9I88

Structure of the wild-type Staphylococcus aureus 70S ribosome complexed with clincelin

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0006412	biological_process	translation
1	0019843	molecular_function	rRNA binding
2	0006412	biological_process	translation
2	0022625	cellular_component	cytosolic large ribosomal subunit
3	0006412	biological_process	translation
3	0022625	cellular_component	cytosolic large ribosomal subunit
4	0006412	biological_process	translation
5	0006412	biological_process	translation
6	0005737	cellular_component	cytoplasm
6	0006412	biological_process	translation
6	0019843	molecular_function	rRNA binding
7	0006412	biological_process	translation
8	0003735	molecular_function	structural constituent of ribosome
8	0006412	biological_process	translation
8	0015934	cellular_component	large ribosomal subunit
8	0022625	cellular_component	cytosolic large ribosomal subunit
9	0005737	cellular_component	cytoplasm
9	0006412	biological_process	translation
9	0008270	molecular_function	zinc ion binding
9	0019843	molecular_function	rRNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0006412	biological_process	translation
c	0022627	cellular_component	cytosolic small ribosomal subunit
d	0003729	molecular_function	mRNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0006412	biological_process	translation
d	0019843	molecular_function	rRNA binding
d	0022627	cellular_component	cytosolic small ribosomal subunit
e	0003735	molecular_function	structural constituent of ribosome
e	0006412	biological_process	translation
e	0015935	cellular_component	small ribosomal subunit
e	0019843	molecular_function	rRNA binding
e	0042274	biological_process	ribosomal small subunit biogenesis
f	0005737	cellular_component	cytoplasm
f	0006412	biological_process	translation
f	0019843	molecular_function	rRNA binding
f	0042254	biological_process	ribosome biogenesis
g	0003735	molecular_function	structural constituent of ribosome
g	0005737	cellular_component	cytoplasm
g	0006412	biological_process	translation
g	0019843	molecular_function	rRNA binding
g	0070181	molecular_function	small ribosomal subunit rRNA binding
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0006412	biological_process	translation
G	0015934	cellular_component	large ribosomal subunit
G	0019843	molecular_function	rRNA binding
h	0000049	molecular_function	tRNA binding
h	0006412	biological_process	translation
h	0019843	molecular_function	rRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
H	0022625	cellular_component	cytosolic large ribosomal subunit
i	0005737	cellular_component	cytoplasm
i	0006412	biological_process	translation
i	0019843	molecular_function	rRNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
j	0003723	molecular_function	RNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005737	cellular_component	cytoplasm
j	0006412	biological_process	translation
j	0015935	cellular_component	small ribosomal subunit
j	0022627	cellular_component	cytosolic small ribosomal subunit
J	0000049	molecular_function	tRNA binding
J	0006412	biological_process	translation
J	0019843	molecular_function	rRNA binding
k	0000049	molecular_function	tRNA binding
k	0005737	cellular_component	cytoplasm
k	0006412	biological_process	translation
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0006412	biological_process	translation
K	0019843	molecular_function	rRNA binding
K	0022625	cellular_component	cytosolic large ribosomal subunit
l	0006412	biological_process	translation
l	0019843	molecular_function	rRNA binding
m	0000049	molecular_function	tRNA binding
m	0006412	biological_process	translation
m	0019843	molecular_function	rRNA binding
M	0003729	molecular_function	mRNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0017148	biological_process	negative regulation of translation
M	0022625	cellular_component	cytosolic large ribosomal subunit
n	0000049	molecular_function	tRNA binding
n	0005829	cellular_component	cytosol
n	0006412	biological_process	translation
