9GIU
Cryo-EM structure of human SLC45A4 in detergent
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000297 | molecular_function | spermine transmembrane transporter activity |
| A | 0005351 | molecular_function | carbohydrate:proton symporter activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008506 | molecular_function | sucrose:proton symporter activity |
| A | 0015203 | molecular_function | polyamine transmembrane transporter activity |
| A | 0015489 | molecular_function | putrescine transmembrane transporter activity |
| A | 0015606 | molecular_function | spermidine transmembrane transporter activity |
| A | 0015770 | biological_process | sucrose transport |
| A | 0015847 | biological_process | putrescine transport |
| A | 0016020 | cellular_component | membrane |
| A | 0019233 | biological_process | sensory perception of pain |
| A | 0034219 | biological_process | carbohydrate transmembrane transport |
| A | 1902047 | biological_process | polyamine transmembrane transport |
| A | 1902600 | biological_process | proton transmembrane transport |
| A | 1903710 | biological_process | spermine transmembrane transport |
| A | 1903711 | biological_process | spermidine transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 34 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 25 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 26 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 31 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 30 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 41 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 34 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 35 |
| Details | Transmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 29 |
| Details | Transmembrane: {"description":"Helical; Name=11","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=12","evidences":[{"source":"PubMed","id":"40836097","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9GIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
