9IHO

Open state without NUQM and without flavoprotein (classification state 4) of Pichia pastoris mitochondrial complex I in cMSP26 nanodiscs

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0022904	biological_process	respiratory electron transport chain
A	0030964	cellular_component	NADH dehydrogenase complex
A	0031966	cellular_component	mitochondrial membrane
A	1902600	biological_process	proton transmembrane transport
B	0005739	cellular_component	mitochondrion
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0009060	biological_process	aerobic respiration
B	0015990	biological_process	electron transport coupled proton transport
B	0016491	molecular_function	oxidoreductase activity
B	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B	0045271	cellular_component	respiratory chain complex I
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0005739	cellular_component	mitochondrion
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	1902600	biological_process	proton transmembrane transport
D	0005739	cellular_component	mitochondrion
D	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
D	0016491	molecular_function	oxidoreductase activity
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0046872	molecular_function	metal ion binding
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	1902600	biological_process	proton transmembrane transport
H	0003954	molecular_function	NADH dehydrogenase activity
H	0005743	cellular_component	mitochondrial inner membrane
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	1902600	biological_process	proton transmembrane transport
I	0003954	molecular_function	NADH dehydrogenase activity
I	0005739	cellular_component	mitochondrion
I	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
I	0009060	biological_process	aerobic respiration
I	0016491	molecular_function	oxidoreductase activity
I	0032981	biological_process	mitochondrial respiratory chain complex I assembly
I	0046872	molecular_function	metal ion binding
I	0051536	molecular_function	iron-sulfur cluster binding
I	0051539	molecular_function	4 iron, 4 sulfur cluster binding
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0016491	molecular_function	oxidoreductase activity
J	0022904	biological_process	respiratory electron transport chain
J	0031966	cellular_component	mitochondrial membrane
J	1902600	biological_process	proton transmembrane transport
K	0016491	molecular_function	oxidoreductase activity
L	0003954	molecular_function	NADH dehydrogenase activity
L	0005743	cellular_component	mitochondrial inner membrane
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0015990	biological_process	electron transport coupled proton transport
L	0016491	molecular_function	oxidoreductase activity
L	0022904	biological_process	respiratory electron transport chain
M	0003954	molecular_function	NADH dehydrogenase activity
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009060	biological_process	aerobic respiration
M	0015990	biological_process	electron transport coupled proton transport
M	0016020	cellular_component	membrane
M	0016491	molecular_function	oxidoreductase activity
M	0022904	biological_process	respiratory electron transport chain
M	0031966	cellular_component	mitochondrial membrane
M	0048039	molecular_function	ubiquinone binding
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0016020	cellular_component	membrane
N	0016491	molecular_function	oxidoreductase activity
N	1902600	biological_process	proton transmembrane transport
O	0016491	molecular_function	oxidoreductase activity
P	0005739	cellular_component	mitochondrion
P	0016491	molecular_function	oxidoreductase activity
P	0044877	molecular_function	protein-containing complex binding
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0016020	cellular_component	membrane
Q	0016491	molecular_function	oxidoreductase activity
Q	0022904	biological_process	respiratory electron transport chain
R	0005739	cellular_component	mitochondrion
R	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
R	0016491	molecular_function	oxidoreductase activity
S	0005743	cellular_component	mitochondrial inner membrane
S	0016491	molecular_function	oxidoreductase activity
S	0022904	biological_process	respiratory electron transport chain
T	0000035	molecular_function	acyl binding
T	0000036	molecular_function	acyl carrier activity
T	0005739	cellular_component	mitochondrion
T	0006629	biological_process	lipid metabolic process
T	0006631	biological_process	fatty acid metabolic process
T	0006633	biological_process	fatty acid biosynthetic process
T	0016491	molecular_function	oxidoreductase activity
U	0000035	molecular_function	acyl binding
U	0000036	molecular_function	acyl carrier activity
U	0005739	cellular_component	mitochondrion
U	0006629	biological_process	lipid metabolic process
U	0006631	biological_process	fatty acid metabolic process
U	0006633	biological_process	fatty acid biosynthetic process
U	0016491	molecular_function	oxidoreductase activity
U	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
V	0005743	cellular_component	mitochondrial inner membrane
V	0016491	molecular_function	oxidoreductase activity
V	0022904	biological_process	respiratory electron transport chain
W	0005743	cellular_component	mitochondrial inner membrane
W	0006979	biological_process	response to oxidative stress
W	0016491	molecular_function	oxidoreductase activity
W	0022904	biological_process	respiratory electron transport chain
X	0005743	cellular_component	mitochondrial inner membrane
X	0016491	molecular_function	oxidoreductase activity
X	0022904	biological_process	respiratory electron transport chain
Y	0016491	molecular_function	oxidoreductase activity
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0016020	cellular_component	membrane
Z	0016491	molecular_function	oxidoreductase activity
Z	0022904	biological_process	respiratory electron transport chain
Z	0045271	cellular_component	respiratory chain complex I
a	0005743	cellular_component	mitochondrial inner membrane
a	0016491	molecular_function	oxidoreductase activity
a	0022904	biological_process	respiratory electron transport chain
b	0016491	molecular_function	oxidoreductase activity
c	0016491	molecular_function	oxidoreductase activity
e	0016491	molecular_function	oxidoreductase activity
f	0016491	molecular_function	oxidoreductase activity
g	0016491	molecular_function	oxidoreductase activity
h	0016491	molecular_function	oxidoreductase activity
i	0016491	molecular_function	oxidoreductase activity
k	0005743	cellular_component	mitochondrial inner membrane
k	0016491	molecular_function	oxidoreductase activity
k	0022904	biological_process	respiratory electron transport chain
k	0032981	biological_process	mitochondrial respiratory chain complex I assembly
l	0016491	molecular_function	oxidoreductase activity
m	0016491	molecular_function	oxidoreductase activity
n	0005743	cellular_component	mitochondrial inner membrane
n	0016491	molecular_function	oxidoreductase activity
n	0022904	biological_process	respiratory electron transport chain
o	0005743	cellular_component	mitochondrial inner membrane
o	0005758	cellular_component	mitochondrial intermembrane space
o	0016491	molecular_function	oxidoreductase activity
o	0022904	biological_process	respiratory electron transport chain
p	0005743	cellular_component	mitochondrial inner membrane
p	0016491	molecular_function	oxidoreductase activity
p	0022904	biological_process	respiratory electron transport chain
q	0005743	cellular_component	mitochondrial inner membrane
q	0006979	biological_process	response to oxidative stress
q	0016491	molecular_function	oxidoreductase activity
q	0022904	biological_process	respiratory electron transport chain

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGMDSLDLNDALVAL

Chain	Residue	Details
T	ASP81-LEU96

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
I	CYS123-PRO134
I	CYS162-PRO173

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEsK

Chain	Residue	Details
D	LEU135-LYS146

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREtyDLFgiffegHpdlRrIM

Chain	Residue	Details
C	GLU185-MET206

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PryCYheklavaGnCRmC

Chain	Residue	Details
G	PRO56-CYS73

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPvCDqGGeCdLQ

Chain	Residue	Details
G	CYS123-GLN135

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIhCtRCVrF

Chain	Residue	Details
G	ARG172-PHE182

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GVLMaVaDALKLLsKE

Chain	Residue	Details
H	GLY56-GLU71

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDNVEAEseLVs.G

Chain	Residue	Details
H	PRO211-GLY224

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GvDRIVPVDIYvPgCPP

Chain	Residue	Details
B	GLY159-PRO175

---