9FQI
E3 ligase Cbl-b in complex with a lactam scaffold inhibitor (compound 7)
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
site_id | PS00518 |
Number of Residues | 10 |
Details | ZF_RING_1 Zinc finger RING-type signature. CgHlMCtsCL |
Chain | Residue | Details |
A | CYS388-LEU397 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 39 |
Details | ZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175 |
Chain | Residue | Details |
A | CYS373-ARG412 |
site_id | SWS_FT_FI2 |
Number of Residues | 5 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:P22681 |
Chain | Residue | Details |
A | ASP221 | |
A | THR223 | |
A | ASN225 | |
A | TYR227 | |
A | GLU232 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ARG286 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine; by PKC/PRKCQ => ECO:0000269|PubMed:19549985 |
Chain | Residue | Details |
A | SER282 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | MOD_RES: Phosphotyrosine => ECO:0000305|PubMed:20525694 |
Chain | Residue | Details |
A | TYR363 |