9FMD

Integrative model of the human post-catalytic spliceosome (P-complex)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003014	biological_process	renal system process
1	0003725	molecular_function	double-stranded RNA binding
1	0004860	molecular_function	protein kinase inhibitor activity
1	0005515	molecular_function	protein binding
1	0005634	cellular_component	nucleus
1	0005654	cellular_component	nucleoplasm
1	0005681	cellular_component	spliceosomal complex
1	0005730	cellular_component	nucleolus
1	0006397	biological_process	mRNA processing
1	0006469	biological_process	negative regulation of protein kinase activity
1	0008380	biological_process	RNA splicing
1	0019901	molecular_function	protein kinase binding
1	0042326	biological_process	negative regulation of phosphorylation
1	0070062	cellular_component	extracellular exosome
3	0000398	biological_process	mRNA splicing, via spliceosome
3	0003674	molecular_function	molecular_function
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005681	cellular_component	spliceosomal complex
3	0006397	biological_process	mRNA processing
3	0007399	biological_process	nervous system development
3	0008380	biological_process	RNA splicing
3	0071013	cellular_component	catalytic step 2 spliceosome
32	0003723	molecular_function	RNA binding
32	0005515	molecular_function	protein binding
32	0005634	cellular_component	nucleus
32	0005654	cellular_component	nucleoplasm
32	0005730	cellular_component	nucleolus
32	0006915	biological_process	apoptotic process
32	0008150	biological_process	biological_process
50	0003723	molecular_function	RNA binding
50	0005515	molecular_function	protein binding
50	0005634	cellular_component	nucleus
50	0005654	cellular_component	nucleoplasm
50	0006325	biological_process	chromatin organization
50	0006397	biological_process	mRNA processing
50	0007283	biological_process	spermatogenesis
50	0008380	biological_process	RNA splicing
50	0043484	biological_process	regulation of RNA splicing
56	0005515	molecular_function	protein binding
56	0005634	cellular_component	nucleus
56	0005654	cellular_component	nucleoplasm
56	0005737	cellular_component	cytoplasm
56	0005783	cellular_component	endoplasmic reticulum
56	0005789	cellular_component	endoplasmic reticulum membrane
56	0005813	cellular_component	centrosome
56	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
56	0016020	cellular_component	membrane
56	0030674	molecular_function	protein-macromolecule adaptor activity
56	0032527	biological_process	protein exit from endoplasmic reticulum
56	0044297	cellular_component	cell body
56	0090158	biological_process	endoplasmic reticulum membrane organization
7	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
7	0000398	biological_process	mRNA splicing, via spliceosome
7	0003723	molecular_function	RNA binding
7	0003724	molecular_function	RNA helicase activity
7	0003729	molecular_function	mRNA binding
7	0004386	molecular_function	helicase activity
7	0005515	molecular_function	protein binding
7	0005524	molecular_function	ATP binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005681	cellular_component	spliceosomal complex
7	0005730	cellular_component	nucleolus
7	0005737	cellular_component	cytoplasm
7	0005829	cellular_component	cytosol
7	0006364	biological_process	rRNA processing
7	0006397	biological_process	mRNA processing
7	0006406	biological_process	mRNA export from nucleus
7	0006417	biological_process	regulation of translation
7	0008143	molecular_function	poly(A) binding
7	0008306	biological_process	associative learning
7	0008380	biological_process	RNA splicing
7	0010629	biological_process	negative regulation of gene expression
7	0014070	biological_process	response to organic cyclic compound
7	0016020	cellular_component	membrane
7	0016607	cellular_component	nuclear speck
7	0016787	molecular_function	hydrolase activity
7	0016887	molecular_function	ATP hydrolysis activity
7	0017148	biological_process	negative regulation of translation
7	0030425	cellular_component	dendrite
7	0035145	cellular_component	exon-exon junction complex
7	0035368	molecular_function	selenocysteine insertion sequence binding
7	0035613	molecular_function	RNA stem-loop binding
7	0035640	biological_process	exploration behavior
7	0043021	molecular_function	ribonucleoprotein complex binding
7	0043025	cellular_component	neuronal cell body
7	0045727	biological_process	positive regulation of translation
7	0048701	biological_process	embryonic cranial skeleton morphogenesis
7	0051028	biological_process	mRNA transport
7	0071006	cellular_component	U2-type catalytic step 1 spliceosome
7	0071013	cellular_component	catalytic step 2 spliceosome
7	0072715	biological_process	cellular response to selenite ion
7	0090394	biological_process	negative regulation of excitatory postsynaptic potential
7	0098794	cellular_component	postsynapse
