Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9FSP

RNA Polymerase III Class III Open Pre-initation Complex 2 (OC2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0002376	biological_process	immune system process
A	0003677	molecular_function	DNA binding
A	0003682	molecular_function	chromatin binding
A	0003899	molecular_function	DNA-directed RNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005666	cellular_component	RNA polymerase III complex
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0008270	molecular_function	zinc ion binding
A	0010628	biological_process	positive regulation of gene expression
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0032728	biological_process	positive regulation of interferon-beta production
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0042797	biological_process	tRNA transcription by RNA polymerase III
A	0045087	biological_process	innate immune response
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus
A	0071667	molecular_function	DNA/RNA hybrid binding
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0002376	biological_process	immune system process
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed RNA polymerase activity
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005666	cellular_component	RNA polymerase III complex
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006383	biological_process	transcription by RNA polymerase III
B	0008270	molecular_function	zinc ion binding
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0032549	molecular_function	ribonucleoside binding
B	0032728	biological_process	positive regulation of interferon-beta production
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0042796	biological_process	snRNA transcription by RNA polymerase III
B	0045087	biological_process	innate immune response
B	0045089	biological_process	positive regulation of innate immune response
B	0046872	molecular_function	metal ion binding
B	0051607	biological_process	defense response to virus
B	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
B	0071667	molecular_function	DNA/RNA hybrid binding
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0002376	biological_process	immune system process
C	0003677	molecular_function	DNA binding
C	0003697	molecular_function	single-stranded DNA binding
C	0003899	molecular_function	DNA-directed RNA polymerase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005666	cellular_component	RNA polymerase III complex
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006359	biological_process	regulation of transcription by RNA polymerase III
C	0032728	biological_process	positive regulation of interferon-beta production
C	0045087	biological_process	innate immune response
C	0045089	biological_process	positive regulation of innate immune response
C	0051607	biological_process	defense response to virus
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0002376	biological_process	immune system process
D	0003677	molecular_function	DNA binding
D	0003682	molecular_function	chromatin binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005666	cellular_component	RNA polymerase III complex
D	0005829	cellular_component	cytosol
D	0006383	biological_process	transcription by RNA polymerase III
D	0032728	biological_process	positive regulation of interferon-beta production
D	0042797	biological_process	tRNA transcription by RNA polymerase III
D	0045087	biological_process	innate immune response
D	0045089	biological_process	positive regulation of innate immune response
D	0051607	biological_process	defense response to virus
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0002376	biological_process	immune system process
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005666	cellular_component	RNA polymerase III complex
E	0005829	cellular_component	cytosol
E	0006351	biological_process	DNA-templated transcription
E	0045087	biological_process	innate immune response
E	0051607	biological_process	defense response to virus
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0002376	biological_process	immune system process
F	0003677	molecular_function	DNA binding
F	0003690	molecular_function	double-stranded DNA binding
F	0003899	molecular_function	DNA-directed RNA polymerase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005666	cellular_component	RNA polymerase III complex
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006359	biological_process	regulation of transcription by RNA polymerase III
F	0006383	biological_process	transcription by RNA polymerase III
F	0032728	biological_process	positive regulation of interferon-beta production
F	0045087	biological_process	innate immune response
F	0045089	biological_process	positive regulation of innate immune response
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
F	0051607	biological_process	defense response to virus
G	0000428	cellular_component	DNA-directed RNA polymerase complex
G	0002376	biological_process	immune system process
G	0003682	molecular_function	chromatin binding
G	0003899	molecular_function	DNA-directed RNA polymerase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005666	cellular_component	RNA polymerase III complex
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006359	biological_process	regulation of transcription by RNA polymerase III
G	0006383	biological_process	transcription by RNA polymerase III
G	0008283	biological_process	cell population proliferation
G	0016604	cellular_component	nuclear body
