Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9GI1

Structure of the S.aureus MecA/ClpC/ClpP degradation system

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0005524	molecular_function	ATP binding
a	0006457	biological_process	protein folding
a	0016887	molecular_function	ATP hydrolysis activity
a	0044183	molecular_function	protein folding chaperone
a	1990169	biological_process	stress response to copper ion
a	1990170	biological_process	stress response to cadmium ion
b	0005524	molecular_function	ATP binding
b	0006457	biological_process	protein folding
b	0016887	molecular_function	ATP hydrolysis activity
b	0044183	molecular_function	protein folding chaperone
b	1990169	biological_process	stress response to copper ion
b	1990170	biological_process	stress response to cadmium ion
c	0005524	molecular_function	ATP binding
c	0006457	biological_process	protein folding
c	0016887	molecular_function	ATP hydrolysis activity
c	0044183	molecular_function	protein folding chaperone
c	1990169	biological_process	stress response to copper ion
c	1990170	biological_process	stress response to cadmium ion
d	0005524	molecular_function	ATP binding
d	0006457	biological_process	protein folding
d	0016887	molecular_function	ATP hydrolysis activity
d	0044183	molecular_function	protein folding chaperone
d	1990169	biological_process	stress response to copper ion
d	1990170	biological_process	stress response to cadmium ion
e	0005524	molecular_function	ATP binding
e	0006457	biological_process	protein folding
e	0016887	molecular_function	ATP hydrolysis activity
e	0044183	molecular_function	protein folding chaperone
e	1990169	biological_process	stress response to copper ion
e	1990170	biological_process	stress response to cadmium ion
f	0005524	molecular_function	ATP binding
f	0006457	biological_process	protein folding
f	0016887	molecular_function	ATP hydrolysis activity
f	0044183	molecular_function	protein folding chaperone
f	1990169	biological_process	stress response to copper ion
f	1990170	biological_process	stress response to cadmium ion
Pa	0004176	molecular_function	ATP-dependent peptidase activity
Pa	0004252	molecular_function	serine-type endopeptidase activity
Pa	0005737	cellular_component	cytoplasm
Pa	0006508	biological_process	proteolysis
Pa	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pa	0042802	molecular_function	identical protein binding
Pa	0051117	molecular_function	ATPase binding
Pb	0004176	molecular_function	ATP-dependent peptidase activity
Pb	0004252	molecular_function	serine-type endopeptidase activity
Pb	0005737	cellular_component	cytoplasm
Pb	0006508	biological_process	proteolysis
Pb	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pb	0042802	molecular_function	identical protein binding
Pb	0051117	molecular_function	ATPase binding
Pc	0004176	molecular_function	ATP-dependent peptidase activity
Pc	0004252	molecular_function	serine-type endopeptidase activity
Pc	0005737	cellular_component	cytoplasm
Pc	0006508	biological_process	proteolysis
Pc	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pc	0042802	molecular_function	identical protein binding
Pc	0051117	molecular_function	ATPase binding
Pd	0004176	molecular_function	ATP-dependent peptidase activity
Pd	0004252	molecular_function	serine-type endopeptidase activity
Pd	0005737	cellular_component	cytoplasm
Pd	0006508	biological_process	proteolysis
Pd	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pd	0042802	molecular_function	identical protein binding
Pd	0051117	molecular_function	ATPase binding
Pe	0004176	molecular_function	ATP-dependent peptidase activity
Pe	0004252	molecular_function	serine-type endopeptidase activity
Pe	0005737	cellular_component	cytoplasm
Pe	0006508	biological_process	proteolysis
Pe	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pe	0042802	molecular_function	identical protein binding
Pe	0051117	molecular_function	ATPase binding
Pf	0004176	molecular_function	ATP-dependent peptidase activity
Pf	0004252	molecular_function	serine-type endopeptidase activity
Pf	0005737	cellular_component	cytoplasm
