9IJ3

Cryo-EM Structure of MILI-piRNA-target (26-nt)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006417	biological_process	regulation of translation
A	0007283	biological_process	spermatogenesis
A	0010370	cellular_component	perinucleolar chromocenter
A	0016787	molecular_function	hydrolase activity
A	0030154	biological_process	cell differentiation
A	0030718	biological_process	germ-line stem cell population maintenance
A	0031047	biological_process	regulatory ncRNA-mediated gene silencing
A	0033391	cellular_component	chromatoid body
A	0034584	molecular_function	piRNA binding
A	0034587	biological_process	piRNA processing
A	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
A	0042754	biological_process	negative regulation of circadian rhythm
A	0043186	cellular_component	P granule
A	0046872	molecular_function	metal ion binding
A	0048477	biological_process	oogenesis
A	0048511	biological_process	rhythmic process
A	0051321	biological_process	meiotic cell cycle
A	0060903	biological_process	positive regulation of meiosis I
A	0071546	cellular_component	pi-body
A	0097433	cellular_component	dense body
A	0140965	biological_process	secondary piRNA processing
A	0140966	biological_process	piRNA-mediated heterochromatin formation
A	0140991	biological_process	piRNA-mediated gene silencing by mRNA destabilization
A	0141005	biological_process	transposable element silencing by heterochromatin formation
A	0141006	biological_process	transposable element silencing by piRNA-mediated heterochromatin formation
A	0141008	biological_process	transposable element silencing by mRNA destabilization
A	0141196	biological_process	transposable element silencing by piRNA-mediated DNA methylation
A	1990923	cellular_component	PET complex
A	2000767	biological_process	positive regulation of cytoplasmic translation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"A8D8P8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Symmetric dimethylarginine; by PRMT5","evidences":[{"source":"PubMed","id":"19584108","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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