G	0032728	biological_process	positive regulation of interferon-beta production
G	0045087	biological_process	innate immune response
G	0045089	biological_process	positive regulation of innate immune response
G	0051607	biological_process	defense response to virus
H	0000428	cellular_component	DNA-directed RNA polymerase complex
H	0002376	biological_process	immune system process
H	0003677	molecular_function	DNA binding
H	0003899	molecular_function	DNA-directed RNA polymerase activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005666	cellular_component	RNA polymerase III complex
H	0005813	cellular_component	centrosome
H	0005829	cellular_component	cytosol
H	0006139	biological_process	nucleobase-containing compound metabolic process
H	0006351	biological_process	DNA-templated transcription
H	0006352	biological_process	DNA-templated transcription initiation
H	0006383	biological_process	transcription by RNA polymerase III
H	0006384	biological_process	transcription initiation at RNA polymerase III promoter
H	0045087	biological_process	innate immune response
H	0051607	biological_process	defense response to virus
I	0000166	molecular_function	nucleotide binding
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001635	molecular_function	calcitonin gene-related peptide receptor activity
I	0001669	cellular_component	acrosomal vesicle
I	0002376	biological_process	immune system process
I	0003899	molecular_function	DNA-directed RNA polymerase activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005666	cellular_component	RNA polymerase III complex
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006352	biological_process	DNA-templated transcription initiation
I	0006383	biological_process	transcription by RNA polymerase III
I	0006384	biological_process	transcription initiation at RNA polymerase III promoter
I	0007218	biological_process	neuropeptide signaling pathway
I	0009360	cellular_component	DNA polymerase III complex
I	0016020	cellular_component	membrane
I	0030880	cellular_component	RNA polymerase complex
I	0045087	biological_process	innate immune response
I	0051607	biological_process	defense response to virus
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0002376	biological_process	immune system process
J	0003676	molecular_function	nucleic acid binding
J	0003899	molecular_function	DNA-directed RNA polymerase activity
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005666	cellular_component	RNA polymerase III complex
J	0005829	cellular_component	cytosol
J	0006351	biological_process	DNA-templated transcription
J	0006383	biological_process	transcription by RNA polymerase III
J	0008270	molecular_function	zinc ion binding
J	0045087	biological_process	innate immune response
J	0046872	molecular_function	metal ion binding
J	0051607	biological_process	defense response to virus
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0001650	cellular_component	fibrillar center
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed RNA polymerase activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005666	cellular_component	RNA polymerase III complex
K	0005730	cellular_component	nucleolus
K	0005736	cellular_component	RNA polymerase I complex
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006351	biological_process	DNA-templated transcription
K	0006360	biological_process	transcription by RNA polymerase I
K	0046983	molecular_function	protein dimerization activity
L	0000428	cellular_component	DNA-directed RNA polymerase complex
L	0003677	molecular_function	DNA binding
L	0003899	molecular_function	DNA-directed RNA polymerase activity
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005666	cellular_component	RNA polymerase III complex
L	0005730	cellular_component	nucleolus
L	0005736	cellular_component	RNA polymerase I complex
L	0006351	biological_process	DNA-templated transcription
L	0006362	biological_process	transcription elongation by RNA polymerase I
L	0006383	biological_process	transcription by RNA polymerase III
L	0046983	molecular_function	protein dimerization activity
L	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
M	0000428	cellular_component	DNA-directed RNA polymerase complex
M	0003677	molecular_function	DNA binding
M	0003899	molecular_function	DNA-directed RNA polymerase activity
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005665	cellular_component	RNA polymerase II, core complex
M	0005666	cellular_component	RNA polymerase III complex
M	0005730	cellular_component	nucleolus
M	0005736	cellular_component	RNA polymerase I complex
M	0005829	cellular_component	cytosol
M	0006351	biological_process	DNA-templated transcription
M	0006362	biological_process	transcription elongation by RNA polymerase I
M	0006366	biological_process	transcription by RNA polymerase II
M	0042797	biological_process	tRNA transcription by RNA polymerase III
M	0050821	biological_process	protein stabilization
M	1990062	cellular_component	RPAP3/R2TP/prefoldin-like complex
N	0000428	cellular_component	DNA-directed RNA polymerase complex
N	0001650	cellular_component	fibrillar center
N	0003677	molecular_function	DNA binding
N	0003899	molecular_function	DNA-directed RNA polymerase activity
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005665	cellular_component	RNA polymerase II, core complex
N	0005666	cellular_component	RNA polymerase III complex
N	0005730	cellular_component	nucleolus
N	0005736	cellular_component	RNA polymerase I complex
N	0005829	cellular_component	cytosol
N	0006351	biological_process	DNA-templated transcription
