9FS2
Mutant S1538A of the dihydroorotase domain of human CAD protein bound to substrate
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: For DHOase activity => ECO:0000250|UniProtKB:P05020 |
| Chain | Residue | Details |
| A | ASP1686 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24332717, ECO:0007744|PDB:4C6D |
| Chain | Residue | Details |
| A | HIS1471 | |
| A | HIS1473 | |
| A | HIS1590 | |
| A | CYS1613 | |
| A | HIS1614 | |
| A | GLU1637 | |
| A | ASP1686 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24332717, ECO:0007744|PDB:4C6Q |
| Chain | Residue | Details |
| A | ARG1475 | |
| A | ASN1505 | |
| A | ARG1661 | |
| A | HIS1690 | |
| A | PRO1702 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: via carbamate group => ECO:0000269|PubMed:24332717, ECO:0007744|PDB:4C6D |
| Chain | Residue | Details |
| A | KCX1556 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-carboxylysine => ECO:0000269|PubMed:24332717 |
| Chain | Residue | Details |
| A | KCX1556 |
