9GKI

Structure of 5mer pore intermediate of Sticholysin II (StnII) toxin in lipid nanodiscs

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006811	biological_process	monoatomic ion transport
A	0031640	biological_process	killing of cells of another organism
A	0035821	biological_process	modulation of process of another organism
A	0042151	cellular_component	nematocyst
A	0042802	molecular_function	identical protein binding
A	0044218	cellular_component	other organism cell membrane
A	0055085	biological_process	transmembrane transport
A	0090729	molecular_function	toxin activity
B	0005576	cellular_component	extracellular region
B	0006811	biological_process	monoatomic ion transport
B	0031640	biological_process	killing of cells of another organism
B	0035821	biological_process	modulation of process of another organism
B	0042151	cellular_component	nematocyst
B	0042802	molecular_function	identical protein binding
B	0044218	cellular_component	other organism cell membrane
B	0055085	biological_process	transmembrane transport
B	0090729	molecular_function	toxin activity
f	0005576	cellular_component	extracellular region
f	0006811	biological_process	monoatomic ion transport
f	0031640	biological_process	killing of cells of another organism
f	0035821	biological_process	modulation of process of another organism
f	0042151	cellular_component	nematocyst
f	0042802	molecular_function	identical protein binding
f	0044218	cellular_component	other organism cell membrane
f	0055085	biological_process	transmembrane transport
f	0090729	molecular_function	toxin activity
n	0005576	cellular_component	extracellular region
n	0006811	biological_process	monoatomic ion transport
n	0031640	biological_process	killing of cells of another organism
n	0035821	biological_process	modulation of process of another organism
n	0042151	cellular_component	nematocyst
n	0042802	molecular_function	identical protein binding
n	0044218	cellular_component	other organism cell membrane
n	0055085	biological_process	transmembrane transport
n	0090729	molecular_function	toxin activity
v	0005576	cellular_component	extracellular region
v	0006811	biological_process	monoatomic ion transport
v	0031640	biological_process	killing of cells of another organism
v	0035821	biological_process	modulation of process of another organism
v	0042151	cellular_component	nematocyst
v	0042802	molecular_function	identical protein binding
v	0044218	cellular_component	other organism cell membrane
v	0055085	biological_process	transmembrane transport
v	0090729	molecular_function	toxin activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	75
Details	Region: {"description":"Trp-rich region, which is important for the binding to lipid membrane","evidences":[{"source":"UniProtKB","id":"P61914","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Motif: {"description":"Cell attachment site, crucial for protein stability","evidences":[{"source":"PubMed","id":"24418371","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	35
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14604522","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	Site: {"description":"Important in the initial contact with the lipid membrane","evidences":[{"source":"UniProtKB","id":"P61914","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	9
Details	Region: {"description":"Plays an important role in the hemolytic activity","evidences":[{"source":"PubMed","id":"16170802","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	19
Details	Region: {"description":"N-terminal region","evidences":[{"source":"UniProtKB","id":"P61914","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---