7	0098978	cellular_component	glutamatergic synapse
7	0099578	biological_process	regulation of translation at postsynapse, modulating synaptic transmission
7	1904570	biological_process	negative regulation of selenocysteine incorporation
7	1990416	biological_process	cellular response to brain-derived neurotrophic factor stimulus
7	1990904	cellular_component	ribonucleoprotein complex
7	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
8	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
8	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
8	0000398	biological_process	mRNA splicing, via spliceosome
8	0003723	molecular_function	RNA binding
8	0003729	molecular_function	mRNA binding
8	0005515	molecular_function	protein binding
8	0005634	cellular_component	nucleus
8	0005654	cellular_component	nucleoplasm
8	0005681	cellular_component	spliceosomal complex
8	0005737	cellular_component	cytoplasm
8	0005829	cellular_component	cytosol
8	0006397	biological_process	mRNA processing
8	0006406	biological_process	mRNA export from nucleus
8	0006417	biological_process	regulation of translation
8	0008380	biological_process	RNA splicing
8	0016607	cellular_component	nuclear speck
8	0030425	cellular_component	dendrite
8	0035145	cellular_component	exon-exon junction complex
8	0043025	cellular_component	neuronal cell body
8	0050684	biological_process	regulation of mRNA processing
8	0051028	biological_process	mRNA transport
8	0071006	cellular_component	U2-type catalytic step 1 spliceosome
8	0071013	cellular_component	catalytic step 2 spliceosome
8	1990501	cellular_component	exon-exon junction subcomplex mago-y14
8	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
9	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
9	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
9	0000398	biological_process	mRNA splicing, via spliceosome
9	0003723	molecular_function	RNA binding
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005681	cellular_component	spliceosomal complex
9	0005737	cellular_component	cytoplasm
9	0005829	cellular_component	cytosol
9	0006397	biological_process	mRNA processing
9	0006406	biological_process	mRNA export from nucleus
9	0006417	biological_process	regulation of translation
9	0008380	biological_process	RNA splicing
9	0016607	cellular_component	nuclear speck
9	0035145	cellular_component	exon-exon junction complex
9	0050684	biological_process	regulation of mRNA processing
9	0051028	biological_process	mRNA transport
9	0071013	cellular_component	catalytic step 2 spliceosome
9	1990501	cellular_component	exon-exon junction subcomplex mago-y14
9	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
a	0000243	cellular_component	commitment complex
a	0000387	biological_process	spliceosomal snRNP assembly
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005682	cellular_component	U5 snRNP
a	0005683	cellular_component	U7 snRNP
a	0005684	cellular_component	U2-type spliceosomal complex
a	0005685	cellular_component	U1 snRNP
a	0005686	cellular_component	U2 snRNP
a	0005687	cellular_component	U4 snRNP
a	0005689	cellular_component	U12-type spliceosomal complex
a	0005697	cellular_component	telomerase holoenzyme complex
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006397	biological_process	mRNA processing
a	0006479	biological_process	protein methylation
a	0008380	biological_process	RNA splicing
a	0016604	cellular_component	nuclear body
a	0019899	molecular_function	enzyme binding
a	0030532	cellular_component	small nuclear ribonucleoprotein complex
a	0034709	cellular_component	methylosome
a	0034715	cellular_component	pICln-Sm protein complex
a	0034719	cellular_component	SMN-Sm protein complex
a	0036261	biological_process	7-methylguanosine cap hypermethylation
a	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0070034	molecular_function	telomerase RNA binding
a	0071005	cellular_component	U2-type precatalytic spliceosome
a	0071007	cellular_component	U2-type catalytic step 2 spliceosome
a	0071011	cellular_component	precatalytic spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0071208	molecular_function	histone pre-mRNA DCP binding
a	0071209	molecular_function	U7 snRNA binding
a	0097526	cellular_component	spliceosomal tri-snRNP complex
a	1903241	biological_process	U2-type prespliceosome assembly
a	1990446	molecular_function	U1 snRNP binding
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008380	biological_process	RNA splicing
A	0016020	cellular_component	membrane
A	0016607	cellular_component	nuclear speck
A	0017070	molecular_function	U6 snRNA binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0097157	molecular_function	pre-mRNA intronic binding
A	0140492	molecular_function	metal-dependent deubiquitinase activity
b	0000387	biological_process	spliceosomal snRNP assembly
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005682	cellular_component	U5 snRNP
