9IP5

Hemichannel sub-structure of Cx36/GJD2 gap junction intercellular channel (FN conformation) in brain polar lipid nanodiscs, treated with a 14-fold molar excess of carbenoxolone

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042597	cellular_component	periplasmic space
B	0042597	cellular_component	periplasmic space
C	0042597	cellular_component	periplasmic space
D	0042597	cellular_component	periplasmic space
E	0042597	cellular_component	periplasmic space
F	0042597	cellular_component	periplasmic space

Functional Information from PROSITE/UniProt

site_id	PS00407
Number of Residues	14
Details	CONNEXINS_1 Connexins signature 1. CNTlQPGCnqACYD

Chain	Residue	Details
A	CYS55-ASP68

---

site_id	PS00408
Number of Residues	17
Details	CONNEXINS_2 Connexins signature 2. Cnry.PCikeVECYVSRP

Chain	Residue	Details
A	CYS231-PRO247

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	528
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	378
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---