9J8N

Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (Low mobility complex)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000786	cellular_component	nucleosome
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0006325	biological_process	chromatin organization
A	0006334	biological_process	nucleosome assembly
A	0010467	biological_process	gene expression
A	0016020	cellular_component	membrane
A	0032200	biological_process	telomere organization
A	0032991	cellular_component	protein-containing complex
A	0040029	biological_process	epigenetic regulation of gene expression
A	0045296	molecular_function	cadherin binding
A	0070062	cellular_component	extracellular exosome
B	0000781	cellular_component	chromosome, telomeric region
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0006325	biological_process	chromatin organization
B	0006334	biological_process	nucleosome assembly
B	0016020	cellular_component	membrane
B	0030527	molecular_function	structural constituent of chromatin
B	0032200	biological_process	telomere organization
B	0032991	cellular_component	protein-containing complex
B	0043505	cellular_component	CENP-A containing nucleosome
B	0045653	biological_process	negative regulation of megakaryocyte differentiation
B	0061644	biological_process	protein localization to CENP-A containing chromatin
B	0070062	cellular_component	extracellular exosome
C	0000786	cellular_component	nucleosome
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0006325	biological_process	chromatin organization
C	0008285	biological_process	negative regulation of cell population proliferation
C	0030527	molecular_function	structural constituent of chromatin
C	0031507	biological_process	heterochromatin formation
C	0043505	cellular_component	CENP-A containing nucleosome
C	0061644	biological_process	protein localization to CENP-A containing chromatin
C	0070062	cellular_component	extracellular exosome
D	0000786	cellular_component	nucleosome
D	0001530	molecular_function	lipopolysaccharide binding
D	0002227	biological_process	innate immune response in mucosa
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005615	cellular_component	extracellular space
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005694	cellular_component	chromosome
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006325	biological_process	chromatin organization
D	0006334	biological_process	nucleosome assembly
D	0010804	biological_process	negative regulation of tumor necrosis factor-mediated signaling pathway
D	0019731	biological_process	antibacterial humoral response
D	0031640	biological_process	killing of cells of another organism
D	0042742	biological_process	defense response to bacterium
D	0043505	cellular_component	CENP-A containing nucleosome
D	0050829	biological_process	defense response to Gram-negative bacterium
D	0050830	biological_process	defense response to Gram-positive bacterium
D	0061644	biological_process	protein localization to CENP-A containing chromatin
D	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
E	0000786	cellular_component	nucleosome
E	0003677	molecular_function	DNA binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005694	cellular_component	chromosome
E	0006325	biological_process	chromatin organization
E	0006334	biological_process	nucleosome assembly
E	0010467	biological_process	gene expression
E	0016020	cellular_component	membrane
E	0032200	biological_process	telomere organization
E	0032991	cellular_component	protein-containing complex
E	0040029	biological_process	epigenetic regulation of gene expression
E	0045296	molecular_function	cadherin binding
E	0070062	cellular_component	extracellular exosome
F	0000781	cellular_component	chromosome, telomeric region
F	0000786	cellular_component	nucleosome
F	0003677	molecular_function	DNA binding
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005694	cellular_component	chromosome
F	0006325	biological_process	chromatin organization
F	0006334	biological_process	nucleosome assembly
F	0016020	cellular_component	membrane
F	0030527	molecular_function	structural constituent of chromatin
F	0032200	biological_process	telomere organization
F	0032991	cellular_component	protein-containing complex
F	0043505	cellular_component	CENP-A containing nucleosome
F	0045653	biological_process	negative regulation of megakaryocyte differentiation
F	0061644	biological_process	protein localization to CENP-A containing chromatin
F	0070062	cellular_component	extracellular exosome
G	0000786	cellular_component	nucleosome
G	0003677	molecular_function	DNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005694	cellular_component	chromosome
G	0006325	biological_process	chromatin organization
G	0008285	biological_process	negative regulation of cell population proliferation
G	0030527	molecular_function	structural constituent of chromatin
G	0031507	biological_process	heterochromatin formation
G	0043505	cellular_component	CENP-A containing nucleosome
G	0061644	biological_process	protein localization to CENP-A containing chromatin
G	0070062	cellular_component	extracellular exosome
H	0000786	cellular_component	nucleosome
H	0001530	molecular_function	lipopolysaccharide binding
H	0002227	biological_process	innate immune response in mucosa
H	0003677	molecular_function	DNA binding
H	0005515	molecular_function	protein binding
H	0005615	cellular_component	extracellular space
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005694	cellular_component	chromosome
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006325	biological_process	chromatin organization
H	0006334	biological_process	nucleosome assembly
H	0010804	biological_process	negative regulation of tumor necrosis factor-mediated signaling pathway
H	0019731	biological_process	antibacterial humoral response
H	0031640	biological_process	killing of cells of another organism
H	0042742	biological_process	defense response to bacterium
H	0043505	cellular_component	CENP-A containing nucleosome
H	0050829	biological_process	defense response to Gram-negative bacterium
H	0050830	biological_process	defense response to Gram-positive bacterium