b	0005683	cellular_component	U7 snRNP
b	0005684	cellular_component	U2-type spliceosomal complex
b	0005685	cellular_component	U1 snRNP
b	0005686	cellular_component	U2 snRNP
b	0005687	cellular_component	U4 snRNP
b	0005689	cellular_component	U12-type spliceosomal complex
b	0005697	cellular_component	telomerase holoenzyme complex
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006397	biological_process	mRNA processing
b	0006479	biological_process	protein methylation
b	0008380	biological_process	RNA splicing
b	0030532	cellular_component	small nuclear ribonucleoprotein complex
b	0034709	cellular_component	methylosome
b	0034719	cellular_component	SMN-Sm protein complex
b	0036261	biological_process	7-methylguanosine cap hypermethylation
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0070034	molecular_function	telomerase RNA binding
b	0070990	molecular_function	snRNP binding
b	0071004	cellular_component	U2-type prespliceosome
b	0071005	cellular_component	U2-type precatalytic spliceosome
b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
b	0071208	molecular_function	histone pre-mRNA DCP binding
b	1903241	biological_process	U2-type prespliceosome assembly
b	1990446	molecular_function	U1 snRNP binding
b	1990447	molecular_function	U2 snRNP binding
B	0000354	biological_process	cis assembly of pre-catalytic spliceosome
B	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0001649	biological_process	osteoblast differentiation
B	0003723	molecular_function	RNA binding
B	0003724	molecular_function	RNA helicase activity
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0042802	molecular_function	identical protein binding
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
c	0000243	cellular_component	commitment complex
c	0000245	biological_process	spliceosomal complex assembly
c	0000387	biological_process	spliceosomal snRNP assembly
c	0000398	biological_process	mRNA splicing, via spliceosome
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005681	cellular_component	spliceosomal complex
c	0005682	cellular_component	U5 snRNP
c	0005684	cellular_component	U2-type spliceosomal complex
c	0005685	cellular_component	U1 snRNP
c	0005686	cellular_component	U2 snRNP
c	0005687	cellular_component	U4 snRNP
c	0005689	cellular_component	U12-type spliceosomal complex
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0006397	biological_process	mRNA processing
c	0008380	biological_process	RNA splicing
c	0030532	cellular_component	small nuclear ribonucleoprotein complex
c	0034709	cellular_component	methylosome
c	0034715	cellular_component	pICln-Sm protein complex
c	0034719	cellular_component	SMN-Sm protein complex
c	0036261	biological_process	7-methylguanosine cap hypermethylation
c	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
c	0071005	cellular_component	U2-type precatalytic spliceosome
c	0071007	cellular_component	U2-type catalytic step 2 spliceosome
c	0071011	cellular_component	precatalytic spliceosome
c	0071013	cellular_component	catalytic step 2 spliceosome
c	0097526	cellular_component	spliceosomal tri-snRNP complex
c	1903241	biological_process	U2-type prespliceosome assembly
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0015030	cellular_component	Cajal body
C	0016020	cellular_component	membrane
C	0016607	cellular_component	nuclear speck
C	0030623	molecular_function	U5 snRNA binding
C	0042220	biological_process	response to cocaine
C	0043231	cellular_component	intracellular membrane-bounded organelle
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071466	biological_process	cellular response to xenobiotic stimulus
d	0000245	biological_process	spliceosomal complex assembly
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005684	cellular_component	U2-type spliceosomal complex
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005689	cellular_component	U12-type spliceosomal complex
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0006397	biological_process	mRNA processing
d	0008380	biological_process	RNA splicing
d	0030532	cellular_component	small nuclear ribonucleoprotein complex
d	0034709	cellular_component	methylosome
d	0034715	cellular_component	pICln-Sm protein complex
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0070062	cellular_component	extracellular exosome
d	0071005	cellular_component	U2-type precatalytic spliceosome
d	0071007	cellular_component	U2-type catalytic step 2 spliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	1903241	biological_process	U2-type prespliceosome assembly
D	0000350	biological_process	generation of catalytic spliceosome for second transesterification step
D	0000389	biological_process	mRNA 3'-splice site recognition
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0000974	cellular_component	Prp19 complex
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0071006	cellular_component	U2-type catalytic step 1 spliceosome
