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9GI1

Structure of the S.aureus MecA/ClpC/ClpP degradation system

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
Pa0004176molecular_functionATP-dependent peptidase activity
Pa0004252molecular_functionserine-type endopeptidase activity
Pa0005737cellular_componentcytoplasm
Pa0006508biological_processproteolysis
Pa0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pa0008233molecular_functionpeptidase activity
Pa0008236molecular_functionserine-type peptidase activity
Pa0009368cellular_componentendopeptidase Clp complex
Pa0016787molecular_functionhydrolase activity
Pa0042802molecular_functionidentical protein binding
Pa0051117molecular_functionATPase binding
Pb0004176molecular_functionATP-dependent peptidase activity
Pb0004252molecular_functionserine-type endopeptidase activity
Pb0005737cellular_componentcytoplasm
Pb0006508biological_processproteolysis
Pb0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pb0008233molecular_functionpeptidase activity
Pb0008236molecular_functionserine-type peptidase activity
Pb0009368cellular_componentendopeptidase Clp complex
Pb0016787molecular_functionhydrolase activity
Pb0042802molecular_functionidentical protein binding
Pb0051117molecular_functionATPase binding
Pc0004176molecular_functionATP-dependent peptidase activity
Pc0004252molecular_functionserine-type endopeptidase activity
Pc0005737cellular_componentcytoplasm
Pc0006508biological_processproteolysis
Pc0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pc0008233molecular_functionpeptidase activity
Pc0008236molecular_functionserine-type peptidase activity
Pc0009368cellular_componentendopeptidase Clp complex
Pc0016787molecular_functionhydrolase activity
Pc0042802molecular_functionidentical protein binding
Pc0051117molecular_functionATPase binding
Pd0004176molecular_functionATP-dependent peptidase activity
Pd0004252molecular_functionserine-type endopeptidase activity
Pd0005737cellular_componentcytoplasm
Pd0006508biological_processproteolysis
Pd0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pd0008233molecular_functionpeptidase activity
Pd0008236molecular_functionserine-type peptidase activity
Pd0009368cellular_componentendopeptidase Clp complex
Pd0016787molecular_functionhydrolase activity
Pd0042802molecular_functionidentical protein binding
Pd0051117molecular_functionATPase binding
Pe0004176molecular_functionATP-dependent peptidase activity
Pe0004252molecular_functionserine-type endopeptidase activity
Pe0005737cellular_componentcytoplasm
Pe0006508biological_processproteolysis
Pe0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pe0008233molecular_functionpeptidase activity
Pe0008236molecular_functionserine-type peptidase activity
Pe0009368cellular_componentendopeptidase Clp complex
Pe0016787molecular_functionhydrolase activity
Pe0042802molecular_functionidentical protein binding
Pe0051117molecular_functionATPase binding
Pf0004176molecular_functionATP-dependent peptidase activity
Pf0004252molecular_functionserine-type endopeptidase activity
Pf0005737cellular_componentcytoplasm
Pf0006508biological_processproteolysis
Pf0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pf0008233molecular_functionpeptidase activity
Pf0008236molecular_functionserine-type peptidase activity
Pf0009368cellular_componentendopeptidase Clp complex
Pf0016787molecular_functionhydrolase activity
Pf0042802molecular_functionidentical protein binding
Pf0051117molecular_functionATPase binding
Pg0004176molecular_functionATP-dependent peptidase activity
Pg0004252molecular_functionserine-type endopeptidase activity
Pg0005737cellular_componentcytoplasm
Pg0006508biological_processproteolysis
Pg0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pg0008233molecular_functionpeptidase activity
Pg0008236molecular_functionserine-type peptidase activity
Pg0009368cellular_componentendopeptidase Clp complex
Pg0016787molecular_functionhydrolase activity
Pg0042802molecular_functionidentical protein binding
Pg0051117molecular_functionATPase binding
Ph0004176molecular_functionATP-dependent peptidase activity
Ph0004252molecular_functionserine-type endopeptidase activity
Ph0005737cellular_componentcytoplasm
Ph0006508biological_processproteolysis
Ph0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Ph0008233molecular_functionpeptidase activity
Ph0008236molecular_functionserine-type peptidase activity
Ph0009368cellular_componentendopeptidase Clp complex
Ph0016787molecular_functionhydrolase activity
Ph0042802molecular_functionidentical protein binding
Ph0051117molecular_functionATPase binding
Pi0004176molecular_functionATP-dependent peptidase activity
Pi0004252molecular_functionserine-type endopeptidase activity
Pi0005737cellular_componentcytoplasm
Pi0006508biological_processproteolysis
Pi0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pi0008233molecular_functionpeptidase activity
Pi0008236molecular_functionserine-type peptidase activity
Pi0009368cellular_componentendopeptidase Clp complex
Pi0016787molecular_functionhydrolase activity
Pi0042802molecular_functionidentical protein binding
Pi0051117molecular_functionATPase binding
Pl0004176molecular_functionATP-dependent peptidase activity
Pl0004252molecular_functionserine-type endopeptidase activity
Pl0005737cellular_componentcytoplasm
Pl0006508biological_processproteolysis
Pl0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pl0008233molecular_functionpeptidase activity