N	0006360	biological_process	transcription by RNA polymerase I
N	0006366	biological_process	transcription by RNA polymerase II
N	0042797	biological_process	tRNA transcription by RNA polymerase III
O	0000428	cellular_component	DNA-directed RNA polymerase complex
O	0003677	molecular_function	DNA binding
O	0003697	molecular_function	single-stranded DNA binding
O	0003899	molecular_function	DNA-directed RNA polymerase activity
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005665	cellular_component	RNA polymerase II, core complex
O	0005666	cellular_component	RNA polymerase III complex
O	0005730	cellular_component	nucleolus
O	0005736	cellular_component	RNA polymerase I complex
O	0005829	cellular_component	cytosol
O	0006351	biological_process	DNA-templated transcription
O	0006366	biological_process	transcription by RNA polymerase II
O	0032993	cellular_component	protein-DNA complex
P	0000428	cellular_component	DNA-directed RNA polymerase complex
P	0003677	molecular_function	DNA binding
P	0003899	molecular_function	DNA-directed RNA polymerase activity
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005665	cellular_component	RNA polymerase II, core complex
P	0005666	cellular_component	RNA polymerase III complex
P	0005730	cellular_component	nucleolus
P	0005736	cellular_component	RNA polymerase I complex
P	0005829	cellular_component	cytosol
P	0006351	biological_process	DNA-templated transcription
P	0006356	biological_process	regulation of transcription by RNA polymerase I
P	0006366	biological_process	transcription by RNA polymerase II
P	0006383	biological_process	transcription by RNA polymerase III
P	0008270	molecular_function	zinc ion binding
P	0046872	molecular_function	metal ion binding
Q	0000428	cellular_component	DNA-directed RNA polymerase complex
Q	0003677	molecular_function	DNA binding
Q	0003899	molecular_function	DNA-directed RNA polymerase activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005665	cellular_component	RNA polymerase II, core complex
Q	0005666	cellular_component	RNA polymerase III complex
Q	0005730	cellular_component	nucleolus
Q	0005736	cellular_component	RNA polymerase I complex
Q	0005829	cellular_component	cytosol
Q	0006351	biological_process	DNA-templated transcription
Q	0006356	biological_process	regulation of transcription by RNA polymerase I
Q	0006360	biological_process	transcription by RNA polymerase I
Q	0006366	biological_process	transcription by RNA polymerase II
Q	0008270	molecular_function	zinc ion binding
Q	0042797	biological_process	tRNA transcription by RNA polymerase III
Q	0046872	molecular_function	metal ion binding
R	0003677	molecular_function	DNA binding
R	0006352	biological_process	DNA-templated transcription initiation
S	0000126	cellular_component	transcription factor TFIIIB complex
S	0001006	molecular_function	RNA polymerase III type 3 promoter sequence-specific DNA binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0006352	biological_process	DNA-templated transcription initiation
S	0006359	biological_process	regulation of transcription by RNA polymerase III
S	0006366	biological_process	transcription by RNA polymerase II
S	0008270	molecular_function	zinc ion binding
S	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
S	0017025	molecular_function	TBP-class protein binding
S	0034599	biological_process	cellular response to oxidative stress
S	0046872	molecular_function	metal ion binding
S	0070897	biological_process	transcription preinitiation complex assembly
S	0097550	cellular_component	transcription preinitiation complex
U	0000995	molecular_function	RNA polymerase III general transcription initiation factor activity
U	0003677	molecular_function	DNA binding
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005730	cellular_component	nucleolus
U	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
U	0019185	cellular_component	snRNA-activating protein complex
U	0042795	biological_process	snRNA transcription by RNA polymerase II
U	0042796	biological_process	snRNA transcription by RNA polymerase III
U	0043565	molecular_function	sequence-specific DNA binding
W	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
W	0000995	molecular_function	RNA polymerase III general transcription initiation factor activity
W	0001006	molecular_function	RNA polymerase III type 3 promoter sequence-specific DNA binding
W	0003677	molecular_function	DNA binding
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
W	0019185	cellular_component	snRNA-activating protein complex
W	0042795	biological_process	snRNA transcription by RNA polymerase II
W	0042796	biological_process	snRNA transcription by RNA polymerase III
Z	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
Z	0000995	molecular_function	RNA polymerase III general transcription initiation factor activity
Z	0001006	molecular_function	RNA polymerase III type 3 promoter sequence-specific DNA binding
Z	0001046	molecular_function	core promoter sequence-specific DNA binding
Z	0003677	molecular_function	DNA binding
Z	0003681	molecular_function	bent DNA binding
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0006366	biological_process	transcription by RNA polymerase II
Z	0006383	biological_process	transcription by RNA polymerase III
Z	0009301	biological_process	snRNA transcription
Z	0016604	cellular_component	nuclear body
Z	0019185	cellular_component	snRNA-activating protein complex
Z	0042795	biological_process	snRNA transcription by RNA polymerase II
Z	0042796	biological_process	snRNA transcription by RNA polymerase III

