9G4A

Structure of human SETD2 T1663M mutant in complex with SAM and H3K36M peptide

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	117
Details	Domain: {"description":"SET","evidences":[{"source":"PROSITE-ProRule","id":"PRU00190","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Domain: {"description":"Post-SET","evidences":[{"source":"PROSITE-ProRule","id":"PRU00155","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23043551","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27474439","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28256625","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FMU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H12","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5V21","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5V22","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23043551","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27474439","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28256625","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4H12","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5V22","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

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