9GS7
Cryo-EM structure of human SLC35B1-E33A variant with AMP-PNP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0005459 | molecular_function | UDP-galactose transmembrane transporter activity |
| A | 0005460 | molecular_function | UDP-glucose transmembrane transporter activity |
| A | 0005471 | molecular_function | ATP:ADP antiporter activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0015297 | molecular_function | antiporter activity |
| A | 0015786 | biological_process | UDP-glucose transmembrane transport |
| A | 0015866 | biological_process | ADP transport |
| A | 0015867 | biological_process | ATP transport |
| A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0072334 | biological_process | UDP-galactose transmembrane transport |
| B | 0008643 | biological_process | carbohydrate transport |
| B | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS01037 |
| Number of Residues | 18 |
| Details | SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN |
| Chain | Residue | Details |
| B | PRO221-ASN238 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 39 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 37 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 15 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 17 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GRY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9GSL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"40399679","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9I20","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
