9HG2

Crystal structure of M. smegmatis GMP reductase in complex with IMP and ATP.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0003920	molecular_function	GMP reductase activity
A	0003938	molecular_function	IMP dehydrogenase activity
A	0005829	cellular_component	cytosol
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0032264	biological_process	IMP salvage
B	0003824	molecular_function	catalytic activity
B	0003920	molecular_function	GMP reductase activity
B	0003938	molecular_function	IMP dehydrogenase activity
B	0005829	cellular_component	cytosol
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0032264	biological_process	IMP salvage
C	0003824	molecular_function	catalytic activity
C	0003920	molecular_function	GMP reductase activity
C	0003938	molecular_function	IMP dehydrogenase activity
C	0005829	cellular_component	cytosol
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0032264	biological_process	IMP salvage
D	0003824	molecular_function	catalytic activity
D	0003920	molecular_function	GMP reductase activity
D	0003938	molecular_function	IMP dehydrogenase activity
D	0005829	cellular_component	cytosol
D	0006164	biological_process	purine nucleotide biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0032264	biological_process	IMP salvage
E	0003824	molecular_function	catalytic activity
E	0003920	molecular_function	GMP reductase activity
E	0003938	molecular_function	IMP dehydrogenase activity
E	0005829	cellular_component	cytosol
E	0006164	biological_process	purine nucleotide biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0032264	biological_process	IMP salvage
F	0003824	molecular_function	catalytic activity
F	0003920	molecular_function	GMP reductase activity
F	0003938	molecular_function	IMP dehydrogenase activity
F	0005829	cellular_component	cytosol
F	0006164	biological_process	purine nucleotide biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0032264	biological_process	IMP salvage
G	0003824	molecular_function	catalytic activity
G	0003920	molecular_function	GMP reductase activity
G	0003938	molecular_function	IMP dehydrogenase activity
G	0005829	cellular_component	cytosol
G	0006164	biological_process	purine nucleotide biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
G	0032264	biological_process	IMP salvage
H	0003824	molecular_function	catalytic activity
H	0003920	molecular_function	GMP reductase activity
H	0003938	molecular_function	IMP dehydrogenase activity
H	0005829	cellular_component	cytosol
H	0006164	biological_process	purine nucleotide biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0032264	biological_process	IMP salvage
I	0003824	molecular_function	catalytic activity
I	0003920	molecular_function	GMP reductase activity
I	0003938	molecular_function	IMP dehydrogenase activity
I	0005829	cellular_component	cytosol
I	0006164	biological_process	purine nucleotide biosynthetic process
I	0016491	molecular_function	oxidoreductase activity
I	0032264	biological_process	IMP salvage
J	0003824	molecular_function	catalytic activity
J	0003920	molecular_function	GMP reductase activity
J	0003938	molecular_function	IMP dehydrogenase activity
J	0005829	cellular_component	cytosol
J	0006164	biological_process	purine nucleotide biosynthetic process
J	0016491	molecular_function	oxidoreductase activity
J	0032264	biological_process	IMP salvage
K	0003824	molecular_function	catalytic activity
K	0003920	molecular_function	GMP reductase activity
K	0003938	molecular_function	IMP dehydrogenase activity
K	0005829	cellular_component	cytosol
K	0006164	biological_process	purine nucleotide biosynthetic process
K	0016491	molecular_function	oxidoreductase activity
K	0032264	biological_process	IMP salvage
L	0003824	molecular_function	catalytic activity
L	0003920	molecular_function	GMP reductase activity
L	0003938	molecular_function	IMP dehydrogenase activity
L	0005829	cellular_component	cytosol
L	0006164	biological_process	purine nucleotide biosynthetic process
L	0016491	molecular_function	oxidoreductase activity
L	0032264	biological_process	IMP salvage
M	0003824	molecular_function	catalytic activity
M	0003920	molecular_function	GMP reductase activity
M	0003938	molecular_function	IMP dehydrogenase activity
M	0005829	cellular_component	cytosol
M	0006164	biological_process	purine nucleotide biosynthetic process
M	0016491	molecular_function	oxidoreductase activity
M	0032264	biological_process	IMP salvage
N	0003824	molecular_function	catalytic activity
N	0003920	molecular_function	GMP reductase activity
N	0003938	molecular_function	IMP dehydrogenase activity
N	0005829	cellular_component	cytosol
N	0006164	biological_process	purine nucleotide biosynthetic process
N	0016491	molecular_function	oxidoreductase activity
N	0032264	biological_process	IMP salvage
O	0003824	molecular_function	catalytic activity
O	0003920	molecular_function	GMP reductase activity
O	0003938	molecular_function	IMP dehydrogenase activity
O	0005829	cellular_component	cytosol
O	0006164	biological_process	purine nucleotide biosynthetic process
O	0016491	molecular_function	oxidoreductase activity
O	0032264	biological_process	IMP salvage
P	0003824	molecular_function	catalytic activity
P	0003920	molecular_function	GMP reductase activity
P	0003938	molecular_function	IMP dehydrogenase activity
P	0005829	cellular_component	cytosol
P	0006164	biological_process	purine nucleotide biosynthetic process
P	0016491	molecular_function	oxidoreductase activity
P	0032264	biological_process	IMP salvage

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	912
Details	Domain: {"description":"CBS 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	928
Details	Domain: {"description":"CBS 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Active site: {"description":"Thioimidate intermediate","evidences":[{"source":"UniProtKB","id":"P50097","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	64
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P50097","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---