9IJK

The CryoEM structure of a C-C bond hydrolase MhpC homotetramer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0016787	molecular_function	hydrolase activity
A	0018771	molecular_function	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity
A	0019380	biological_process	3-phenylpropionate catabolic process
A	0019622	biological_process	3-(3-hydroxy)phenylpropionate catabolic process
A	0052823	molecular_function	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity
B	0005737	cellular_component	cytoplasm
B	0016787	molecular_function	hydrolase activity
B	0018771	molecular_function	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity
B	0019380	biological_process	3-phenylpropionate catabolic process
B	0019622	biological_process	3-(3-hydroxy)phenylpropionate catabolic process
B	0052823	molecular_function	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity
C	0005737	cellular_component	cytoplasm
C	0016787	molecular_function	hydrolase activity
C	0018771	molecular_function	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity
C	0019380	biological_process	3-phenylpropionate catabolic process
C	0019622	biological_process	3-(3-hydroxy)phenylpropionate catabolic process
C	0052823	molecular_function	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity
D	0005737	cellular_component	cytoplasm
D	0016787	molecular_function	hydrolase activity
D	0018771	molecular_function	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity
D	0019380	biological_process	3-phenylpropionate catabolic process
D	0019622	biological_process	3-(3-hydroxy)phenylpropionate catabolic process
D	0052823	molecular_function	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01654","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15663941","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_01654","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15663941","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Catalytic role in ketonization of the dienol substrate (substrate destabilization)","evidences":[{"source":"HAMAP-Rule","id":"MF_01654","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15663941","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17029402","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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