9J7A

local refinement of FEM1B bound with TOM20 (dimer)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000151	cellular_component	ubiquitin ligase complex
A	0002070	biological_process	epithelial cell maturation
A	0005123	molecular_function	death receptor binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006915	biological_process	apoptotic process
A	0016567	biological_process	protein ubiquitination
A	0031462	cellular_component	Cul2-RING ubiquitin ligase complex
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0046872	molecular_function	metal ion binding
A	0051438	biological_process	regulation of ubiquitin-protein transferase activity
A	0060442	biological_process	branching involved in prostate gland morphogenesis
A	0060743	biological_process	epithelial cell maturation involved in prostate gland development
A	0140627	biological_process	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
A	1902041	biological_process	regulation of extrinsic apoptotic signaling pathway via death domain receptors
A	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
A	2000001	biological_process	regulation of DNA damage checkpoint
D	0000151	cellular_component	ubiquitin ligase complex
D	0002070	biological_process	epithelial cell maturation
D	0005123	molecular_function	death receptor binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0006915	biological_process	apoptotic process
D	0016567	biological_process	protein ubiquitination
D	0031462	cellular_component	Cul2-RING ubiquitin ligase complex
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0046872	molecular_function	metal ion binding
D	0051438	biological_process	regulation of ubiquitin-protein transferase activity
D	0060442	biological_process	branching involved in prostate gland morphogenesis
D	0060743	biological_process	epithelial cell maturation involved in prostate gland development
D	0140627	biological_process	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
D	1902041	biological_process	regulation of extrinsic apoptotic signaling pathway via death domain receptors
D	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
D	2000001	biological_process	regulation of DNA damage checkpoint

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	58
Details	Repeat: {"description":"ANK 1"}

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Residue

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site_id	SWS_FT_FI2
Number of Residues	58
Details	Repeat: {"description":"ANK 2"}

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site_id	SWS_FT_FI3
Number of Residues	58
Details	Repeat: {"description":"ANK 3"}

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site_id	SWS_FT_FI4
Number of Residues	58
Details	Repeat: {"description":"ANK 4"}

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site_id	SWS_FT_FI5
Number of Residues	58
Details	Repeat: {"description":"ANK 5"}

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Residue

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site_id	SWS_FT_FI6
Number of Residues	60
Details	Repeat: {"description":"ANK 6"}

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Residue

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site_id	SWS_FT_FI7
Number of Residues	66
Details	Repeat: {"description":"TPR"}

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Residue

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site_id	SWS_FT_FI8
Number of Residues	88
Details	Repeat: {"description":"ANK 7"}

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Residue

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site_id	SWS_FT_FI9
Number of Residues	74
Details	Repeat: {"description":"ANK 8"}

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Residue

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site_id	SWS_FT_FI10
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9Z2G0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

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site_id	SWS_FT_FI11
Number of Residues	2
Details	Site: {"description":"Cleavage; by a caspase-3-like protease","evidences":[{"source":"PubMed","id":"10542291","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI12
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"24896179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25621951","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI13
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"24896179","evidenceCode":"ECO:0000269"}]}

Chain

Residue

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