9G2X

Cryo-EM structure of IrtAB in outward-occluded state in presence of mycobactin under turnover conditions in LMNG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0055085	biological_process	transmembrane transport
A	0140359	molecular_function	ABC-type transporter activity
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006869	biological_process	lipid transport
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
B	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
B	0055085	biological_process	transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGERQRVTIARAI

Chain	Residue	Details
A	LEU790-ILE804
B	LEU468-LEU482

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	437
Details	TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:32296173

Chain	Residue	Details
B	MET1-LEU25
B	THR70-GLY126
B	GLY169-GLN241
B	ALA294-ARG579
A	LEU558-VAL578
A	LEU587-GLY607

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site_id	SWS_FT_FI2
Number of Residues	120
Details	TRANSMEM: Helical => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	LEU26-PHE46
B	THR49-VAL69
B	LEU127-VAL147
B	ALA148-PHE168
B	VAL242-LEU262
B	ALA273-LEU293

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site_id	SWS_FT_FI3
Number of Residues	10
Details	TOPO_DOM: Periplasmic => ECO:0000305|PubMed:32296173

Chain	Residue	Details
B	SER47-ASP48
B	THR263-GLU272
A	LEU608-ARG908

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434

Chain	Residue	Details
B	GLY364

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