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FRCVVFH

Chain	Residue	Details
H	PHE72-HIS78

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePRttaLIFsSGKMvctGAKseeqsrlAarkyarvV

Chain	Residue	Details
R	TYR192-VAL241
R	TYR283-LEU332

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NAFRRillaevptmAvekVlvynNtSivqDEiLAhRLGLIP

Chain	Residue	Details
K	ASN74-PRO114

site_id	PS00466
Number of Residues	38
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CpkCehprayfmqLQTRSaDEPmttfykCcnaq.CghrW

Chain	Residue	Details
J	CYS69-TRP106

site_id	PS00697
Number of Residues	9
Details	DNA_LIGASE_A1 ATP-dependent DNA ligase AMP-binding site. EEKTNGWRI

Chain	Residue	Details
T	GLU344-ILE352

site_id	PS01030
Number of Residues	25
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCPGCGNGLiveegqrchrfs..CntC

Chain	Residue	Details
J	PHE4-CYS28

site_id	PS01110
Number of Residues	14
Details	RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtkEE

Chain	Residue	Details
M	HIS142-GLU155

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ

Chain	Residue	Details
N	THR58-GLN72

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG

Chain	Residue	Details
Q	ILE2-GLY11

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. LheEdHTLgNsLrymImknpeVefcgYtttHP

Chain	Residue	Details
L	LEU44-PRO75

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFSSrHGQKGV

Chain	Residue	Details
B	GLY894-VAL906

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
G	THR133
W	TRP424-LEU447
W	TRP476-MET499
R	ASN257
R	ARG294

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
G	SER157
B	ARG213
B	ASP432
B	LYS1019
B	ARG1046

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:33558764, ECO:0000269\|PubMed:33558766, ECO:0007744\|PDB:7D58

Chain	Residue	Details
F	CYS296
F	CYS307
D	ARG99
J	CYS28

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0007744\|PubMed:22814378

Chain	Residue	Details
F	ALA2
D	LYS152
D	LYS160
D	LYS190
D	LYS199
D	LYS310

site_id	SWS_FT_FI5
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
F	LYS5
D	LYS396
A	LYS1323

site_id	SWS_FT_FI6
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:25772364, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
E	SER522
F	LYS7

site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
E	LYS171
E	LYS432

site_id	SWS_FT_FI8
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:25772364, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
D	LYS206
E	LYS659
A	ARG1305

site_id	SWS_FT_FI9
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:25114211, ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
E	LYS498
D	LYS302

site_id	SWS_FT_FI10
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25772364, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
D	LYS285
A	ASP503

site_id	SWS_FT_FI11
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269\|PubMed:33558764, ECO:0000269\|PubMed:33674783, ECO:0000269\|PubMed:34675218, ECO:0007744\|PDB:7AE1, ECO:0007744\|PDB:7DN3, ECO:0007744\|PDB:7FJJ

Chain	Residue	Details
B	CYS1083

site_id	SWS_FT_FI12
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:33558764, ECO:0000269\|PubMed:33558766, ECO:0000269\|PubMed:33674783, ECO:0000269\|PubMed:34675218, ECO:0007744\|PDB:7AE1, ECO:0007744\|PDB:7D58, ECO:0007744\|PDB:7DN3, ECO:0007744\|PDB:7FJJ

Chain	Residue	Details
B	CYS1092
B	CYS1095

site_id	SWS_FT_FI13
Number of Residues	1
Details	SITE: Critical in trapping poly(dT) in Pol III-mediated transcription termination => ECO:0000305\|PubMed:34675218

Chain	Residue	Details
B	PHE429

site_id	SWS_FT_FI14
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
A	LYS445

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)