9GUA
NCS-1 bound to FDA ligand 5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0005245 | molecular_function | voltage-gated calcium channel activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008048 | molecular_function | calcium sensitive guanylate cyclase activator activity |
| B | 0009966 | biological_process | regulation of signal transduction |
| B | 0010975 | biological_process | regulation of neuron projection development |
| B | 0014069 | cellular_component | postsynaptic density |
| B | 0016020 | cellular_component | membrane |
| B | 0030424 | cellular_component | axon |
| B | 0030425 | cellular_component | dendrite |
| B | 0048471 | cellular_component | perinuclear region of cytoplasm |
| B | 0070588 | biological_process | calcium ion transmembrane transport |
| D | 0005245 | molecular_function | voltage-gated calcium channel activity |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005794 | cellular_component | Golgi apparatus |
| D | 0005829 | cellular_component | cytosol |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0008048 | molecular_function | calcium sensitive guanylate cyclase activator activity |
| D | 0009966 | biological_process | regulation of signal transduction |
| D | 0010975 | biological_process | regulation of neuron projection development |
| D | 0014069 | cellular_component | postsynaptic density |
| D | 0016020 | cellular_component | membrane |
| D | 0030424 | cellular_component | axon |
| D | 0030425 | cellular_component | dendrite |
| D | 0048471 | cellular_component | perinuclear region of cytoplasm |
| D | 0070588 | biological_process | calcium ion transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DENKDGRIEfsEF |
| Chain | Residue | Details |
| B | ASP73-PHE85 | |
| B | ASP109-MET121 | |
| B | ASP157-PHE169 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 70 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 70 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 70 |
| Details | Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 70 |
| Details | Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 32 |
| Details | Region: {"description":"Interaction with IL1RAPL1","evidences":[{"source":"PubMed","id":"12783849","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P62168","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
