9H5T

ATP-bound human mitochondrial Hsp60-Hsp10 half football complex (C1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001530	molecular_function	lipopolysaccharide binding
A	0001819	biological_process	positive regulation of cytokine production
A	0002039	molecular_function	p53 binding
A	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
A	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
A	0003688	molecular_function	DNA replication origin binding
A	0003697	molecular_function	single-stranded DNA binding
A	0003723	molecular_function	RNA binding
A	0003725	molecular_function	double-stranded RNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005759	cellular_component	mitochondrial matrix
A	0005769	cellular_component	early endosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0005905	cellular_component	clathrin-coated pit
A	0006457	biological_process	protein folding
A	0006458	biological_process	'de novo' protein folding
A	0006986	biological_process	response to unfolded protein
A	0008035	molecular_function	high-density lipoprotein particle binding
A	0008637	biological_process	apoptotic mitochondrial changes
A	0009409	biological_process	response to cold
A	0009986	cellular_component	cell surface
A	0016020	cellular_component	membrane
A	0016853	molecular_function	isomerase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0019899	molecular_function	enzyme binding
A	0030135	cellular_component	coated vesicle
A	0030141	cellular_component	secretory granule
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032727	biological_process	positive regulation of interferon-alpha production
A	0032729	biological_process	positive regulation of type II interferon production
A	0032733	biological_process	positive regulation of interleukin-10 production
A	0032735	biological_process	positive regulation of interleukin-12 production
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0032991	cellular_component	protein-containing complex
A	0034185	molecular_function	apolipoprotein binding
A	0034186	molecular_function	apolipoprotein A-I binding
A	0034514	biological_process	mitochondrial unfolded protein response
A	0042026	biological_process	protein refolding
A	0042100	biological_process	B cell proliferation
A	0042110	biological_process	T cell activation
A	0042113	biological_process	B cell activation
A	0043032	biological_process	positive regulation of macrophage activation
A	0043066	biological_process	negative regulation of apoptotic process
A	0044406	biological_process	adhesion of symbiont to host
A	0045041	biological_process	protein import into mitochondrial intermembrane space
A	0046696	cellular_component	lipopolysaccharide receptor complex
A	0048291	biological_process	isotype switching to IgG isotypes
A	0050821	biological_process	protein stabilization
A	0050870	biological_process	positive regulation of T cell activation
A	0051082	molecular_function	unfolded protein binding
A	0051087	molecular_function	protein-folding chaperone binding
A	0051131	biological_process	chaperone-mediated protein complex assembly
A	0051604	biological_process	protein maturation
A	0051702	biological_process	biological process involved in interaction with symbiont
A	0070062	cellular_component	extracellular exosome
A	0097225	cellular_component	sperm midpiece
A	0140494	cellular_component	migrasome
A	0140608	molecular_function	cysteine-type endopeptidase activator activity
A	1900118	biological_process	negative regulation of execution phase of apoptosis
A	1900119	biological_process	positive regulation of execution phase of apoptosis
B	0000166	molecular_function	nucleotide binding
B	0001530	molecular_function	lipopolysaccharide binding
B	0001819	biological_process	positive regulation of cytokine production
B	0002039	molecular_function	p53 binding
B	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
B	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
B	0003688	molecular_function	DNA replication origin binding
B	0003697	molecular_function	single-stranded DNA binding
B	0003723	molecular_function	RNA binding
B	0003725	molecular_function	double-stranded RNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005615	cellular_component	extracellular space
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005759	cellular_component	mitochondrial matrix
B	0005769	cellular_component	early endosome
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005905	cellular_component	clathrin-coated pit
B	0006457	biological_process	protein folding
B	0006458	biological_process	'de novo' protein folding
B	0006986	biological_process	response to unfolded protein
B	0008035	molecular_function	high-density lipoprotein particle binding
B	0008637	biological_process	apoptotic mitochondrial changes
B	0009409	biological_process	response to cold
B	0009986	cellular_component	cell surface
B	0016020	cellular_component	membrane
B	0016853	molecular_function	isomerase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0019899	molecular_function	enzyme binding
B	0030135	cellular_component	coated vesicle
B	0030141	cellular_component	secretory granule
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032727	biological_process	positive regulation of interferon-alpha production