H	0061644	biological_process	protein localization to CENP-A containing chromatin
H	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
K	0000785	cellular_component	chromatin
K	0000793	cellular_component	condensed chromosome
K	0003677	molecular_function	DNA binding
K	0003690	molecular_function	double-stranded DNA binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005635	cellular_component	nuclear envelope
K	0005654	cellular_component	nucleoplasm
K	0005694	cellular_component	chromosome
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006281	biological_process	DNA repair
K	0006325	biological_process	chromatin organization
K	0006979	biological_process	response to oxidative stress
K	0007084	biological_process	mitotic nuclear membrane reassembly
K	0009615	biological_process	response to virus
K	0010836	biological_process	negative regulation of protein ADP-ribosylation
K	0015074	biological_process	DNA integration
K	0032480	biological_process	negative regulation of type I interferon production
K	0032481	biological_process	positive regulation of type I interferon production
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0045071	biological_process	negative regulation of viral genome replication
K	0045824	biological_process	negative regulation of innate immune response
K	0051276	biological_process	chromosome organization
K	0140896	biological_process	cGAS/STING signaling pathway
K	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
L	0000785	cellular_component	chromatin
L	0000793	cellular_component	condensed chromosome
L	0003677	molecular_function	DNA binding
L	0003690	molecular_function	double-stranded DNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005635	cellular_component	nuclear envelope
L	0005654	cellular_component	nucleoplasm
L	0005694	cellular_component	chromosome
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006281	biological_process	DNA repair
L	0006325	biological_process	chromatin organization
L	0006979	biological_process	response to oxidative stress
L	0007084	biological_process	mitotic nuclear membrane reassembly
L	0009615	biological_process	response to virus
L	0010836	biological_process	negative regulation of protein ADP-ribosylation
L	0015074	biological_process	DNA integration
L	0032480	biological_process	negative regulation of type I interferon production
L	0032481	biological_process	positive regulation of type I interferon production
L	0042802	molecular_function	identical protein binding
L	0042803	molecular_function	protein homodimerization activity
L	0045071	biological_process	negative regulation of viral genome replication
L	0045824	biological_process	negative regulation of innate immune response
L	0051276	biological_process	chromosome organization
L	0140896	biological_process	cGAS/STING signaling pathway
L	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
N	0000785	cellular_component	chromatin
N	0000793	cellular_component	condensed chromosome
N	0003677	molecular_function	DNA binding
N	0003690	molecular_function	double-stranded DNA binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005635	cellular_component	nuclear envelope
N	0005654	cellular_component	nucleoplasm
N	0005694	cellular_component	chromosome
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006281	biological_process	DNA repair
N	0006325	biological_process	chromatin organization
N	0006979	biological_process	response to oxidative stress
N	0007084	biological_process	mitotic nuclear membrane reassembly
N	0009615	biological_process	response to virus
N	0010836	biological_process	negative regulation of protein ADP-ribosylation
N	0015074	biological_process	DNA integration
N	0032480	biological_process	negative regulation of type I interferon production
N	0032481	biological_process	positive regulation of type I interferon production
N	0042802	molecular_function	identical protein binding
N	0042803	molecular_function	protein homodimerization activity
N	0045071	biological_process	negative regulation of viral genome replication
N	0045824	biological_process	negative regulation of innate immune response
N	0051276	biological_process	chromosome organization
N	0140896	biological_process	cGAS/STING signaling pathway
N	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
O	0000785	cellular_component	chromatin
O	0000793	cellular_component	condensed chromosome
O	0003677	molecular_function	DNA binding
O	0003690	molecular_function	double-stranded DNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005635	cellular_component	nuclear envelope
O	0005654	cellular_component	nucleoplasm
O	0005694	cellular_component	chromosome
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006281	biological_process	DNA repair
O	0006325	biological_process	chromatin organization
O	0006979	biological_process	response to oxidative stress
O	0007084	biological_process	mitotic nuclear membrane reassembly
O	0009615	biological_process	response to virus
O	0010836	biological_process	negative regulation of protein ADP-ribosylation
O	0015074	biological_process	DNA integration
O	0032480	biological_process	negative regulation of type I interferon production
O	0032481	biological_process	positive regulation of type I interferon production
O	0042802	molecular_function	identical protein binding
O	0042803	molecular_function	protein homodimerization activity
O	0045071	biological_process	negative regulation of viral genome replication
O	0045824	biological_process	negative regulation of innate immune response
O	0051276	biological_process	chromosome organization
O	0140896	biological_process	cGAS/STING signaling pathway
O	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
a	0000786	cellular_component	nucleosome
a	0003677	molecular_function	DNA binding
a	0005515	molecular_function	protein binding
a	0005576	cellular_component	extracellular region
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005694	cellular_component	chromosome
a	0006325	biological_process	chromatin organization
a	0006334	biological_process	nucleosome assembly
a	0010467	biological_process	gene expression
