9IIT
Full length structure of FKP in complex with GTP and GDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0042350 | biological_process | GDP-L-fucose biosynthetic process |
| A | 0042352 | biological_process | GDP-L-fucose salvage |
| A | 0047341 | molecular_function | fucose-1-phosphate guanylyltransferase activity |
| A | 0050201 | molecular_function | fucokinase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0042350 | biological_process | GDP-L-fucose biosynthetic process |
| B | 0042352 | biological_process | GDP-L-fucose salvage |
| B | 0047341 | molecular_function | fucose-1-phosphate guanylyltransferase activity |
| B | 0050201 | molecular_function | fucokinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue GTP A 1001 |
| Chain | Residue |
| A | SER6 |
| A | GLN77 |
| A | SER78 |
| A | ARG79 |
| A | ARG80 |
| A | LYS89 |
| A | SER134 |
| A | HOH1101 |
| A | HOH1103 |
| A | HOH1292 |
| A | ASP31 |
| A | GLY38 |
| A | SER39 |
| A | GLY42 |
| A | HIS73 |
| A | ALA74 |
| A | GLY75 |
| A | GLY76 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue GTP A 1002 |
| Chain | Residue |
| A | PRO95 |
| A | VAL96 |
| A | LEU105 |
| A | LYS300 |
| A | VAL309 |
| A | GLN310 |
| A | ASN311 |
| A | ALA312 |
| A | ASN486 |
| A | LEU490 |
| A | ASN493 |
| A | HOH1114 |
| A | HOH1124 |
| A | HOH1169 |
| A | HOH1221 |
| A | HOH1250 |
| A | HOH1254 |
| A | HOH1268 |
| A | HOH1279 |
| A | HOH1310 |
| A | HOH1313 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue FMT A 1003 |
| Chain | Residue |
| A | ALA505 |
| A | ARG540 |
| A | SER824 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 1004 |
| Chain | Residue |
| A | ASP659 |
| B | ASP659 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue MLA A 1005 |
| Chain | Residue |
| A | GLY713 |
| A | SER714 |
| A | GLY715 |
| A | LEU716 |
| A | GLY717 |
| A | THR718 |
| A | SER719 |
| A | HOH1110 |
| A | HOH1111 |
| A | HOH1115 |
| A | HOH1222 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 1006 |
| Chain | Residue |
| A | SER642 |
| A | ASP644 |
| A | PRO666 |
| A | PHE667 |
| A | PRO670 |
| A | LEU706 |
| A | ALA708 |
| A | LEU722 |
| A | HOH1128 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 1007 |
| Chain | Residue |
| A | ARG592 |
| A | TRP599 |
| A | ASP601 |
| A | GLN761 |
| A | ASP762 |
| A | ALA900 |
| A | HOH1176 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residue GTP B 1001 |
| Chain | Residue |
| B | SER6 |
| B | ASP31 |
| B | GLY38 |
| B | HIS73 |
| B | ALA74 |
| B | GLY75 |
| B | GLY76 |
| B | GLN77 |
| B | SER78 |
| B | ARG79 |
| B | LYS89 |
| B | ASP136 |
| B | HOH1104 |
| B | HOH1160 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue GDP B 1002 |
| Chain | Residue |
| B | HOH1165 |
| B | HOH1192 |
| B | PRO95 |
| B | VAL96 |
| B | LEU105 |
| B | LYS300 |
| B | LYS302 |
| B | VAL309 |
| B | GLN310 |
| B | ASN311 |
| B | ALA312 |
| B | ASN486 |
| B | LEU490 |
| B | ASN493 |
| B | HOH1124 |
| B | HOH1132 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 1003 |
| Chain | Residue |
| B | LEU181 |
| B | SER259 |
| B | VAL260 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue ACT B 1004 |
| Chain | Residue |
| B | GLU19 |
| B | LEU110 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 1005 |
| Chain | Residue |
| B | HIS168 |
| B | GLY169 |
| B | ASP205 |
| B | TYR237 |
| B | HOH1263 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 1006 |
| Chain | Residue |
| B | SER642 |
| B | ASP644 |
| B | PRO666 |
| B | LEU706 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 332 |
| Details | Region: {"description":"Fucose-1-phosphate guanylyltransferase","evidences":[{"source":"PubMed","id":"30242642","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 780 |
| Details | Region: {"description":"L-fucokinase","evidences":[{"source":"PubMed","id":"30242642","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
