9IPW

Crystal structure of VHL-EloB-EloC in complex with a fragment compound 7HC_5(D3)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006368	biological_process	transcription elongation by RNA polymerase II
A	0030891	cellular_component	VCB complex
A	0070449	cellular_component	elongin complex
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0006368	biological_process	transcription elongation by RNA polymerase II
D	0030891	cellular_component	VCB complex
D	0070449	cellular_component	elongin complex
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0006368	biological_process	transcription elongation by RNA polymerase II
G	0030891	cellular_component	VCB complex
G	0070449	cellular_component	elongin complex
H	0006511	biological_process	ubiquitin-dependent protein catabolic process
J	0006368	biological_process	transcription elongation by RNA polymerase II
J	0030891	cellular_component	VCB complex
J	0070449	cellular_component	elongin complex
K	0006511	biological_process	ubiquitin-dependent protein catabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2009","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Waridel P.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P62869","evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI3
Number of Residues	36
Details	Region: {"description":"Interaction with Elongin BC complex"}

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site_id	SWS_FT_FI4
Number of Residues	110
Details	Region: {"description":"Involved in binding to CCT complex"}

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