a	0016020	cellular_component	membrane
a	0032200	biological_process	telomere organization
a	0032991	cellular_component	protein-containing complex
a	0040029	biological_process	epigenetic regulation of gene expression
a	0045296	molecular_function	cadherin binding
a	0070062	cellular_component	extracellular exosome
b	0000781	cellular_component	chromosome, telomeric region
b	0000786	cellular_component	nucleosome
b	0003677	molecular_function	DNA binding
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005576	cellular_component	extracellular region
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005694	cellular_component	chromosome
b	0006325	biological_process	chromatin organization
b	0006334	biological_process	nucleosome assembly
b	0016020	cellular_component	membrane
b	0030527	molecular_function	structural constituent of chromatin
b	0032200	biological_process	telomere organization
b	0032991	cellular_component	protein-containing complex
b	0043505	cellular_component	CENP-A containing nucleosome
b	0045653	biological_process	negative regulation of megakaryocyte differentiation
b	0061644	biological_process	protein localization to CENP-A containing chromatin
b	0070062	cellular_component	extracellular exosome
c	0000786	cellular_component	nucleosome
c	0003677	molecular_function	DNA binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005694	cellular_component	chromosome
c	0006325	biological_process	chromatin organization
c	0008285	biological_process	negative regulation of cell population proliferation
c	0030527	molecular_function	structural constituent of chromatin
c	0031507	biological_process	heterochromatin formation
c	0043505	cellular_component	CENP-A containing nucleosome
c	0061644	biological_process	protein localization to CENP-A containing chromatin
c	0070062	cellular_component	extracellular exosome
d	0000786	cellular_component	nucleosome
d	0001530	molecular_function	lipopolysaccharide binding
d	0002227	biological_process	innate immune response in mucosa
d	0003677	molecular_function	DNA binding
d	0005515	molecular_function	protein binding
d	0005615	cellular_component	extracellular space
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005694	cellular_component	chromosome
d	0005829	cellular_component	cytosol
d	0005886	cellular_component	plasma membrane
d	0006325	biological_process	chromatin organization
d	0006334	biological_process	nucleosome assembly
d	0010804	biological_process	negative regulation of tumor necrosis factor-mediated signaling pathway
d	0019731	biological_process	antibacterial humoral response
d	0031640	biological_process	killing of cells of another organism
d	0042742	biological_process	defense response to bacterium
d	0043505	cellular_component	CENP-A containing nucleosome
d	0050829	biological_process	defense response to Gram-negative bacterium
d	0050830	biological_process	defense response to Gram-positive bacterium
d	0061644	biological_process	protein localization to CENP-A containing chromatin
d	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
e	0000786	cellular_component	nucleosome
e	0003677	molecular_function	DNA binding
e	0005515	molecular_function	protein binding
e	0005576	cellular_component	extracellular region
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005694	cellular_component	chromosome
e	0006325	biological_process	chromatin organization
e	0006334	biological_process	nucleosome assembly
e	0010467	biological_process	gene expression
e	0016020	cellular_component	membrane
e	0032200	biological_process	telomere organization
e	0032991	cellular_component	protein-containing complex
e	0040029	biological_process	epigenetic regulation of gene expression
e	0045296	molecular_function	cadherin binding
e	0070062	cellular_component	extracellular exosome
f	0000781	cellular_component	chromosome, telomeric region
f	0000786	cellular_component	nucleosome
f	0003677	molecular_function	DNA binding
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005576	cellular_component	extracellular region
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005694	cellular_component	chromosome
f	0006325	biological_process	chromatin organization
f	0006334	biological_process	nucleosome assembly
f	0016020	cellular_component	membrane
f	0030527	molecular_function	structural constituent of chromatin
f	0032200	biological_process	telomere organization
f	0032991	cellular_component	protein-containing complex
f	0043505	cellular_component	CENP-A containing nucleosome
f	0045653	biological_process	negative regulation of megakaryocyte differentiation
f	0061644	biological_process	protein localization to CENP-A containing chromatin
f	0070062	cellular_component	extracellular exosome
g	0000786	cellular_component	nucleosome
g	0003677	molecular_function	DNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005694	cellular_component	chromosome
g	0006325	biological_process	chromatin organization
g	0008285	biological_process	negative regulation of cell population proliferation
g	0030527	molecular_function	structural constituent of chromatin
g	0031507	biological_process	heterochromatin formation
g	0043505	cellular_component	CENP-A containing nucleosome
g	0061644	biological_process	protein localization to CENP-A containing chromatin
g	0070062	cellular_component	extracellular exosome
h	0000786	cellular_component	nucleosome
h	0001530	molecular_function	lipopolysaccharide binding
h	0002227	biological_process	innate immune response in mucosa
h	0003677	molecular_function	DNA binding
h	0005515	molecular_function	protein binding
h	0005615	cellular_component	extracellular space
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005694	cellular_component	chromosome
h	0005829	cellular_component	cytosol
h	0005886	cellular_component	plasma membrane
h	0006325	biological_process	chromatin organization
h	0006334	biological_process	nucleosome assembly
h	0010804	biological_process	negative regulation of tumor necrosis factor-mediated signaling pathway
h	0019731	biological_process	antibacterial humoral response
h	0031640	biological_process	killing of cells of another organism
