavage and polyadenylation specificity factor complex
A	0006397	biological_process	mRNA processing
A	0008270	molecular_function	zinc ion binding
A	0016180	biological_process	snRNA processing
A	0016607	cellular_component	nuclear speck
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0017070	molecular_function	U6 snRNA binding
A	0019899	molecular_function	enzyme binding
A	0031123	biological_process	RNA 3'-end processing
A	0031124	biological_process	mRNA 3'-end processing
A	0034477	biological_process	U6 snRNA 3'-end processing
A	0046872	molecular_function	metal ion binding
A	0050265	molecular_function	RNA uridylyltransferase activity
A	0051252	biological_process	regulation of RNA metabolic process
A	0071044	biological_process	histone mRNA catabolic process
A	0140767	molecular_function	enzyme-substrate adaptor activity
A	0180010	biological_process	co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway
A	1990817	molecular_function	poly(A) RNA polymerase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	72
Details	Domain: {"description":"RRM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	58
Details	Domain: {"description":"PAP-associated","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

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site_id	SWS_FT_FI3
Number of Residues	30
Details	Zinc finger: {"description":"Matrin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00130","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28589955","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5WU4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28589955","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5WU2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WU3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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