9IT2

Cryo-EM structure of urease from Ureaplasma parvum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0009039	molecular_function	urease activity
A	0016787	molecular_function	hydrolase activity
A	0043419	biological_process	urea catabolic process
B	0005737	cellular_component	cytoplasm
B	0009039	molecular_function	urease activity
B	0016787	molecular_function	hydrolase activity
B	0043419	biological_process	urea catabolic process
C	0005737	cellular_component	cytoplasm
C	0009039	molecular_function	urease activity
C	0016151	molecular_function	nickel cation binding
C	0016787	molecular_function	hydrolase activity
C	0043419	biological_process	urea catabolic process
C	0046872	molecular_function	metal ion binding
D	0005737	cellular_component	cytoplasm
D	0009039	molecular_function	urease activity
D	0016787	molecular_function	hydrolase activity
D	0043419	biological_process	urea catabolic process
E	0005737	cellular_component	cytoplasm
E	0009039	molecular_function	urease activity
E	0016787	molecular_function	hydrolase activity
E	0043419	biological_process	urea catabolic process
F	0005737	cellular_component	cytoplasm
F	0009039	molecular_function	urease activity
F	0016151	molecular_function	nickel cation binding
F	0016787	molecular_function	hydrolase activity
F	0043419	biological_process	urea catabolic process
F	0046872	molecular_function	metal ion binding
G	0005737	cellular_component	cytoplasm
G	0009039	molecular_function	urease activity
G	0016787	molecular_function	hydrolase activity
G	0043419	biological_process	urea catabolic process
H	0005737	cellular_component	cytoplasm
H	0009039	molecular_function	urease activity
H	0016787	molecular_function	hydrolase activity
H	0043419	biological_process	urea catabolic process
I	0005737	cellular_component	cytoplasm
I	0009039	molecular_function	urease activity
I	0016151	molecular_function	nickel cation binding
I	0016787	molecular_function	hydrolase activity
I	0043419	biological_process	urea catabolic process
I	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00145
Number of Residues	17
Details	UREASE_2 Urease active site. MVCHHLnpkVpeDVaFA

Chain	Residue	Details
C	MET323-ALA339

---

site_id	PS01120
Number of Residues	14
Details	UREASE_1 Urease nickel ligands signature. TAGGLDtHVHwleP

Chain	Residue	Details
C	THR134-PRO147

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01953","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01953","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"description":"via carbamate group","evidences":[{"source":"HAMAP-Rule","id":"MF_01953","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01953","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---