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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9G9Y

Respiratory supercomplex CI2-CIII2-CIV2 (megacomplex) from alphaproteobacterium

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
a0005886cellular_componentplasma membrane
a0008121molecular_functionquinol-cytochrome-c reductase activity
a0009055molecular_functionelectron transfer activity
a0016020cellular_componentmembrane
a0016491molecular_functionoxidoreductase activity
a0022900biological_processelectron transport chain
a0022904biological_processrespiratory electron transport chain
a0045275cellular_componentrespiratory chain complex III
a0046872molecular_functionmetal ion binding
a1902600biological_processproton transmembrane transport
A0005886cellular_componentplasma membrane
A0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
A0016020cellular_componentmembrane
A0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
A0030964cellular_componentNADH dehydrogenase complex
A0050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
A1902600biological_processproton transmembrane transport
A10005886cellular_componentplasma membrane
A10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
A10016020cellular_componentmembrane
A10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
A10030964cellular_componentNADH dehydrogenase complex
A10050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
A11902600biological_processproton transmembrane transport
b0009055molecular_functionelectron transfer activity
b0020037molecular_functionheme binding
B0005506molecular_functioniron ion binding
B0005886cellular_componentplasma membrane
B0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
B0009060biological_processaerobic respiration
B0015990biological_processelectron transport coupled proton transport
B0045271cellular_componentrespiratory chain complex I
B0048038molecular_functionquinone binding
B0050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
B0051536molecular_functioniron-sulfur cluster binding
B0051539molecular_function4 iron, 4 sulfur cluster binding
B10005506molecular_functioniron ion binding
B10005886cellular_componentplasma membrane
B10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
B10009060biological_processaerobic respiration
B10015990biological_processelectron transport coupled proton transport
B10045271cellular_componentrespiratory chain complex I
B10048038molecular_functionquinone binding
B10050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
B10051536molecular_functioniron-sulfur cluster binding
B10051539molecular_function4 iron, 4 sulfur cluster binding
c0005886cellular_componentplasma membrane
c0008121molecular_functionquinol-cytochrome-c reductase activity
c0016020cellular_componentmembrane
c0051537molecular_function2 iron, 2 sulfur cluster binding
c1902600biological_processproton transmembrane transport
C0005886cellular_componentplasma membrane
C0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
C0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
C0050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
C1902600biological_processproton transmembrane transport
C10005886cellular_componentplasma membrane
C10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
C10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
C10050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
C11902600biological_processproton transmembrane transport
d0005886cellular_componentplasma membrane
d0008121molecular_functionquinol-cytochrome-c reductase activity
d0009055molecular_functionelectron transfer activity
d0016020cellular_componentmembrane
d0016491molecular_functionoxidoreductase activity
d0022900biological_processelectron transport chain
d0022904biological_processrespiratory electron transport chain
d0045275cellular_componentrespiratory chain complex III
d0046872molecular_functionmetal ion binding
d1902600biological_processproton transmembrane transport
D0005886cellular_componentplasma membrane
D0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
D0048038molecular_functionquinone binding
D0050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
D0051287molecular_functionNAD binding
D10005886cellular_componentplasma membrane
D10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
D10048038molecular_functionquinone binding
D10050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
D10051287molecular_functionNAD binding
e0009055molecular_functionelectron transfer activity
e0020037molecular_functionheme binding
E0003954molecular_functionNADH dehydrogenase activity
E0005737cellular_componentcytoplasm
E0008324molecular_functionmonoatomic cation transmembrane transporter activity
E0016491molecular_functionoxidoreductase activity
E0022804molecular_functionactive transmembrane transporter activity
E0030964cellular_componentNADH dehydrogenase complex
E0031967cellular_componentorganelle envelope
E0055085biological_processtransmembrane transport
E0098655biological_processmonoatomic cation transmembrane transport
E10003954molecular_functionNADH dehydrogenase activity
E10005737cellular_componentcytoplasm
E10008324molecular_functionmonoatomic cation transmembrane transporter activity
E10016491molecular_functionoxidoreductase activity
E10022804molecular_functionactive transmembrane transporter activity
E10030964cellular_componentNADH dehydrogenase complex
E10031967cellular_componentorganelle envelope
E10055085biological_processtransmembrane transport
E10098655biological_processmonoatomic cation transmembrane transport
f0005886cellular_componentplasma membrane
f0008121molecular_functionquinol-cytochrome-c reductase activity
f0016020cellular_componentmembrane
f0051537molecular_function2 iron, 2 sulfur cluster binding
f1902600biological_processproton transmembrane transport
F0005737cellular_componentcytoplasm
F0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
F0010181molecular_functionFMN binding
F0016696molecular_functionoxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor
F0045271cellular_componentrespiratory chain complex I
F0051287molecular_functionNAD binding
F0051539molecular_function4 iron, 4 sulfur cluster binding