B	0032729	biological_process	positive regulation of type II interferon production
B	0032733	biological_process	positive regulation of interleukin-10 production
B	0032735	biological_process	positive regulation of interleukin-12 production
B	0032755	biological_process	positive regulation of interleukin-6 production
B	0032991	cellular_component	protein-containing complex
B	0034185	molecular_function	apolipoprotein binding
B	0034186	molecular_function	apolipoprotein A-I binding
B	0034514	biological_process	mitochondrial unfolded protein response
B	0042026	biological_process	protein refolding
B	0042100	biological_process	B cell proliferation
B	0042110	biological_process	T cell activation
B	0042113	biological_process	B cell activation
B	0043032	biological_process	positive regulation of macrophage activation
B	0043066	biological_process	negative regulation of apoptotic process
B	0044406	biological_process	adhesion of symbiont to host
B	0045041	biological_process	protein import into mitochondrial intermembrane space
B	0046696	cellular_component	lipopolysaccharide receptor complex
B	0048291	biological_process	isotype switching to IgG isotypes
B	0050821	biological_process	protein stabilization
B	0050870	biological_process	positive regulation of T cell activation
B	0051082	molecular_function	unfolded protein binding
B	0051087	molecular_function	protein-folding chaperone binding
B	0051131	biological_process	chaperone-mediated protein complex assembly
B	0051604	biological_process	protein maturation
B	0051702	biological_process	biological process involved in interaction with symbiont
B	0070062	cellular_component	extracellular exosome
B	0097225	cellular_component	sperm midpiece
B	0140494	cellular_component	migrasome
B	0140608	molecular_function	cysteine-type endopeptidase activator activity
B	1900118	biological_process	negative regulation of execution phase of apoptosis
B	1900119	biological_process	positive regulation of execution phase of apoptosis
C	0000166	molecular_function	nucleotide binding
C	0001530	molecular_function	lipopolysaccharide binding
C	0001819	biological_process	positive regulation of cytokine production
C	0002039	molecular_function	p53 binding
C	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
C	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
C	0003688	molecular_function	DNA replication origin binding
C	0003697	molecular_function	single-stranded DNA binding
C	0003723	molecular_function	RNA binding
C	0003725	molecular_function	double-stranded RNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005615	cellular_component	extracellular space
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005759	cellular_component	mitochondrial matrix
C	0005769	cellular_component	early endosome
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0005905	cellular_component	clathrin-coated pit
C	0006457	biological_process	protein folding
C	0006458	biological_process	'de novo' protein folding
C	0006986	biological_process	response to unfolded protein
C	0008035	molecular_function	high-density lipoprotein particle binding
C	0008637	biological_process	apoptotic mitochondrial changes
C	0009409	biological_process	response to cold
C	0009986	cellular_component	cell surface
C	0016020	cellular_component	membrane
C	0016853	molecular_function	isomerase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0019899	molecular_function	enzyme binding
C	0030135	cellular_component	coated vesicle
C	0030141	cellular_component	secretory granule
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0032727	biological_process	positive regulation of interferon-alpha production
C	0032729	biological_process	positive regulation of type II interferon production
C	0032733	biological_process	positive regulation of interleukin-10 production
C	0032735	biological_process	positive regulation of interleukin-12 production
C	0032755	biological_process	positive regulation of interleukin-6 production
C	0032991	cellular_component	protein-containing complex
C	0034185	molecular_function	apolipoprotein binding
C	0034186	molecular_function	apolipoprotein A-I binding
C	0034514	biological_process	mitochondrial unfolded protein response
C	0042026	biological_process	protein refolding
C	0042100	biological_process	B cell proliferation
C	0042110	biological_process	T cell activation
C	0042113	biological_process	B cell activation
C	0043032	biological_process	positive regulation of macrophage activation
C	0043066	biological_process	negative regulation of apoptotic process
C	0044406	biological_process	adhesion of symbiont to host
C	0045041	biological_process	protein import into mitochondrial intermembrane space
C	0046696	cellular_component	lipopolysaccharide receptor complex
C	0048291	biological_process	isotype switching to IgG isotypes
C	0050821	biological_process	protein stabilization
C	0050870	biological_process	positive regulation of T cell activation
C	0051082	molecular_function	unfolded protein binding
C	0051087	molecular_function	protein-folding chaperone binding
C	0051131	biological_process	chaperone-mediated protein complex assembly
C	0051604	biological_process	protein maturation
C	0051702	biological_process	biological process involved in interaction with symbiont
