9HVO
Structure of the transcribing Pol II-RECQL5 complex
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DNDPSDYVEqdDI |
| Chain | Residue | Details |
| C | ASP136-ILE148 |
| site_id | PS00115 |
| Number of Residues | 7 |
| Details | RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA |
| Chain | Residue | Details |
| A | TYR1593-ALA1599 | |
| A | TYR1671-SER1677 | |
| A | TYR1678-SER1684 | |
| A | TYR1685-SER1691 | |
| A | TYR1692-SER1698 | |
| A | TYR1699-SER1705 | |
| A | TYR1706-SER1712 | |
| A | TYR1713-SER1719 | |
| A | TYR1720-SER1726 | |
| A | TYR1727-SER1733 | |
| A | TYR1734-SER1740 | |
| A | TYR1615-SER1621 | |
| A | TYR1741-ASN1747 | |
| A | TYR1748-ASN1754 | |
| A | TYR1755-SER1761 | |
| A | TYR1762-SER1768 | |
| A | TYR1769-ASN1775 | |
| A | TYR1776-ASN1782 | |
| A | TYR1783-SER1789 | |
| A | TYR1790-SER1796 | |
| A | TYR1797-SER1803 | |
| A | TYR1818-SER1824 | |
| A | TYR1622-SER1628 | |
| A | TYR1825-SER1831 | |
| A | TYR1832-LYS1838 | |
| A | TYR1839-SER1845 | |
| A | TYR1853-LYS1859 | |
| A | TYR1860-LYS1866 | |
| A | TYR1867-LYS1873 | |
| A | TYR1874-THR1880 | |
| A | TYR1888-THR1894 | |
| A | TYR1902-LYS1908 | |
| A | TYR1909-THR1915 | |
| A | TYR1629-ASN1635 | |
| A | TYR1916-LYS1922 | |
| A | TYR1923-THR1929 | |
| A | TYR1930-LYS1936 | |
| A | TYR1947-THR1953 | |
| A | TYR1636-SER1642 | |
| A | TYR1643-SER1649 | |
| A | TYR1650-SER1656 | |
| A | TYR1657-SER1663 | |
| A | TYR1664-SER1670 |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH |
| Chain | Residue | Details |
| I | TYR112-HIS118 |
| site_id | PS00446 |
| Number of Residues | 41 |
| Details | RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRvfiaevpiiAidwVqidaNsSvlhDEfIAhRLGLIP |
| Chain | Residue | Details |
| C | ASN32-PRO72 |
| site_id | PS00466 |
| Number of Residues | 38 |
| Details | ZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW |
| Chain | Residue | Details |
| I | CYS86-TRP123 |
| site_id | PS00690 |
| Number of Residues | 10 |
| Details | DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SyLVVDEAHC |
| Chain | Residue | Details |
| O | SER152-CYS161 |
| site_id | PS01030 |
| Number of Residues | 27 |
| Details | RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCQECNNMLypkedkenrillyaCrnC |
| Chain | Residue | Details |
| I | PHE16-CYS42 |
| site_id | PS01110 |
| Number of Residues | 14 |
| Details | RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtkEE |
| Chain | Residue | Details |
| E | HIS142-GLU155 |
| site_id | PS01111 |
| Number of Residues | 15 |
| Details | RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ |
| Chain | Residue | Details |
| F | THR58-GLN72 |
| site_id | PS01112 |
| Number of Residues | 10 |
| Details | RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG |
| Chain | Residue | Details |
| J | ILE2-GLY11 |
| site_id | PS01154 |
| Number of Residues | 32 |
| Details | RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. InkEdHTLgNiIksqLlkdpqVlfagYkvpHP |
| Chain | Residue | Details |
| K | ILE35-PRO66 |
| site_id | PS01166 |
| Number of Residues | 13 |
| Details | RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT |
| Chain | Residue | Details |
| B | GLY932-THR944 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI10 |
| Number of Residues | 25 |
| Details | Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 42 |
| Details | Zinc finger: {"description":"TFIIS-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10145","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
