9I3K

Asymmetric cryo-EM reconstruction of the full-length E. coli transmembrane formate transporter FocA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0010447	biological_process	response to acidic pH
A	0015499	molecular_function	formate transmembrane transporter activity
A	0015724	biological_process	formate transport
A	0019664	biological_process	mixed acid fermentation
A	0042802	molecular_function	identical protein binding
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0010447	biological_process	response to acidic pH
B	0015499	molecular_function	formate transmembrane transporter activity
B	0015724	biological_process	formate transport
B	0019664	biological_process	mixed acid fermentation
B	0042802	molecular_function	identical protein binding
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0010447	biological_process	response to acidic pH
C	0015499	molecular_function	formate transmembrane transporter activity
C	0015724	biological_process	formate transport
C	0019664	biological_process	mixed acid fermentation
C	0042802	molecular_function	identical protein binding
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0010447	biological_process	response to acidic pH
D	0015499	molecular_function	formate transmembrane transporter activity
D	0015724	biological_process	formate transport
D	0019664	biological_process	mixed acid fermentation
D	0042802	molecular_function	identical protein binding
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0010447	biological_process	response to acidic pH
E	0015499	molecular_function	formate transmembrane transporter activity
E	0015724	biological_process	formate transport
E	0019664	biological_process	mixed acid fermentation
E	0042802	molecular_function	identical protein binding

Functional Information from PROSITE/UniProt

site_id	PS01005
Number of Residues	10
Details	FORMATE_NITRITE_TP_1 Formate and nitrite transporters signature 1. VVcGADLFTS

Chain	Residue	Details
A	VAL83-SER92

---

site_id	PS01006
Number of Residues	11
Details	FORMATE_NITRITE_TP_2 Formate and nitrite transporters signature 2. GilANLMVCLA

Chain	Residue	Details
A	GLY168-ALA178

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	650
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"UniProtKB","id":"P0AC25","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	370
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"UniProtKB","id":"P0AC25","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	155
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"UniProtKB","id":"P0AC25","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	Site: {"description":"Important for formate translocation","evidences":[{"source":"PubMed","id":"35390794","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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