C	0070062	cellular_component	extracellular exosome
C	0097225	cellular_component	sperm midpiece
C	0140494	cellular_component	migrasome
C	0140608	molecular_function	cysteine-type endopeptidase activator activity
C	1900118	biological_process	negative regulation of execution phase of apoptosis
C	1900119	biological_process	positive regulation of execution phase of apoptosis
D	0000166	molecular_function	nucleotide binding
D	0001530	molecular_function	lipopolysaccharide binding
D	0001819	biological_process	positive regulation of cytokine production
D	0002039	molecular_function	p53 binding
D	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
D	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
D	0003688	molecular_function	DNA replication origin binding
D	0003697	molecular_function	single-stranded DNA binding
D	0003723	molecular_function	RNA binding
D	0003725	molecular_function	double-stranded RNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005615	cellular_component	extracellular space
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005759	cellular_component	mitochondrial matrix
D	0005769	cellular_component	early endosome
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0005905	cellular_component	clathrin-coated pit
D	0006457	biological_process	protein folding
D	0006458	biological_process	'de novo' protein folding
D	0006986	biological_process	response to unfolded protein
D	0008035	molecular_function	high-density lipoprotein particle binding
D	0008637	biological_process	apoptotic mitochondrial changes
D	0009409	biological_process	response to cold
D	0009986	cellular_component	cell surface
D	0016020	cellular_component	membrane
D	0016853	molecular_function	isomerase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0019899	molecular_function	enzyme binding
D	0030135	cellular_component	coated vesicle
D	0030141	cellular_component	secretory granule
D	0031625	molecular_function	ubiquitin protein ligase binding
D	0032727	biological_process	positive regulation of interferon-alpha production
D	0032729	biological_process	positive regulation of type II interferon production
D	0032733	biological_process	positive regulation of interleukin-10 production
D	0032735	biological_process	positive regulation of interleukin-12 production
D	0032755	biological_process	positive regulation of interleukin-6 production
D	0032991	cellular_component	protein-containing complex
D	0034185	molecular_function	apolipoprotein binding
D	0034186	molecular_function	apolipoprotein A-I binding
D	0034514	biological_process	mitochondrial unfolded protein response
D	0042026	biological_process	protein refolding
D	0042100	biological_process	B cell proliferation
D	0042110	biological_process	T cell activation
D	0042113	biological_process	B cell activation
D	0043032	biological_process	positive regulation of macrophage activation
D	0043066	biological_process	negative regulation of apoptotic process
D	0044406	biological_process	adhesion of symbiont to host
D	0045041	biological_process	protein import into mitochondrial intermembrane space
D	0046696	cellular_component	lipopolysaccharide receptor complex
D	0048291	biological_process	isotype switching to IgG isotypes
D	0050821	biological_process	protein stabilization
D	0050870	biological_process	positive regulation of T cell activation
D	0051082	molecular_function	unfolded protein binding
D	0051087	molecular_function	protein-folding chaperone binding
D	0051131	biological_process	chaperone-mediated protein complex assembly
D	0051604	biological_process	protein maturation
D	0051702	biological_process	biological process involved in interaction with symbiont
D	0070062	cellular_component	extracellular exosome
D	0097225	cellular_component	sperm midpiece
D	0140494	cellular_component	migrasome
D	0140608	molecular_function	cysteine-type endopeptidase activator activity
D	1900118	biological_process	negative regulation of execution phase of apoptosis
D	1900119	biological_process	positive regulation of execution phase of apoptosis
E	0000166	molecular_function	nucleotide binding
E	0001530	molecular_function	lipopolysaccharide binding
E	0001819	biological_process	positive regulation of cytokine production
E	0002039	molecular_function	p53 binding
E	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
E	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
E	0003688	molecular_function	DNA replication origin binding
E	0003697	molecular_function	single-stranded DNA binding
E	0003723	molecular_function	RNA binding
E	0003725	molecular_function	double-stranded RNA binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005615	cellular_component	extracellular space
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005759	cellular_component	mitochondrial matrix
E	0005769	cellular_component	early endosome
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0005905	cellular_component	clathrin-coated pit
E	0006457	biological_process	protein folding
E	0006458	biological_process	'de novo' protein folding
E	0006986	biological_process	response to unfolded protein
E	0008035	molecular_function	high-density lipoprotein particle binding
E	0008637	biological_process	apoptotic mitochondrial changes
