9IV8
Cryo-EM structure of human NCX1 in PIP2 diC8 bound state
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 74 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | GLU1-LYS39 | |
| A | GLY123-THR135 | |
| A | SER191-GLU196 | |
| A | VAL812-ASP814 | |
| A | ASN886-PRO896 | |
| A | SER956-SER963 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 200 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE40-ILE60 | |
| A | ILE935-GLY955 | |
| A | LEU102-CYS122 | |
| A | ILE136-PRO156 | |
| A | PHE170-ILE190 | |
| A | VAL197-ALA217 | |
| A | GLY791-SER811 | |
| A | THR815-VAL835 | |
| A | PHE865-ILE885 | |
| A | GLU897-VAL917 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 643 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA61-ASN101 | |
| A | ASP157-PHE169 | |
| A | ASP218-PHE790 | |
| A | THR836-GLN864 | |
| A | LEU918-HIS934 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P23685 |
| Chain | Residue | Details |
| A | ARG410 | |
| A | VAL525 | |
| A | THR541 | |
| A | ASP577 | |
| A | LYS603 | |
| A | ALA604 | |
| A | LEU605 | |
| A | SER708 | |
| A | ASP446 | |
| A | GLU471 | |
| A | ASP472 | |
| A | ILE474 | |
| A | GLU476 | |
| A | HIS479 | |
| A | VAL523 | |
| A | LYS524 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P70414 |
| Chain | Residue | Details |
| A | SER275 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P70414, ECO:0000255 |
| Chain | Residue | Details |
| A | GLN382 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN9 | |
| A | ASN125 |