D	0071013	cellular_component	catalytic step 2 spliceosome
D	0071014	cellular_component	post-mRNA release spliceosomal complex
D	0071020	cellular_component	post-spliceosomal complex
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005683	cellular_component	U7 snRNP
e	0005684	cellular_component	U2-type spliceosomal complex
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005689	cellular_component	U12-type spliceosomal complex
e	0005697	cellular_component	telomerase holoenzyme complex
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0030532	cellular_component	small nuclear ribonucleoprotein complex
e	0034709	cellular_component	methylosome
e	0034715	cellular_component	pICln-Sm protein complex
e	0034719	cellular_component	SMN-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0071005	cellular_component	U2-type precatalytic spliceosome
e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	1903241	biological_process	U2-type prespliceosome assembly
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005682	cellular_component	U5 snRNP
E	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
E	0005829	cellular_component	cytosol
E	0006396	biological_process	RNA processing
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0016607	cellular_component	nuclear speck
E	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
E	0071007	cellular_component	U2-type catalytic step 2 spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005683	cellular_component	U7 snRNP
f	0005684	cellular_component	U2-type spliceosomal complex
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005689	cellular_component	U12-type spliceosomal complex
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0006397	biological_process	mRNA processing
f	0008380	biological_process	RNA splicing
f	0030532	cellular_component	small nuclear ribonucleoprotein complex
f	0034709	cellular_component	methylosome
f	0034715	cellular_component	pICln-Sm protein complex
f	0034719	cellular_component	SMN-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0071005	cellular_component	U2-type precatalytic spliceosome
f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0120114	cellular_component	Sm-like protein family complex
f	1903241	biological_process	U2-type prespliceosome assembly
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0001933	biological_process	negative regulation of protein phosphorylation
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006397	biological_process	mRNA processing
F	0008380	biological_process	RNA splicing
F	0016607	cellular_component	nuclear speck
F	0031665	biological_process	negative regulation of lipopolysaccharide-mediated signaling pathway
F	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
F	0032688	biological_process	negative regulation of interferon-beta production
F	0032717	biological_process	negative regulation of interleukin-8 production
F	0032720	biological_process	negative regulation of tumor necrosis factor production
F	0034122	biological_process	negative regulation of toll-like receptor signaling pathway
F	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
F	0045087	biological_process	innate immune response
F	0045292	biological_process	mRNA cis splicing, via spliceosome
F	0045824	biological_process	negative regulation of innate immune response
F	0060339	biological_process	negative regulation of type I interferon-mediated signaling pathway
F	0071013	cellular_component	catalytic step 2 spliceosome
F	0071222	biological_process	cellular response to lipopolysaccharide
F	0071347	biological_process	cellular response to interleukin-1
F	0071356	biological_process	cellular response to tumor necrosis factor
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005683	cellular_component	U7 snRNP
g	0005684	cellular_component	U2-type spliceosomal complex
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005689	cellular_component	U12-type spliceosomal complex
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006397	biological_process	mRNA processing
g	0008380	biological_process	RNA splicing
g	0030532	cellular_component	small nuclear ribonucleoprotein complex
g	0034709	cellular_component	methylosome
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0043186	cellular_component	P granule
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0071004	cellular_component	U2-type prespliceosome
g	0071005	cellular_component	U2-type precatalytic spliceosome
g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
h	0000243	cellular_component	commitment complex
h	0000387	biological_process	spliceosomal snRNP assembly
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0003723	molecular_function	RNA binding
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005681	cellular_component	spliceosomal complex