h	0042742	biological_process	defense response to bacterium
h	0043505	cellular_component	CENP-A containing nucleosome
h	0050829	biological_process	defense response to Gram-negative bacterium
h	0050830	biological_process	defense response to Gram-positive bacterium
h	0061644	biological_process	protein localization to CENP-A containing chromatin
h	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
k	0000785	cellular_component	chromatin
k	0000793	cellular_component	condensed chromosome
k	0003677	molecular_function	DNA binding
k	0003690	molecular_function	double-stranded DNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005635	cellular_component	nuclear envelope
k	0005654	cellular_component	nucleoplasm
k	0005694	cellular_component	chromosome
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0006281	biological_process	DNA repair
k	0006325	biological_process	chromatin organization
k	0006979	biological_process	response to oxidative stress
k	0007084	biological_process	mitotic nuclear membrane reassembly
k	0009615	biological_process	response to virus
k	0010836	biological_process	negative regulation of protein ADP-ribosylation
k	0015074	biological_process	DNA integration
k	0032480	biological_process	negative regulation of type I interferon production
k	0032481	biological_process	positive regulation of type I interferon production
k	0042802	molecular_function	identical protein binding
k	0042803	molecular_function	protein homodimerization activity
k	0045071	biological_process	negative regulation of viral genome replication
k	0045824	biological_process	negative regulation of innate immune response
k	0051276	biological_process	chromosome organization
k	0140896	biological_process	cGAS/STING signaling pathway
k	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
l	0000785	cellular_component	chromatin
l	0000793	cellular_component	condensed chromosome
l	0003677	molecular_function	DNA binding
l	0003690	molecular_function	double-stranded DNA binding
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005635	cellular_component	nuclear envelope
l	0005654	cellular_component	nucleoplasm
l	0005694	cellular_component	chromosome
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006281	biological_process	DNA repair
l	0006325	biological_process	chromatin organization
l	0006979	biological_process	response to oxidative stress
l	0007084	biological_process	mitotic nuclear membrane reassembly
l	0009615	biological_process	response to virus
l	0010836	biological_process	negative regulation of protein ADP-ribosylation
l	0015074	biological_process	DNA integration
l	0032480	biological_process	negative regulation of type I interferon production
l	0032481	biological_process	positive regulation of type I interferon production
l	0042802	molecular_function	identical protein binding
l	0042803	molecular_function	protein homodimerization activity
l	0045071	biological_process	negative regulation of viral genome replication
l	0045824	biological_process	negative regulation of innate immune response
l	0051276	biological_process	chromosome organization
l	0140896	biological_process	cGAS/STING signaling pathway
l	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
n	0000785	cellular_component	chromatin
n	0000793	cellular_component	condensed chromosome
n	0003677	molecular_function	DNA binding
n	0003690	molecular_function	double-stranded DNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005635	cellular_component	nuclear envelope
n	0005654	cellular_component	nucleoplasm
n	0005694	cellular_component	chromosome
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006281	biological_process	DNA repair
n	0006325	biological_process	chromatin organization
n	0006979	biological_process	response to oxidative stress
n	0007084	biological_process	mitotic nuclear membrane reassembly
n	0009615	biological_process	response to virus
n	0010836	biological_process	negative regulation of protein ADP-ribosylation
n	0015074	biological_process	DNA integration
n	0032480	biological_process	negative regulation of type I interferon production
n	0032481	biological_process	positive regulation of type I interferon production
n	0042802	molecular_function	identical protein binding
n	0042803	molecular_function	protein homodimerization activity
n	0045071	biological_process	negative regulation of viral genome replication
n	0045824	biological_process	negative regulation of innate immune response
n	0051276	biological_process	chromosome organization
n	0140896	biological_process	cGAS/STING signaling pathway
n	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
o	0000785	cellular_component	chromatin
o	0000793	cellular_component	condensed chromosome
o	0003677	molecular_function	DNA binding
o	0003690	molecular_function	double-stranded DNA binding
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005635	cellular_component	nuclear envelope
o	0005654	cellular_component	nucleoplasm
o	0005694	cellular_component	chromosome
o	0005737	cellular_component	cytoplasm
o	0005829	cellular_component	cytosol
o	0006281	biological_process	DNA repair
o	0006325	biological_process	chromatin organization
o	0006979	biological_process	response to oxidative stress
o	0007084	biological_process	mitotic nuclear membrane reassembly
o	0009615	biological_process	response to virus
o	0010836	biological_process	negative regulation of protein ADP-ribosylation
o	0015074	biological_process	DNA integration
o	0032480	biological_process	negative regulation of type I interferon production
o	0032481	biological_process	positive regulation of type I interferon production
o	0042802	molecular_function	identical protein binding
o	0042803	molecular_function	protein homodimerization activity
o	0045071	biological_process	negative regulation of viral genome replication
o	0045824	biological_process	negative regulation of innate immune response
o	0051276	biological_process	chromosome organization
o	0140896	biological_process	cGAS/STING signaling pathway
o	0160049	biological_process	negative regulation of cGAS/STING signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
C	ALA21-VAL27

