9IQR

Cryo-EM structure of MT3-alpha2AAR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity

Functional Information from PROSITE/UniProt

site_id	PS00237
Number of Residues	17
Details	G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. SSIvHLCAISLDRYWsI

Chain	Residue	Details
B	SER134-ILE150

---

site_id	PS00272
Number of Residues	21
Details	SNAKE_TOXIN Snake toxins signature. GCaatCPipenydsih.CCktD

Chain	Residue	Details
A	GLY41-ASP61

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	23
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	35
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	19
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	23
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	13
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	23
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Site: {"description":"Implicated in norepinephrine binding","evidences":[{"source":"PubMed","id":"1678850","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Site: {"description":"Implicated in catechol and norepinephrine agonist binding and receptor activation","evidences":[{"source":"PubMed","id":"1678850","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Site: {"description":"Implicated in catechol agonist binding and receptor activation","evidences":[{"source":"PubMed","id":"1678850","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	3
Details	Site: {"description":"Implicated in norepinephrine binding and receptor activation","evidences":[{"source":"PubMed","id":"35245122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---