h	0005682	cellular_component	U5 snRNP
h	0005683	cellular_component	U7 snRNP
h	0005684	cellular_component	U2-type spliceosomal complex
h	0005685	cellular_component	U1 snRNP
h	0005686	cellular_component	U2 snRNP
h	0005687	cellular_component	U4 snRNP
h	0005689	cellular_component	U12-type spliceosomal complex
h	0005697	cellular_component	telomerase holoenzyme complex
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0006397	biological_process	mRNA processing
h	0006479	biological_process	protein methylation
h	0008380	biological_process	RNA splicing
h	0016604	cellular_component	nuclear body
h	0019899	molecular_function	enzyme binding
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0034709	cellular_component	methylosome
h	0034715	cellular_component	pICln-Sm protein complex
h	0034719	cellular_component	SMN-Sm protein complex
h	0036261	biological_process	7-methylguanosine cap hypermethylation
h	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
h	0070034	molecular_function	telomerase RNA binding
h	0071005	cellular_component	U2-type precatalytic spliceosome
h	0071007	cellular_component	U2-type catalytic step 2 spliceosome
h	0071011	cellular_component	precatalytic spliceosome
h	0071013	cellular_component	catalytic step 2 spliceosome
h	0071208	molecular_function	histone pre-mRNA DCP binding
h	0071209	molecular_function	U7 snRNA binding
h	0097526	cellular_component	spliceosomal tri-snRNP complex
h	1903241	biological_process	U2-type prespliceosome assembly
h	1990446	molecular_function	U1 snRNP binding
H	0000398	biological_process	mRNA splicing, via spliceosome
H	0003723	molecular_function	RNA binding
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005681	cellular_component	spliceosomal complex
H	0005829	cellular_component	cytosol
H	0006397	biological_process	mRNA processing
H	0008380	biological_process	RNA splicing
H	0016607	cellular_component	nuclear speck
H	0048024	biological_process	regulation of mRNA splicing, via spliceosome
H	0071005	cellular_component	U2-type precatalytic spliceosome
H	0071006	cellular_component	U2-type catalytic step 1 spliceosome
H	0071007	cellular_component	U2-type catalytic step 2 spliceosome
H	0071013	cellular_component	catalytic step 2 spliceosome
i	0000387	biological_process	spliceosomal snRNP assembly
i	0000398	biological_process	mRNA splicing, via spliceosome
i	0003723	molecular_function	RNA binding
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005681	cellular_component	spliceosomal complex
i	0005682	cellular_component	U5 snRNP
i	0005683	cellular_component	U7 snRNP
i	0005684	cellular_component	U2-type spliceosomal complex
i	0005685	cellular_component	U1 snRNP
i	0005686	cellular_component	U2 snRNP
i	0005687	cellular_component	U4 snRNP
i	0005689	cellular_component	U12-type spliceosomal complex
i	0005697	cellular_component	telomerase holoenzyme complex
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0006397	biological_process	mRNA processing
i	0006479	biological_process	protein methylation
i	0008380	biological_process	RNA splicing
i	0030532	cellular_component	small nuclear ribonucleoprotein complex
i	0034709	cellular_component	methylosome
i	0034719	cellular_component	SMN-Sm protein complex
i	0036261	biological_process	7-methylguanosine cap hypermethylation
i	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
i	0070034	molecular_function	telomerase RNA binding
i	0070990	molecular_function	snRNP binding
i	0071004	cellular_component	U2-type prespliceosome
i	0071005	cellular_component	U2-type precatalytic spliceosome
i	0071007	cellular_component	U2-type catalytic step 2 spliceosome
i	0071013	cellular_component	catalytic step 2 spliceosome
i	0071204	cellular_component	histone pre-mRNA 3'end processing complex
i	0071208	molecular_function	histone pre-mRNA DCP binding
i	1903241	biological_process	U2-type prespliceosome assembly
i	1990446	molecular_function	U1 snRNP binding
i	1990447	molecular_function	U2 snRNP binding
I	0000349	biological_process	generation of catalytic spliceosome for first transesterification step
I	0000398	biological_process	mRNA splicing, via spliceosome
I	0000974	cellular_component	Prp19 complex
I	0001824	biological_process	blastocyst development
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005681	cellular_component	spliceosomal complex
I	0006281	biological_process	DNA repair
I	0006283	biological_process	transcription-coupled nucleotide-excision repair
I	0006351	biological_process	DNA-templated transcription
I	0006397	biological_process	mRNA processing
I	0008380	biological_process	RNA splicing
I	0016020	cellular_component	membrane
I	0043231	cellular_component	intracellular membrane-bounded organelle
I	0071007	cellular_component	U2-type catalytic step 2 spliceosome
I	0071013	cellular_component	catalytic step 2 spliceosome
I	0071014	cellular_component	post-mRNA release spliceosomal complex
