9HHY

Crystal Structure of the Coxiella burnetii 2-methylisocitrate lyase Bound to Inhibitor Isocitric Acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
A	0046421	molecular_function	methylisocitrate lyase activity
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
B	0046421	molecular_function	methylisocitrate lyase activity
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
C	0046421	molecular_function	methylisocitrate lyase activity
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
D	0046421	molecular_function	methylisocitrate lyase activity
E	0000287	molecular_function	magnesium ion binding
E	0003824	molecular_function	catalytic activity
E	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
E	0046421	molecular_function	methylisocitrate lyase activity
F	0000287	molecular_function	magnesium ion binding
F	0003824	molecular_function	catalytic activity
F	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
F	0046421	molecular_function	methylisocitrate lyase activity
G	0000287	molecular_function	magnesium ion binding
G	0003824	molecular_function	catalytic activity
G	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
G	0046421	molecular_function	methylisocitrate lyase activity
H	0000287	molecular_function	magnesium ion binding
H	0003824	molecular_function	catalytic activity
H	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
H	0046421	molecular_function	methylisocitrate lyase activity
I	0000287	molecular_function	magnesium ion binding
I	0003824	molecular_function	catalytic activity
I	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
I	0046421	molecular_function	methylisocitrate lyase activity
J	0000287	molecular_function	magnesium ion binding
J	0003824	molecular_function	catalytic activity
J	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
J	0046421	molecular_function	methylisocitrate lyase activity
K	0000287	molecular_function	magnesium ion binding
K	0003824	molecular_function	catalytic activity
K	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
K	0046421	molecular_function	methylisocitrate lyase activity
L	0000287	molecular_function	magnesium ion binding
L	0003824	molecular_function	catalytic activity
L	0019629	biological_process	obsolete propionate catabolic process, 2-methylcitrate cycle
L	0046421	molecular_function	methylisocitrate lyase activity

Functional Information from PROSITE/UniProt

site_id	PS00161
Number of Residues	6
Details	ISOCITRATE_LYASE Isocitrate lyase signature. KRCGHR

Chain	Residue	Details
A	LYS116-ARG121

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