9J2N
Cryo-EM structure of the human glucose transporter, GLUT7 in outward-facing open conformation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005353 | molecular_function | fructose transmembrane transporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008645 | biological_process | hexose transmembrane transport |
| A | 0015755 | biological_process | fructose transmembrane transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016324 | cellular_component | apical plasma membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0046323 | biological_process | D-glucose import |
| A | 0051119 | molecular_function | sugar transmembrane transporter activity |
| A | 0055056 | molecular_function | D-glucose transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0070837 | biological_process | dehydroascorbic acid transport |
| A | 1904659 | biological_process | D-glucose transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00216 |
| Number of Residues | 17 |
| Details | SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. SAVLVERLGRRhllla.G |
| Chain | Residue | Details |
| A | SER338-GLY354 |
| site_id | PS00217 |
| Number of Residues | 26 |
| Details | SUGAR_TRANSPORT_2 Sugar transport proteins signature 2. VlGVCaGIsysalpmYlgElapknlR |
| Chain | Residue | Details |
| A | VAL140-ARG165 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 240 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 81 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 101 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P11169","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