E	0009409	biological_process	response to cold
E	0009986	cellular_component	cell surface
E	0016020	cellular_component	membrane
E	0016853	molecular_function	isomerase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0019899	molecular_function	enzyme binding
E	0030135	cellular_component	coated vesicle
E	0030141	cellular_component	secretory granule
E	0031625	molecular_function	ubiquitin protein ligase binding
E	0032727	biological_process	positive regulation of interferon-alpha production
E	0032729	biological_process	positive regulation of type II interferon production
E	0032733	biological_process	positive regulation of interleukin-10 production
E	0032735	biological_process	positive regulation of interleukin-12 production
E	0032755	biological_process	positive regulation of interleukin-6 production
E	0032991	cellular_component	protein-containing complex
E	0034185	molecular_function	apolipoprotein binding
E	0034186	molecular_function	apolipoprotein A-I binding
E	0034514	biological_process	mitochondrial unfolded protein response
E	0042026	biological_process	protein refolding
E	0042100	biological_process	B cell proliferation
E	0042110	biological_process	T cell activation
E	0042113	biological_process	B cell activation
E	0043032	biological_process	positive regulation of macrophage activation
E	0043066	biological_process	negative regulation of apoptotic process
E	0044406	biological_process	adhesion of symbiont to host
E	0045041	biological_process	protein import into mitochondrial intermembrane space
E	0046696	cellular_component	lipopolysaccharide receptor complex
E	0048291	biological_process	isotype switching to IgG isotypes
E	0050821	biological_process	protein stabilization
E	0050870	biological_process	positive regulation of T cell activation
E	0051082	molecular_function	unfolded protein binding
E	0051087	molecular_function	protein-folding chaperone binding
E	0051131	biological_process	chaperone-mediated protein complex assembly
E	0051604	biological_process	protein maturation
E	0051702	biological_process	biological process involved in interaction with symbiont
E	0070062	cellular_component	extracellular exosome
E	0097225	cellular_component	sperm midpiece
E	0140494	cellular_component	migrasome
E	0140608	molecular_function	cysteine-type endopeptidase activator activity
E	1900118	biological_process	negative regulation of execution phase of apoptosis
E	1900119	biological_process	positive regulation of execution phase of apoptosis
F	0000166	molecular_function	nucleotide binding
F	0001530	molecular_function	lipopolysaccharide binding
F	0001819	biological_process	positive regulation of cytokine production
F	0002039	molecular_function	p53 binding
F	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
F	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
F	0003688	molecular_function	DNA replication origin binding
F	0003697	molecular_function	single-stranded DNA binding
F	0003723	molecular_function	RNA binding
F	0003725	molecular_function	double-stranded RNA binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005615	cellular_component	extracellular space
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005759	cellular_component	mitochondrial matrix
F	0005769	cellular_component	early endosome
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0005905	cellular_component	clathrin-coated pit
F	0006457	biological_process	protein folding
F	0006458	biological_process	'de novo' protein folding
F	0006986	biological_process	response to unfolded protein
F	0008035	molecular_function	high-density lipoprotein particle binding
F	0008637	biological_process	apoptotic mitochondrial changes
F	0009409	biological_process	response to cold
F	0009986	cellular_component	cell surface
F	0016020	cellular_component	membrane
F	0016853	molecular_function	isomerase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0019899	molecular_function	enzyme binding
F	0030135	cellular_component	coated vesicle
F	0030141	cellular_component	secretory granule
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032727	biological_process	positive regulation of interferon-alpha production
F	0032729	biological_process	positive regulation of type II interferon production
F	0032733	biological_process	positive regulation of interleukin-10 production
F	0032735	biological_process	positive regulation of interleukin-12 production
F	0032755	biological_process	positive regulation of interleukin-6 production
F	0032991	cellular_component	protein-containing complex
F	0034185	molecular_function	apolipoprotein binding
F	0034186	molecular_function	apolipoprotein A-I binding
F	0034514	biological_process	mitochondrial unfolded protein response
F	0042026	biological_process	protein refolding
F	0042100	biological_process	B cell proliferation
F	0042110	biological_process	T cell activation
F	0042113	biological_process	B cell activation
F	0043032	biological_process	positive regulation of macrophage activation
F	0043066	biological_process	negative regulation of apoptotic process
F	0044406	biological_process	adhesion of symbiont to host
F	0045041	biological_process	protein import into mitochondrial intermembrane space
F	0046696	cellular_component	lipopolysaccharide receptor complex