F1902600biological_processproton transmembrane transport
F10005737cellular_componentcytoplasm
F10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
F10010181molecular_functionFMN binding
F10016696molecular_functionoxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor
F10045271cellular_componentrespiratory chain complex I
F10051287molecular_functionNAD binding
F10051539molecular_function4 iron, 4 sulfur cluster binding
F11902600biological_processproton transmembrane transport
g0004129molecular_functioncytochrome-c oxidase activity
g0005886cellular_componentplasma membrane
g0006119biological_processoxidative phosphorylation
g0009060biological_processaerobic respiration
g0015990biological_processelectron transport coupled proton transport
g0016020cellular_componentmembrane
g0020037molecular_functionheme binding
g0022904biological_processrespiratory electron transport chain
g0045277cellular_componentrespiratory chain complex IV
G0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
G0009055molecular_functionelectron transfer activity
G0016020cellular_componentmembrane
G0016491molecular_functionoxidoreductase activity
G0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
G0042773biological_processATP synthesis coupled electron transport
G0051536molecular_functioniron-sulfur cluster binding
G1902600biological_processproton transmembrane transport
G10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
G10009055molecular_functionelectron transfer activity
G10016020cellular_componentmembrane
G10016491molecular_functionoxidoreductase activity
G10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
G10042773biological_processATP synthesis coupled electron transport
G10051536molecular_functioniron-sulfur cluster binding
G11902600biological_processproton transmembrane transport
h0004129molecular_functioncytochrome-c oxidase activity
h0005507molecular_functioncopper ion binding
h0016020cellular_componentmembrane
h0016491molecular_functionoxidoreductase activity
h0022900biological_processelectron transport chain
H0003954molecular_functionNADH dehydrogenase activity
H0005886cellular_componentplasma membrane
H0009060biological_processaerobic respiration
H0016020cellular_componentmembrane
H0016655molecular_functionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
H10003954molecular_functionNADH dehydrogenase activity
H10005886cellular_componentplasma membrane
H10009060biological_processaerobic respiration
H10016020cellular_componentmembrane
H10016655molecular_functionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
i0004129molecular_functioncytochrome-c oxidase activity
i0005886cellular_componentplasma membrane
i0009055molecular_functionelectron transfer activity
i0009060biological_processaerobic respiration
i0016020cellular_componentmembrane
i0019646biological_processaerobic electron transport chain
i0022904biological_processrespiratory electron transport chain
i1902600biological_processproton transmembrane transport
I0003954molecular_functionNADH dehydrogenase activity
I0005506molecular_functioniron ion binding
I0005737cellular_componentcytoplasm
I0005886cellular_componentplasma membrane
I0009060biological_processaerobic respiration
I0016020cellular_componentmembrane
I0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
I0050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
I0051539molecular_function4 iron, 4 sulfur cluster binding
I10003954molecular_functionNADH dehydrogenase activity
I10005506molecular_functioniron ion binding
I10005737cellular_componentcytoplasm
I10005886cellular_componentplasma membrane
I10009060biological_processaerobic respiration
I10016020cellular_componentmembrane
I10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
I10050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
I10051539molecular_function4 iron, 4 sulfur cluster binding
J0005886cellular_componentplasma membrane
J0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
J1902600biological_processproton transmembrane transport
J10005886cellular_componentplasma membrane
J10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
J11902600biological_processproton transmembrane transport
k0004129molecular_functioncytochrome-c oxidase activity
k0005886cellular_componentplasma membrane
k0006119biological_processoxidative phosphorylation
k0009060biological_processaerobic respiration
k0015990biological_processelectron transport coupled proton transport
k0016020cellular_componentmembrane
k0020037molecular_functionheme binding
k0022904biological_processrespiratory electron transport chain
k0045277cellular_componentrespiratory chain complex IV
K0005886cellular_componentplasma membrane
K0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
K0030964cellular_componentNADH dehydrogenase complex
K0042773biological_processATP synthesis coupled electron transport
K0050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
K10005886cellular_componentplasma membrane
K10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
K10030964cellular_componentNADH dehydrogenase complex
K10042773biological_processATP synthesis coupled electron transport
K10050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
l0004129molecular_functioncytochrome-c oxidase activity
l0005507molecular_functioncopper ion binding
l0016020cellular_componentmembrane
l0016491molecular_functionoxidoreductase activity
l0022900biological_processelectron transport chain
L0003954molecular_functionNADH dehydrogenase activity
L0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
L0015990biological_processelectron transport coupled proton transport
L0016020cellular_componentmembrane
L0042773biological_processATP synthesis coupled electron transport
L10003954molecular_functionNADH dehydrogenase activity
L10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
L10015990biological_processelectron transport coupled proton transport
L10016020cellular_componentmembrane
L10042773biological_processATP synthesis coupled electron transport
m0004129molecular_functioncytochrome-c oxidase activity
m0005886cellular_componentplasma membrane
m0009055molecular_functionelectron transfer activity