n	0015935	cellular_component	small ribosomal subunit
n	0019843	molecular_function	rRNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0006412	biological_process	translation
N	0019843	molecular_function	rRNA binding
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	0070180	molecular_function	large ribosomal subunit rRNA binding
o	0003735	molecular_function	structural constituent of ribosome
o	0006412	biological_process	translation
o	0008270	molecular_function	zinc ion binding
o	0015935	cellular_component	small ribosomal subunit
o	0019843	molecular_function	rRNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0006412	biological_process	translation
O	0019843	molecular_function	rRNA binding
O	0022625	cellular_component	cytosolic large ribosomal subunit
p	0005737	cellular_component	cytoplasm
p	0006412	biological_process	translation
p	0019843	molecular_function	rRNA binding
p	0022627	cellular_component	cytosolic small ribosomal subunit
P	0003735	molecular_function	structural constituent of ribosome
P	0006412	biological_process	translation
P	0019843	molecular_function	rRNA binding
P	0022625	cellular_component	cytosolic large ribosomal subunit
q	0003735	molecular_function	structural constituent of ribosome
q	0005737	cellular_component	cytoplasm
q	0006412	biological_process	translation
q	0015935	cellular_component	small ribosomal subunit
Q	0003735	molecular_function	structural constituent of ribosome
Q	0006412	biological_process	translation
Q	0015934	cellular_component	large ribosomal subunit
Q	0022625	cellular_component	cytosolic large ribosomal subunit
r	0003735	molecular_function	structural constituent of ribosome
r	0006412	biological_process	translation
r	0019843	molecular_function	rRNA binding
r	0022627	cellular_component	cytosolic small ribosomal subunit
R	0005737	cellular_component	cytoplasm
R	0006412	biological_process	translation
R	0008097	molecular_function	5S rRNA binding
R	0019843	molecular_function	rRNA binding
R	0022625	cellular_component	cytosolic large ribosomal subunit
s	0003735	molecular_function	structural constituent of ribosome
s	0006412	biological_process	translation
s	0019843	molecular_function	rRNA binding
s	0022627	cellular_component	cytosolic small ribosomal subunit
s	0070181	molecular_function	small ribosomal subunit rRNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0006412	biological_process	translation
S	0022625	cellular_component	cytosolic large ribosomal subunit
t	0000028	biological_process	ribosomal small subunit assembly
t	0003735	molecular_function	structural constituent of ribosome
t	0005737	cellular_component	cytoplasm
t	0006412	biological_process	translation
t	0019843	molecular_function	rRNA binding
T	0000027	biological_process	ribosomal large subunit assembly
T	0019843	molecular_function	rRNA binding
u	0005829	cellular_component	cytosol
u	0006412	biological_process	translation
u	0015935	cellular_component	small ribosomal subunit
u	0019843	molecular_function	rRNA binding
u	0070181	molecular_function	small ribosomal subunit rRNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005737	cellular_component	cytoplasm
U	0006412	biological_process	translation
U	0019843	molecular_function	rRNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0006412	biological_process	translation
V	0015934	cellular_component	large ribosomal subunit
V	0019843	molecular_function	rRNA binding
V	0022625	cellular_component	cytosolic large ribosomal subunit
W	0006412	biological_process	translation
W	0019843	molecular_function	rRNA binding
X	0006412	biological_process	translation
X	0019843	molecular_function	rRNA binding
Y	0003723	molecular_function	RNA binding
Y	0006412	biological_process	translation
Y	0008097	molecular_function	5S rRNA binding
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0003735	molecular_function	structural constituent of ribosome
Z	0006412	biological_process	translation
Z	0022625	cellular_component	cytosolic large ribosomal subunit