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site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
B	GLY14-HIS18

---

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
A	LYS14-LEU20

---

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
D	ARG92-GLY114

---

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI

Chain	Residue	Details
A	PRO66-ILE74

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
M	SER414
P	SER414
m	SER414
p	SER414
k	MET1
l	MET1
n	MET1
o	MET1

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:24741066

Chain	Residue	Details
M	THR416
k	THR3
l	THR2
l	THR3
n	THR2
n	THR3
o	THR2
o	THR3
P	THR416
m	THR416
p	THR416
N	THR2
N	THR3
O	THR2
O	THR3
k	THR2

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P48678

Chain	Residue	Details
M	LYS417
p	LYS417
p	LYS457
p	LYS486
H	LYS20
H	LYS23
H	LYS43
H	LYS85
d	LYS5
d	LYS11
d	LYS15
M	LYS457
d	LYS16
d	LYS20
d	LYS23
d	LYS43
d	LYS85
h	LYS5
h	LYS11
h	LYS15
h	LYS16
h	LYS20
M	LYS486
h	LYS23
h	LYS43
h	LYS85
P	LYS417
P	LYS457
P	LYS486
m	LYS417
m	LYS457
m	LYS486

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:24741066

Chain	Residue	Details
M	SER423
M	SER426
P	SER423
P	SER426
m	SER423
m	SER426
p	SER423
p	SER426