F	0048291	biological_process	isotype switching to IgG isotypes
F	0050821	biological_process	protein stabilization
F	0050870	biological_process	positive regulation of T cell activation
F	0051082	molecular_function	unfolded protein binding
F	0051087	molecular_function	protein-folding chaperone binding
F	0051131	biological_process	chaperone-mediated protein complex assembly
F	0051604	biological_process	protein maturation
F	0051702	biological_process	biological process involved in interaction with symbiont
F	0070062	cellular_component	extracellular exosome
F	0097225	cellular_component	sperm midpiece
F	0140494	cellular_component	migrasome
F	0140608	molecular_function	cysteine-type endopeptidase activator activity
F	1900118	biological_process	negative regulation of execution phase of apoptosis
F	1900119	biological_process	positive regulation of execution phase of apoptosis
G	0000166	molecular_function	nucleotide binding
G	0001530	molecular_function	lipopolysaccharide binding
G	0001819	biological_process	positive regulation of cytokine production
G	0002039	molecular_function	p53 binding
G	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
G	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
G	0003688	molecular_function	DNA replication origin binding
G	0003697	molecular_function	single-stranded DNA binding
G	0003723	molecular_function	RNA binding
G	0003725	molecular_function	double-stranded RNA binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005615	cellular_component	extracellular space
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005759	cellular_component	mitochondrial matrix
G	0005769	cellular_component	early endosome
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0005905	cellular_component	clathrin-coated pit
G	0006457	biological_process	protein folding
G	0006458	biological_process	'de novo' protein folding
G	0006986	biological_process	response to unfolded protein
G	0008035	molecular_function	high-density lipoprotein particle binding
G	0008637	biological_process	apoptotic mitochondrial changes
G	0009409	biological_process	response to cold
G	0009986	cellular_component	cell surface
G	0016020	cellular_component	membrane
G	0016853	molecular_function	isomerase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0019899	molecular_function	enzyme binding
G	0030135	cellular_component	coated vesicle
G	0030141	cellular_component	secretory granule
G	0031625	molecular_function	ubiquitin protein ligase binding
G	0032727	biological_process	positive regulation of interferon-alpha production
G	0032729	biological_process	positive regulation of type II interferon production
G	0032733	biological_process	positive regulation of interleukin-10 production
G	0032735	biological_process	positive regulation of interleukin-12 production
G	0032755	biological_process	positive regulation of interleukin-6 production
G	0032991	cellular_component	protein-containing complex
G	0034185	molecular_function	apolipoprotein binding
G	0034186	molecular_function	apolipoprotein A-I binding
G	0034514	biological_process	mitochondrial unfolded protein response
G	0042026	biological_process	protein refolding
G	0042100	biological_process	B cell proliferation
G	0042110	biological_process	T cell activation
G	0042113	biological_process	B cell activation
G	0043032	biological_process	positive regulation of macrophage activation
G	0043066	biological_process	negative regulation of apoptotic process
G	0044406	biological_process	adhesion of symbiont to host
G	0045041	biological_process	protein import into mitochondrial intermembrane space
G	0046696	cellular_component	lipopolysaccharide receptor complex
G	0048291	biological_process	isotype switching to IgG isotypes
G	0050821	biological_process	protein stabilization
G	0050870	biological_process	positive regulation of T cell activation
G	0051082	molecular_function	unfolded protein binding
G	0051087	molecular_function	protein-folding chaperone binding
G	0051131	biological_process	chaperone-mediated protein complex assembly
G	0051604	biological_process	protein maturation
G	0051702	biological_process	biological process involved in interaction with symbiont
G	0070062	cellular_component	extracellular exosome
G	0097225	cellular_component	sperm midpiece
G	0140494	cellular_component	migrasome
G	0140608	molecular_function	cysteine-type endopeptidase activator activity
G	1900118	biological_process	negative regulation of execution phase of apoptosis
G	1900119	biological_process	positive regulation of execution phase of apoptosis
a	0001649	biological_process	osteoblast differentiation
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005739	cellular_component	mitochondrion
a	0005759	cellular_component	mitochondrial matrix
a	0006457	biological_process	protein folding
a	0006986	biological_process	response to unfolded protein
a	0016020	cellular_component	membrane
a	0046872	molecular_function	metal ion binding
a	0051082	molecular_function	unfolded protein binding
a	0051087	molecular_function	protein-folding chaperone binding
a	0070062	cellular_component	extracellular exosome
a	0097193	biological_process	intrinsic apoptotic signaling pathway
b	0001649	biological_process	osteoblast differentiation
