9H0M

Structure of avian Pit54 SRCR 1-2 in complex with hemoglobin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005344	molecular_function	oxygen carrier activity
A	0005506	molecular_function	iron ion binding
A	0005576	cellular_component	extracellular region
A	0005833	cellular_component	hemoglobin complex
A	0015671	biological_process	oxygen transport
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0031838	cellular_component	haptoglobin-hemoglobin complex
A	0048821	biological_process	erythrocyte development
B	0005344	molecular_function	oxygen carrier activity
B	0005576	cellular_component	extracellular region
B	0005623	cellular_component	obsolete cell
B	0005833	cellular_component	hemoglobin complex
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0030492	molecular_function	hemoglobin binding
B	0031838	cellular_component	haptoglobin-hemoglobin complex
B	0048821	biological_process	erythrocyte development
C	0005344	molecular_function	oxygen carrier activity
C	0005506	molecular_function	iron ion binding
C	0005576	cellular_component	extracellular region
C	0005833	cellular_component	hemoglobin complex
C	0015671	biological_process	oxygen transport
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
C	0031838	cellular_component	haptoglobin-hemoglobin complex
C	0048821	biological_process	erythrocyte development
D	0005344	molecular_function	oxygen carrier activity
D	0005576	cellular_component	extracellular region
D	0005623	cellular_component	obsolete cell
D	0005833	cellular_component	hemoglobin complex
D	0015671	biological_process	oxygen transport
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
D	0030492	molecular_function	hemoglobin binding
D	0031838	cellular_component	haptoglobin-hemoglobin complex
D	0048821	biological_process	erythrocyte development
E	0005044	molecular_function	scavenger receptor activity
E	0005576	cellular_component	extracellular region
E	0006952	biological_process	defense response
E	0016020	cellular_component	membrane
E	0016192	biological_process	vesicle-mediated transport
E	0031012	cellular_component	extracellular matrix
E	0042494	biological_process	detection of bacterial lipoprotein
F	0005044	molecular_function	scavenger receptor activity
F	0005576	cellular_component	extracellular region
F	0006952	biological_process	defense response
F	0016020	cellular_component	membrane
F	0016192	biological_process	vesicle-mediated transport
F	0031012	cellular_component	extracellular matrix
F	0042494	biological_process	detection of bacterial lipoprotein
G	0005344	molecular_function	oxygen carrier activity
G	0005506	molecular_function	iron ion binding
G	0005576	cellular_component	extracellular region
G	0005833	cellular_component	hemoglobin complex
G	0015671	biological_process	oxygen transport
G	0019825	molecular_function	oxygen binding
G	0020037	molecular_function	heme binding
G	0031838	cellular_component	haptoglobin-hemoglobin complex
G	0048821	biological_process	erythrocyte development
H	0005344	molecular_function	oxygen carrier activity
H	0005576	cellular_component	extracellular region
H	0005623	cellular_component	obsolete cell
H	0005833	cellular_component	hemoglobin complex
H	0015671	biological_process	oxygen transport
H	0019825	molecular_function	oxygen binding
H	0020037	molecular_function	heme binding
H	0030492	molecular_function	hemoglobin binding
H	0031838	cellular_component	haptoglobin-hemoglobin complex
H	0048821	biological_process	erythrocyte development
I	0005344	molecular_function	oxygen carrier activity
I	0005506	molecular_function	iron ion binding
I	0005576	cellular_component	extracellular region
I	0005833	cellular_component	hemoglobin complex
I	0015671	biological_process	oxygen transport
I	0019825	molecular_function	oxygen binding
I	0020037	molecular_function	heme binding
I	0031838	cellular_component	haptoglobin-hemoglobin complex
I	0048821	biological_process	erythrocyte development
J	0005344	molecular_function	oxygen carrier activity
J	0005576	cellular_component	extracellular region
J	0005623	cellular_component	obsolete cell
J	0005833	cellular_component	hemoglobin complex
J	0015671	biological_process	oxygen transport
J	0019825	molecular_function	oxygen binding
J	0020037	molecular_function	heme binding
J	0030492	molecular_function	hemoglobin binding
J	0031838	cellular_component	haptoglobin-hemoglobin complex
J	0048821	biological_process	erythrocyte development
K	0005044	molecular_function	scavenger receptor activity
K	0005576	cellular_component	extracellular region
K	0006952	biological_process	defense response
K	0016020	cellular_component	membrane
K	0016192	biological_process	vesicle-mediated transport
K	0031012	cellular_component	extracellular matrix
K	0042494	biological_process	detection of bacterial lipoprotein
L	0005044	molecular_function	scavenger receptor activity
L	0005576	cellular_component	extracellular region
L	0006952	biological_process	defense response
L	0016020	cellular_component	membrane
L	0016192	biological_process	vesicle-mediated transport
L	0031012	cellular_component	extracellular matrix
L	0042494	biological_process	detection of bacterial lipoprotein

Functional Information from PROSITE/UniProt

site_id	PS00420
Number of Residues	38
Details	SRCR_1 SRCR domain signature. GpnrcsGrvEvlhndvWGtvCdegWdlrearvvCrqlG

Chain	Residue	Details
E	GLY72-GLY109
E	GLY182-GLY219
E	GLY292-GLY329
E	GLY402-GLY439

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	568
Details	Domain: {"description":"Globin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"description":"distal binding residue"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"description":"proximal binding residue"}

Chain

Residue

Details

---