9IMS

Crystal structure of C45 isoprenyl diphosphate synthase Rv0562 variant D98R/D223R from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
A	0004337	molecular_function	(2E,6E)-farnesyl diphosphate synthase activity
A	0004659	molecular_function	prenyltransferase activity
A	0005886	cellular_component	plasma membrane
A	0008299	biological_process	isoprenoid biosynthetic process
A	0033386	biological_process	geranylgeranyl diphosphate biosynthetic process
A	0052924	molecular_function	all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity
B	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
B	0004337	molecular_function	(2E,6E)-farnesyl diphosphate synthase activity
B	0004659	molecular_function	prenyltransferase activity
B	0005886	cellular_component	plasma membrane
B	0008299	biological_process	isoprenoid biosynthetic process
B	0033386	biological_process	geranylgeranyl diphosphate biosynthetic process
B	0052924	molecular_function	all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Motif: {"description":"DDXXD motif","evidences":[{"source":"PubMed","id":"30301210","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q12051","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Important for determining product chain length","evidences":[{"source":"PubMed","id":"30301210","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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