Functional Information from GO Data
| Chain | GOid | namespace | contents |
| R | 0002430 | biological_process | complement receptor mediated signaling pathway |
| R | 0002684 | biological_process | positive regulation of immune system process |
| R | 0004876 | molecular_function | complement component C3a receptor activity |
| R | 0004878 | molecular_function | complement component C5a receptor activity |
| R | 0004930 | molecular_function | G protein-coupled receptor activity |
| R | 0005886 | cellular_component | plasma membrane |
| R | 0006935 | biological_process | chemotaxis |
| R | 0006954 | biological_process | inflammatory response |
| R | 0007165 | biological_process | signal transduction |
| R | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| R | 0007193 | biological_process | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| R | 0007200 | biological_process | phospholipase C-activating G protein-coupled receptor signaling pathway |
| R | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| R | 0008015 | biological_process | blood circulation |
| R | 0010575 | biological_process | positive regulation of vascular endothelial growth factor production |
| R | 0010759 | biological_process | positive regulation of macrophage chemotaxis |
| R | 0016020 | cellular_component | membrane |
| R | 0019722 | biological_process | calcium-mediated signaling |
| R | 0035577 | cellular_component | azurophil granule membrane |
| R | 0035579 | cellular_component | specific granule membrane |
| R | 0038178 | biological_process | complement component C5a signaling pathway |
| R | 0045766 | biological_process | positive regulation of angiogenesis |
| R | 0090023 | biological_process | positive regulation of neutrophil chemotaxis |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASVfLLTAISLDRCLvV |
| Chain | Residue | Details |
| R | ALA108-VAL124 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 16 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Sulfotyrosine","evidences":[{"source":"PubMed","id":"12871936","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O09047","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