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
M	SER429
f	LYS8
f	LYS16
f	LYS44
M	SER533
P	SER429
P	SER533
m	SER429
m	SER533
p	SER429
p	SER533
b	LYS44

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
M	SER431
b	LYS31
b	LYS77
b	LYS91
f	LYS12
f	LYS31
f	LYS77
f	LYS91
P	SER431
m	SER431
p	SER431
F	LYS12
F	LYS31
F	LYS77
F	LYS91
b	LYS12

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
M	LYS450
P	LYS450
m	LYS450
p	LYS450
c	LYS74
c	LYS75
g	LYS74
g	LYS75

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:24741066, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
M	SER458
h	LYS34
h	LYS116
h	LYS120
P	SER458
m	SER458
p	SER458
H	LYS116
H	LYS120
d	LYS34
d	LYS116
d	LYS120

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
M	SER463
g	LYS118
g	LYS119
g	LYS125
P	SER463
m	SER463
p	SER463
G	LYS119
G	LYS125
c	LYS118
c	LYS119
c	LYS125

---

site_id	SWS_FT_FI10
Number of Residues	8
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P48679

Chain	Residue	Details
M	THR496
M	THR510
P	THR496
P	THR510
m	THR496
m	THR510
p	THR496
p	THR510

---

site_id	SWS_FT_FI11
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
M	THR505
P	THR505
m	THR505
p	THR505
d	LYS46
d	LYS108
h	LYS46
h	LYS108

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P48678

Chain	Residue	Details
M	SER546
P	SER546
m	SER546
p	SER546
a	LYS18
c	LYS119
e	LYS18
g	LYS119

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P48678

Chain	Residue	Details
M	THR548
P	THR548
m	THR548
p	THR548

---

site_id	SWS_FT_FI14
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
M	LYS417
P	LYS417
m	LYS417
p	LYS417
d	ARG86
d	ARG92
h	ARG86
h	ARG92

---

site_id	SWS_FT_FI15
Number of Residues	12
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
D	THR115
p	LYS470
p	LYS486
M	LYS470
M	LYS486
h	THR115
P	LYS470
P	LYS486
m	LYS470
m	LYS486

---

site_id	SWS_FT_FI16
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733

Chain	Residue	Details
M	LYS420
f	LYS20
f	LYS59
f	LYS79
P	LYS420
m	LYS420
p	LYS420
F	LYS59
F	LYS79
b	LYS20
b	LYS59
b	LYS79

---

site_id	SWS_FT_FI17
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
M	LYS450
P	LYS450
m	LYS450
p	LYS450

---

site_id	SWS_FT_FI18
Number of Residues	8
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:16713563

Chain	Residue	Details
A	LYS37
D	LYS120
a	LYS37
H	LYS120
d	LYS120
h	LYS120

---

site_id	SWS_FT_FI19
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:Q5QNW6

Chain	Residue	Details
D	LYS20
H	LYS20
d	LYS20
h	LYS20

---

site_id	SWS_FT_FI20
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:21726816

Chain	Residue	Details
D	LYS34
H	LYS34
d	LYS34
h	LYS34

---

site_id	SWS_FT_FI21
Number of Residues	4
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435, ECO:0000269|PubMed:29211711

Chain	Residue	Details
A	LYS79
E	LYS79
a	LYS79
e	LYS79

---

site_id	SWS_FT_FI22
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:20850016

Chain	Residue	Details
A	THR80
E	THR80
a	THR80
e	THR80

---

site_id	SWS_FT_FI23
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P84243

Chain	Residue	Details
A	SER86
E	SER86
a	SER86
e	SER86

---

site_id	SWS_FT_FI24
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
A	THR107
E	THR107
a	THR107
e	THR107

---

site_id	SWS_FT_FI25
Number of Residues	4
Details	MOD_RES: N6-glutaryllysine; alternate => ECO:0000269|PubMed:31542297

Chain	Residue	Details
A	LYS115
E	LYS115
a	LYS115
e	LYS115

---

site_id	SWS_FT_FI26
Number of Residues	4
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435, ECO:0000269|PubMed:27436229

Chain	Residue	Details
A	LYS122
E	LYS122
a	LYS122
e	LYS122

---

site_id	SWS_FT_FI27
Number of Residues	4
Details	LIPID: N6-decanoyllysine => ECO:0000269|PubMed:35939806

Chain	Residue	Details
A	LYS18
E	LYS18
a	LYS18
e	LYS18

---