Pf	0006508	biological_process	proteolysis
Pf	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pf	0042802	molecular_function	identical protein binding
Pf	0051117	molecular_function	ATPase binding
Pg	0004176	molecular_function	ATP-dependent peptidase activity
Pg	0004252	molecular_function	serine-type endopeptidase activity
Pg	0005737	cellular_component	cytoplasm
Pg	0006508	biological_process	proteolysis
Pg	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pg	0042802	molecular_function	identical protein binding
Pg	0051117	molecular_function	ATPase binding
Ph	0004176	molecular_function	ATP-dependent peptidase activity
Ph	0004252	molecular_function	serine-type endopeptidase activity
Ph	0005737	cellular_component	cytoplasm
Ph	0006508	biological_process	proteolysis
Ph	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Ph	0042802	molecular_function	identical protein binding
Ph	0051117	molecular_function	ATPase binding
Pi	0004176	molecular_function	ATP-dependent peptidase activity
Pi	0004252	molecular_function	serine-type endopeptidase activity
Pi	0005737	cellular_component	cytoplasm
Pi	0006508	biological_process	proteolysis
Pi	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pi	0042802	molecular_function	identical protein binding
Pi	0051117	molecular_function	ATPase binding
Pl	0004176	molecular_function	ATP-dependent peptidase activity
Pl	0004252	molecular_function	serine-type endopeptidase activity
Pl	0005737	cellular_component	cytoplasm
Pl	0006508	biological_process	proteolysis
Pl	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pl	0042802	molecular_function	identical protein binding
Pl	0051117	molecular_function	ATPase binding
Pm	0004176	molecular_function	ATP-dependent peptidase activity
Pm	0004252	molecular_function	serine-type endopeptidase activity
Pm	0005737	cellular_component	cytoplasm
Pm	0006508	biological_process	proteolysis
Pm	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pm	0042802	molecular_function	identical protein binding
Pm	0051117	molecular_function	ATPase binding
Pn	0004176	molecular_function	ATP-dependent peptidase activity
Pn	0004252	molecular_function	serine-type endopeptidase activity
Pn	0005737	cellular_component	cytoplasm
Pn	0006508	biological_process	proteolysis
Pn	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pn	0042802	molecular_function	identical protein binding
Pn	0051117	molecular_function	ATPase binding
Po	0004176	molecular_function	ATP-dependent peptidase activity
Po	0004252	molecular_function	serine-type endopeptidase activity
Po	0005737	cellular_component	cytoplasm
Po	0006508	biological_process	proteolysis
Po	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Po	0042802	molecular_function	identical protein binding
Po	0051117	molecular_function	ATPase binding
Pq	0004176	molecular_function	ATP-dependent peptidase activity
Pq	0004252	molecular_function	serine-type endopeptidase activity
Pq	0005737	cellular_component	cytoplasm
Pq	0006508	biological_process	proteolysis
Pq	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pq	0042802	molecular_function	identical protein binding
Pq	0051117	molecular_function	ATPase binding

Functional Information from PROSITE/UniProt

site_id	PS00381
Number of Residues	12
Details	CLP_PROTEASE_SER Endopeptidase Clp serine active site. TicIGmAASMGS

Chain	Residue	Details
Pa	THR90-SER101

site_id	PS00382
Number of Residues	14
Details	CLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RfalPnaeVMIHQP

Chain	Residue	Details
Pa	ARG112-PRO125

site_id	PS00870
Number of Residues	13
Details	CLPAB_1 Chaperonins clpA/B signature 1. DASNILKPaLarG

Chain	Residue	Details
a	ASP295-GLY307

site_id	PS00871
Number of Residues	19
Details	CLPAB_2 Chaperonins clpA/B signature 2. RVDmSEFmEKhAvSRLvGA

Chain	Residue	Details
a	ARG571-ALA589

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	14
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	84
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	764
Details	Region: {"description":"II"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)