m0009060biological_processaerobic respiration
m0016020cellular_componentmembrane
m0019646biological_processaerobic electron transport chain
m0022904biological_processrespiratory electron transport chain
m1902600biological_processproton transmembrane transport
M0003954molecular_functionNADH dehydrogenase activity
M0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
M0009060biological_processaerobic respiration
M0015990biological_processelectron transport coupled proton transport
M0016020cellular_componentmembrane
M0042773biological_processATP synthesis coupled electron transport
M0048039molecular_functionubiquinone binding
M10003954molecular_functionNADH dehydrogenase activity
M10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
M10009060biological_processaerobic respiration
M10015990biological_processelectron transport coupled proton transport
M10016020cellular_componentmembrane
M10042773biological_processATP synthesis coupled electron transport
M10048039molecular_functionubiquinone binding
N0005886cellular_componentplasma membrane
N0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
N0042773biological_processATP synthesis coupled electron transport
N0050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
N1902600biological_processproton transmembrane transport
N10005886cellular_componentplasma membrane
N10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
N10042773biological_processATP synthesis coupled electron transport
N10050136molecular_functionNADH dehydrogenase (quinone) (non-electrogenic) activity
N11902600biological_processproton transmembrane transport
o0005886cellular_componentplasma membrane
o0009055molecular_functionelectron transfer activity
o0020037molecular_functionheme binding
p0005886cellular_componentplasma membrane
p0009055molecular_functionelectron transfer activity
p0020037molecular_functionheme binding
P0005737cellular_componentcytoplasm
P0044877molecular_functionprotein-containing complex binding
P10005737cellular_componentcytoplasm
P10044877molecular_functionprotein-containing complex binding
q0006979biological_processresponse to oxidative stress
q0016020cellular_componentmembrane
q0045271cellular_componentrespiratory chain complex I
Q0016020cellular_componentmembrane
Q0022900biological_processelectron transport chain
q10006979biological_processresponse to oxidative stress
q10016020cellular_componentmembrane
q10045271cellular_componentrespiratory chain complex I
Q10016020cellular_componentmembrane
Q10022900biological_processelectron transport chain
Z0004719molecular_functionprotein-L-isoaspartate (D-aspartate) O-methyltransferase activity
Z0005737cellular_componentcytoplasm
Z0036211biological_processprotein modification process
Z10004719molecular_functionprotein-L-isoaspartate (D-aspartate) O-methyltransferase activity
Z10005737cellular_componentcytoplasm
Z10036211biological_processprotein modification process
Functional Information from PROSITE/UniProt
site_idPS00036
Number of Residues15
DetailsBZIP_BASIC Basic-leucine zipper (bZIP) domain signature. Kpa.RNAmQSGTaRTR
ChainResidueDetails
QLYS7-ARG21
site_idPS00077
Number of Residues55
DetailsCOX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyiiilpgfgiishvistfakkpifgylpmvlamaaigilgfvvwa..HH
ChainResidueDetails
gTRP272-HIS326
site_idPS00078
Number of Residues49
DetailsCOX2 CO II and nitrous oxide reductase dinuclear copper centers signature. ViHawtipafavkqdavpgriaqlwfsvdqegvyfgq......CselCginHayM
ChainResidueDetails
hVAL208-MET256
site_idPS00198
Number of Residues12
Details4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP
ChainResidueDetails
ICYS64-PRO75
ICYS103-PRO114
site_idPS00535
Number of Residues12
DetailsCOMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLmEsR
ChainResidueDetails
DLEU63-ARG74
site_idPS00542
Number of Residues22
DetailsCOMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREvfDLFgilfsgHsdlRrIL
ChainResidueDetails
CGLU118-LEU139
site_idPS00641
Number of Residues18
DetailsCOMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsiaGnCRmC
ChainResidueDetails
GPRO34-CYS51
site_idPS00642
Number of Residues13
DetailsCOMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ
ChainResidueDetails
GCYS110-GLN122
site_idPS00643
Number of Residues11
DetailsCOMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIsCtRCVrF
ChainResidueDetails
GARG157-PHE167
site_idPS00644
Number of Residues16
DetailsCOMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALLES
ChainResidueDetails
FGLY167-SER182
site_idPS00645
Number of Residues12
DetailsCOMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG
ChainResidueDetails
FGLU344-GLY355
site_idPS00667
Number of Residues16
DetailsCOMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQtFaDALKYIvKE
ChainResidueDetails
HGLY57-GLU72
site_idPS00668
Number of Residues14
DetailsCOMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLVEAEseLVa.G
ChainResidueDetails
HPRO217-GLY230
site_idPS01099
Number of Residues19
DetailsCOMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DgrFSweeveCLGaCtnAP
ChainResidueDetails
EASP127-PRO145
site_idPS01150
Number of Residues17
DetailsCOMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP
ChainResidueDetails
BGLY135-PRO151
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI2
Number of Residues8
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01356","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues324
DetailsTransmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_01350","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues60
DetailsDomain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"HAMAP-Rule","id":"MF_01351","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues58
DetailsDomain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"HAMAP-Rule","id":"MF_01351","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues16
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01351","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues680
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

259015

PDB entries from 2026-09-02

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