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005739	cellular_component	mitochondrion
b	0005759	cellular_component	mitochondrial matrix
b	0006457	biological_process	protein folding
b	0006986	biological_process	response to unfolded protein
b	0016020	cellular_component	membrane
b	0046872	molecular_function	metal ion binding
b	0051082	molecular_function	unfolded protein binding
b	0051087	molecular_function	protein-folding chaperone binding
b	0070062	cellular_component	extracellular exosome
b	0097193	biological_process	intrinsic apoptotic signaling pathway
c	0001649	biological_process	osteoblast differentiation
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005739	cellular_component	mitochondrion
c	0005759	cellular_component	mitochondrial matrix
c	0006457	biological_process	protein folding
c	0006986	biological_process	response to unfolded protein
c	0016020	cellular_component	membrane
c	0046872	molecular_function	metal ion binding
c	0051082	molecular_function	unfolded protein binding
c	0051087	molecular_function	protein-folding chaperone binding
c	0070062	cellular_component	extracellular exosome
c	0097193	biological_process	intrinsic apoptotic signaling pathway
d	0001649	biological_process	osteoblast differentiation
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005739	cellular_component	mitochondrion
d	0005759	cellular_component	mitochondrial matrix
d	0006457	biological_process	protein folding
d	0006986	biological_process	response to unfolded protein
d	0016020	cellular_component	membrane
d	0046872	molecular_function	metal ion binding
d	0051082	molecular_function	unfolded protein binding
d	0051087	molecular_function	protein-folding chaperone binding
d	0070062	cellular_component	extracellular exosome
d	0097193	biological_process	intrinsic apoptotic signaling pathway
e	0001649	biological_process	osteoblast differentiation
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005739	cellular_component	mitochondrion
e	0005759	cellular_component	mitochondrial matrix
e	0006457	biological_process	protein folding
e	0006986	biological_process	response to unfolded protein
e	0016020	cellular_component	membrane
e	0046872	molecular_function	metal ion binding
e	0051082	molecular_function	unfolded protein binding
e	0051087	molecular_function	protein-folding chaperone binding
e	0070062	cellular_component	extracellular exosome
e	0097193	biological_process	intrinsic apoptotic signaling pathway
f	0001649	biological_process	osteoblast differentiation
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005739	cellular_component	mitochondrion
f	0005759	cellular_component	mitochondrial matrix
f	0006457	biological_process	protein folding
f	0006986	biological_process	response to unfolded protein
f	0016020	cellular_component	membrane
f	0046872	molecular_function	metal ion binding
f	0051082	molecular_function	unfolded protein binding
f	0051087	molecular_function	protein-folding chaperone binding
f	0070062	cellular_component	extracellular exosome
f	0097193	biological_process	intrinsic apoptotic signaling pathway
g	0001649	biological_process	osteoblast differentiation
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005739	cellular_component	mitochondrion
g	0005759	cellular_component	mitochondrial matrix
g	0006457	biological_process	protein folding
g	0006986	biological_process	response to unfolded protein
g	0016020	cellular_component	membrane
g	0046872	molecular_function	metal ion binding
g	0051082	molecular_function	unfolded protein binding
g	0051087	molecular_function	protein-folding chaperone binding
g	0070062	cellular_component	extracellular exosome
g	0097193	biological_process	intrinsic apoptotic signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGIVlGGG

Chain	Residue	Details
A	ALA406-GLY417

---

site_id	PS00681
Number of Residues	25
Details	CHAPERONINS_CPN10 Chaperonins cpn10 signature. FlPLfDRVLVErsaaetvtkGgIML

Chain	Residue	Details
a	PHE9-LEU33

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	49
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25918392","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4PJ1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P63038","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	56
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P63038","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	84
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P63038","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	7
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	35
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	7
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P63038","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	7
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	14
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	7
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q64433","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	7
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q64433","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	49
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q64433","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	7
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---