9IIO

J-shaped conformer of amyloid beta (1-40)

Functional Information from GO Data

Chain	GOid	namespace	contents
2	0016020	cellular_component	membrane
3	0016020	cellular_component	membrane
4	0016020	cellular_component	membrane
5	0016020	cellular_component	membrane
6	0016020	cellular_component	membrane
a	0016020	cellular_component	membrane
A	0016020	cellular_component	membrane
b	0016020	cellular_component	membrane
B	0016020	cellular_component	membrane
c	0016020	cellular_component	membrane
C	0016020	cellular_component	membrane
d	0016020	cellular_component	membrane
D	0016020	cellular_component	membrane
e	0016020	cellular_component	membrane
E	0016020	cellular_component	membrane
f	0016020	cellular_component	membrane
F	0016020	cellular_component	membrane
g	0016020	cellular_component	membrane
G	0016020	cellular_component	membrane
h	0016020	cellular_component	membrane
H	0016020	cellular_component	membrane
i	0016020	cellular_component	membrane
I	0016020	cellular_component	membrane
J	0016020	cellular_component	membrane
K	0016020	cellular_component	membrane
L	0016020	cellular_component	membrane
M	0016020	cellular_component	membrane
N	0016020	cellular_component	membrane
O	0016020	cellular_component	membrane
P	0016020	cellular_component	membrane
Q	0016020	cellular_component	membrane
R	0016020	cellular_component	membrane
S	0016020	cellular_component	membrane
T	0016020	cellular_component	membrane
U	0016020	cellular_component	membrane
V	0016020	cellular_component	membrane
W	0016020	cellular_component	membrane
X	0016020	cellular_component	membrane
Y	0016020	cellular_component	membrane
Z	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	920
Details	Peptide: {"description":"P3(40)","featureId":"PRO_0000000096"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	80
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11274207","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26898943","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10413512","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"11274207","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10413512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11274207","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26898943","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	40
Details	Site: {"description":"Cleavage; by caspase-6; when associated with variant 670-N-L-671"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	40
Details	Site: {"description":"Cleavage; by ACE","evidences":[{"source":"PubMed","id":"11604391","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16154999","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	40
Details	Site: {"description":"Cleavage; by alpha-secretase","evidences":[{"source":"PubMed","id":"11851430","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	40
Details	Site: {"description":"Cleavage; by theta-secretase","evidences":[{"source":"PubMed","id":"16816112","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	40
Details	Site: {"description":"Implicated in free radical propagation","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	40
Details	Site: {"description":"Susceptible to oxidation","evidences":[{"source":"PubMed","id":"10535332","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	40
Details	Glycosylation: {"description":"O-linked (HexNAc...) tyrosine; partial","evidences":[{"source":"PubMed","id":"22576872","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---