9H5M

Cryo-EM structure of Gasdermin-E

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0012501	biological_process	programmed cell death
A	0012501	biological_process	programmed cell death
b	0012501	biological_process	programmed cell death
B	0012501	biological_process	programmed cell death
c	0012501	biological_process	programmed cell death
C	0012501	biological_process	programmed cell death
d	0012501	biological_process	programmed cell death
D	0012501	biological_process	programmed cell death
E	0012501	biological_process	programmed cell death
F	0012501	biological_process	programmed cell death
G	0012501	biological_process	programmed cell death
H	0012501	biological_process	programmed cell death
I	0012501	biological_process	programmed cell death
J	0012501	biological_process	programmed cell death
K	0012501	biological_process	programmed cell death
L	0012501	biological_process	programmed cell death
M	0012501	biological_process	programmed cell death
N	0012501	biological_process	programmed cell death
O	0012501	biological_process	programmed cell death
P	0012501	biological_process	programmed cell death
Q	0012501	biological_process	programmed cell death
R	0012501	biological_process	programmed cell death
S	0012501	biological_process	programmed cell death
T	0012501	biological_process	programmed cell death
U	0012501	biological_process	programmed cell death
V	0012501	biological_process	programmed cell death
W	0012501	biological_process	programmed cell death
X	0012501	biological_process	programmed cell death
Y	0012501	biological_process	programmed cell death
Z	0012501	biological_process	programmed cell death

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1650
Details	Region: {"description":"Membrane targeting domain","evidences":[{"source":"PubMed","id":"28045099","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	150
Details	Modified residue: {"description":"S-(2-succinyl)cysteine","evidences":[{"source":"PubMed","id":"32820063","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	90
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36607699","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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