Pl0008236molecular_functionserine-type peptidase activity
Pl0009368cellular_componentendopeptidase Clp complex
Pl0016787molecular_functionhydrolase activity
Pl0042802molecular_functionidentical protein binding
Pl0051117molecular_functionATPase binding
Pm0004176molecular_functionATP-dependent peptidase activity
Pm0004252molecular_functionserine-type endopeptidase activity
Pm0005737cellular_componentcytoplasm
Pm0006508biological_processproteolysis
Pm0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pm0008233molecular_functionpeptidase activity
Pm0008236molecular_functionserine-type peptidase activity
Pm0009368cellular_componentendopeptidase Clp complex
Pm0016787molecular_functionhydrolase activity
Pm0042802molecular_functionidentical protein binding
Pm0051117molecular_functionATPase binding
Pn0004176molecular_functionATP-dependent peptidase activity
Pn0004252molecular_functionserine-type endopeptidase activity
Pn0005737cellular_componentcytoplasm
Pn0006508biological_processproteolysis
Pn0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pn0008233molecular_functionpeptidase activity
Pn0008236molecular_functionserine-type peptidase activity
Pn0009368cellular_componentendopeptidase Clp complex
Pn0016787molecular_functionhydrolase activity
Pn0042802molecular_functionidentical protein binding
Pn0051117molecular_functionATPase binding
Po0004176molecular_functionATP-dependent peptidase activity
Po0004252molecular_functionserine-type endopeptidase activity
Po0005737cellular_componentcytoplasm
Po0006508biological_processproteolysis
Po0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Po0008233molecular_functionpeptidase activity
Po0008236molecular_functionserine-type peptidase activity
Po0009368cellular_componentendopeptidase Clp complex
Po0016787molecular_functionhydrolase activity
Po0042802molecular_functionidentical protein binding
Po0051117molecular_functionATPase binding
Pq0004176molecular_functionATP-dependent peptidase activity
Pq0004252molecular_functionserine-type endopeptidase activity
Pq0005737cellular_componentcytoplasm
Pq0006508biological_processproteolysis
Pq0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Pq0008233molecular_functionpeptidase activity
Pq0008236molecular_functionserine-type peptidase activity
Pq0009368cellular_componentendopeptidase Clp complex
Pq0016787molecular_functionhydrolase activity
Pq0042802molecular_functionidentical protein binding
Pq0051117molecular_functionATPase binding
a0000166molecular_functionnucleotide binding
a0005524molecular_functionATP binding
a0006457biological_processprotein folding
a0044183molecular_functionprotein folding chaperone
a1990169biological_processstress response to copper ion
a1990170biological_processstress response to cadmium ion
b0000166molecular_functionnucleotide binding
b0005524molecular_functionATP binding
b0006457biological_processprotein folding
b0044183molecular_functionprotein folding chaperone
b1990169biological_processstress response to copper ion
b1990170biological_processstress response to cadmium ion
c0000166molecular_functionnucleotide binding
c0005524molecular_functionATP binding
c0006457biological_processprotein folding
c0044183molecular_functionprotein folding chaperone
c1990169biological_processstress response to copper ion
c1990170biological_processstress response to cadmium ion
d0000166molecular_functionnucleotide binding
d0005524molecular_functionATP binding
d0006457biological_processprotein folding
d0044183molecular_functionprotein folding chaperone
d1990169biological_processstress response to copper ion
d1990170biological_processstress response to cadmium ion
e0000166molecular_functionnucleotide binding
e0005524molecular_functionATP binding
e0006457biological_processprotein folding
e0044183molecular_functionprotein folding chaperone
e1990169biological_processstress response to copper ion
e1990170biological_processstress response to cadmium ion
f0000166molecular_functionnucleotide binding
f0005524molecular_functionATP binding
f0006457biological_processprotein folding
f0044183molecular_functionprotein folding chaperone
f1990169biological_processstress response to copper ion
f1990170biological_processstress response to cadmium ion
Functional Information from PROSITE/UniProt
site_idPS00381
Number of Residues12
DetailsCLP_PROTEASE_SER Endopeptidase Clp serine active site. TicIGmAASMGS
ChainResidueDetails
PaTHR90-SER101

site_idPS00382
Number of Residues14
DetailsCLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RfalPnaeVMIHQP
ChainResidueDetails
PaARG112-PRO125

site_idPS00870
Number of Residues13
DetailsCLPAB_1 Chaperonins clpA/B signature 1. DASNILKPaLarG
ChainResidueDetails
aASP295-GLY307

site_idPS00871
Number of Residues19
DetailsCLPAB_2 Chaperonins clpA/B signature 2. RVDmSEFmEKhAvSRLvGA
ChainResidueDetails
aARG571-ALA589

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsActive site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00444","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues14
DetailsActive site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00444","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues84
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues764
DetailsRegion: {"description":"II"}
ChainResidueDetails

247035

PDB entries from 2026-01-07

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