9G2C
Yeast RNA polymerase I elongation complex stalled by an apurinic site, open state
Functional Information from PROSITE/UniProt
| site_id | PS00446 |
| Number of Residues | 41 |
| Details | RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NAFRRimisevpsvAaeyVyffnNtSviqDEvLAhRIGLVP |
| Chain | Residue | Details |
| C | ASN65-PRO105 |
| site_id | PS00466 |
| Number of Residues | 36 |
| Details | ZF_TFIIS_1 Zinc finger TFIIS-type signature. CpqCgneemnyhtLQLRSaDEGatvfytCts...CgykF |
| Chain | Residue | Details |
| I | CYS86-PHE121 |
| site_id | PS01030 |
| Number of Residues | 25 |
| Details | RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCLDCGDLLenpnavlgsnve..CsqC |
| Chain | Residue | Details |
| I | PHE9-CYS33 |
| site_id | PS01110 |
| Number of Residues | 14 |
| Details | RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHirLssDE |
| Chain | Residue | Details |
| E | HIS147-GLU160 |
| site_id | PS01111 |
| Number of Residues | 15 |
| Details | RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ |
| Chain | Residue | Details |
| F | THR86-GLN100 |
| site_id | PS01112 |
| Number of Residues | 10 |
| Details | RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IVPVrCFSCG |
| Chain | Residue | Details |
| J | ILE2-GLY11 |
| site_id | PS01154 |
| Number of Residues | 32 |
| Details | RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. IveEdHTLgNaLryvImknpdVefcgYsipHP |
| Chain | Residue | Details |
| K | ILE65-PRO96 |
| site_id | PS01166 |
| Number of Residues | 13 |
| Details | RNA_POL_BETA RNA polymerases beta chain signature. GdKFSSrHGQKGV |
| Chain | Residue | Details |
| B | GLY914-VAL926 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Region: {"description":"Bridging helix","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Region: {"description":"Leucine-zipper"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 23 |
| Details | Region: {"description":"Non-specific ssDNA binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 43 |
| Details | Zinc finger: {"description":"C4-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10145","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15537538","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TWF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
