Functional Information from GO Data
| Chain | GOid | namespace | contents |
| R | 0002430 | biological_process | complement receptor mediated signaling pathway |
| R | 0002684 | biological_process | positive regulation of immune system process |
| R | 0004876 | molecular_function | complement component C3a receptor activity |
| R | 0004878 | molecular_function | complement component C5a receptor activity |
| R | 0004930 | molecular_function | G protein-coupled receptor activity |
| R | 0005886 | cellular_component | plasma membrane |
| R | 0006935 | biological_process | chemotaxis |
| R | 0006954 | biological_process | inflammatory response |
| R | 0007165 | biological_process | signal transduction |
| R | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| R | 0007193 | biological_process | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| R | 0007200 | biological_process | phospholipase C-activating G protein-coupled receptor signaling pathway |
| R | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| R | 0008015 | biological_process | blood circulation |
| R | 0010575 | biological_process | positive regulation of vascular endothelial growth factor production |
| R | 0010759 | biological_process | positive regulation of macrophage chemotaxis |
| R | 0016020 | cellular_component | membrane |
| R | 0019722 | biological_process | calcium-mediated signaling |
| R | 0035577 | cellular_component | azurophil granule membrane |
| R | 0035579 | cellular_component | specific granule membrane |
| R | 0038178 | biological_process | complement component C5a signaling pathway |
| R | 0045766 | biological_process | positive regulation of angiogenesis |
| R | 0090023 | biological_process | positive regulation of neutrophil chemotaxis |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASVfLLTAISLDRCLvV |
| Chain | Residue | Details |
| R | ALA108-VAL124 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| R | TRP1012 | |
| R | ILE1107 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| R | ILE24-TRP46 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 73 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| R | VAL47-ASN57 | |
| R | ASP119-ALA139 | |
| R | GLY439-VAL482 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| R | THR58-ALA80 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 210 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| R | HIS81-LYS96 | |
| R | ARG161-ARG340 | |
| R | LEU401-ASP417 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| R | LEU97-LEU118 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| R | CYS140-TYR160 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| R | LEU341-VAL360 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| R | VAL378-SER400 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| R | HIS418-LEU438 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 3 |
| Details | MOD_RES: Sulfotyrosine => ECO:0000269|PubMed:12871936 |
| Chain | Residue | Details |
| R | TYR174 | |
| R | TYR184 | |
| R | TYR318 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O09047 |
| Chain | Residue | Details |
| R | SER459 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:O09047 |
| Chain | Residue | Details |
| R | THR463 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| R | ASN9 | |
| R | ASN194 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 1 |
| Details | CARBOHYD: O-linked (GalNAc...) serine => ECO:0000269|PubMed:23234360 |
| Chain | Residue | Details |
| R | SER266 |