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVIVrtksgvrrn.DGsyikFdeNacVI

Chain	Residue	Details
N	ALA60-ILE86

---

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SkLvtkLInkimldGKRgtaqrILysA

Chain	Residue	Details
h	SER20-ALA46

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaLVSTSeGVItdkeAR

Chain	Residue	Details
i	GLY102-ARG119

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALqsA.GLeVtairDvTPvPHN

Chain	Residue	Details
l	ILE97-ASN119

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
m	LYS56-ARG63

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVkIqEtRPLS

Chain	Residue	Details
r	GLY58-SER70

---

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.TelLkrFISEr.GKIlprRV

Chain	Residue	Details
s	ILE26-VAL49

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. DGRkhvpvyVtedmVGhkLGEFapT

Chain	Residue	Details
t	ASP53-THR77

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LelITGQkpLvTkAKkS

Chain	Residue	Details
J	LEU57-SER73

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGftGQaqAirhGiARAL

Chain	Residue	Details
j	GLY71-LEU89

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrsGAdvsGPIpLPT

Chain	Residue	Details
k	ALA29-THR44

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VneHLrthKkDhhSrrgLlkMvgrrrhLlnY

Chain	Residue	Details
p	VAL39-TYR69

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KrfRpRAqGRasainkrtSHITIvV

Chain	Residue	Details
V	LYS83-VAL107

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGSVmNPnD

Chain	Residue	Details
G	PRO218-ASP229

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FvagdviDvtGvSkGKGfqGaikR

Chain	Residue	Details
H	PHE110-ARG133

---

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGnGsLdkk..LtVkahkFSasAaeaIdakG

Chain	Residue	Details
O	LYS110-GLY140

---

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGI

Chain	Residue	Details
K	PRO154-ILE162

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CercgrphsvyrkFKLCRiCFR

Chain	Residue	Details
o	ARG23-ARG45

---

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARaeqyseGtVplHt..LradIDyahaeadTtyGklG

Chain	Residue	Details
d	ALA162-GLY196

---

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YiTtKNkrnnPerIEmkKYC

Chain	Residue	Details
6	TYR17-CYS36

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfrFtAlvVVGDkn.GrVGfGtgkaq.EVpe.AI

Chain	Residue	Details
f	GLY28-ILE60

---

site_id	PS00586
Number of Residues	12
Details	RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKVWIKIFP

Chain	Residue	Details
P	LYS59-PRO70

---

site_id	PS00591
Number of Residues	11
Details	GH10_1 Glycosyl hydrolases family 10 (GH10) active site. AIEVdITELNI

Chain	Residue	Details
Y	ALA140-ILE150

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LAsRLdavVYSlglArTrrqARqLV

Chain	Residue	Details
e	LEU90-VAL114

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHrrGlpVRGQ

Chain	Residue	Details
n	ARG87-GLN100

---

site_id	PS00701
Number of Residues	12
Details	RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGaGKGavegW

Chain	Residue	Details
P	ARG82-TRP93

---

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. IKGMLPstrl.GEkqgkkLfVYgG

Chain	Residue	Details
M	ILE106-GLY128

---

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTYQpnkrkHskvh.GFrkR

Chain	Residue	Details
7	LYS3-ARG22

---

site_id	PS00828
Number of Residues	26
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CekCkvIkRkgkVmViCenp.KHkQrQ

Chain	Residue	Details
9	CYS11-GLN36

---

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GsILyRQRGtkiypG

Chain	Residue	Details
Z	GLY42-GLY56

---

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHrGAaKRVkrtasgqlkrsraft.SH

Chain	Residue	Details
8	LYS5-HIS31

---

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrdfRkLWITRINaaaR

Chain	Residue	Details
T	LYS54-ARG70

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. MkQLLEAGVHFG

Chain	Residue	Details
c	MET6-GLY17

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PqaLFVvDprkErnaIaEarklNIP

Chain	Residue	Details
c	PRO158-PRO182

---

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGKVR.RAKLYYLR

Chain	Residue	Details
S	VAL88-ARG103

---

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GkRRLAYeIN

Chain	Residue	Details
g	GLY44-ASN53

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDnVkVIaGkdKGke.GkV

Chain	Residue	Details
X	GLY6-VAL23

---

site_id	PS01143
Number of Residues	22
Details	RIBOSOMAL_L31 Ribosomal protein L31 signature. DIssdsHPFYTgrqkfaaad....GR

Chain	Residue	Details
4	ASP49-ARG70

---

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IeTTeaRaKevrsvvEkLITlGK

Chain	Residue	Details
Q	ILE30-LYS52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	41
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00251","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	155
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	17
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	10
Details	Compositional bias: {"description":"Gly residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	68
Details	Domain: {"description":"KH type-2","evidences":[{"source":"HAMAP-Rule","id":"MF_01309","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	63
Details	Domain: {"description":"S4 RNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01306","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	63
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"HAMAP-Rule","id":"MF_01307","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"3-methylthioaspartic acid","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01364","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---