j	0000243	cellular_component	commitment complex
j	0000245	biological_process	spliceosomal complex assembly
j	0000387	biological_process	spliceosomal snRNP assembly
j	0000398	biological_process	mRNA splicing, via spliceosome
j	0003723	molecular_function	RNA binding
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005681	cellular_component	spliceosomal complex
j	0005682	cellular_component	U5 snRNP
j	0005684	cellular_component	U2-type spliceosomal complex
j	0005685	cellular_component	U1 snRNP
j	0005686	cellular_component	U2 snRNP
j	0005687	cellular_component	U4 snRNP
j	0005689	cellular_component	U12-type spliceosomal complex
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0006397	biological_process	mRNA processing
j	0008380	biological_process	RNA splicing
j	0030532	cellular_component	small nuclear ribonucleoprotein complex
j	0034709	cellular_component	methylosome
j	0034715	cellular_component	pICln-Sm protein complex
j	0034719	cellular_component	SMN-Sm protein complex
j	0036261	biological_process	7-methylguanosine cap hypermethylation
j	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
j	0071005	cellular_component	U2-type precatalytic spliceosome
j	0071007	cellular_component	U2-type catalytic step 2 spliceosome
j	0071011	cellular_component	precatalytic spliceosome
j	0071013	cellular_component	catalytic step 2 spliceosome
j	0097526	cellular_component	spliceosomal tri-snRNP complex
j	1903241	biological_process	U2-type prespliceosome assembly
J	0000245	biological_process	spliceosomal complex assembly
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0000974	cellular_component	Prp19 complex
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005681	cellular_component	spliceosomal complex
J	0006397	biological_process	mRNA processing
J	0008380	biological_process	RNA splicing
J	0016607	cellular_component	nuclear speck
J	0071007	cellular_component	U2-type catalytic step 2 spliceosome
J	0071013	cellular_component	catalytic step 2 spliceosome
J	0071014	cellular_component	post-mRNA release spliceosomal complex
k	0000245	biological_process	spliceosomal complex assembly
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005684	cellular_component	U2-type spliceosomal complex
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005689	cellular_component	U12-type spliceosomal complex
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0006397	biological_process	mRNA processing
k	0008380	biological_process	RNA splicing
k	0030532	cellular_component	small nuclear ribonucleoprotein complex
k	0034709	cellular_component	methylosome
k	0034715	cellular_component	pICln-Sm protein complex
k	0034719	cellular_component	SMN-Sm protein complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0070062	cellular_component	extracellular exosome
k	0071005	cellular_component	U2-type precatalytic spliceosome
k	0071007	cellular_component	U2-type catalytic step 2 spliceosome
k	0071011	cellular_component	precatalytic spliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	1903241	biological_process	U2-type prespliceosome assembly
K	0000375	biological_process	RNA splicing, via transesterification reactions
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0000974	cellular_component	Prp19 complex
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005662	cellular_component	DNA replication factor A complex
K	0005681	cellular_component	spliceosomal complex
K	0005730	cellular_component	nucleolus
K	0005813	cellular_component	centrosome
K	0006397	biological_process	mRNA processing
K	0008380	biological_process	RNA splicing
K	0016607	cellular_component	nuclear speck
K	0071007	cellular_component	U2-type catalytic step 2 spliceosome
K	0071013	cellular_component	catalytic step 2 spliceosome
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005683	cellular_component	U7 snRNP
l	0005684	cellular_component	U2-type spliceosomal complex
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005689	cellular_component	U12-type spliceosomal complex
l	0005697	cellular_component	telomerase holoenzyme complex
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006397	biological_process	mRNA processing
l	0008380	biological_process	RNA splicing
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034709	cellular_component	methylosome
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0071005	cellular_component	U2-type precatalytic spliceosome
l	0071007	cellular_component	U2-type catalytic step 2 spliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	1903241	biological_process	U2-type prespliceosome assembly
L	0000077	biological_process	DNA damage checkpoint signaling
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0000974	cellular_component	Prp19 complex
L	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
L	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
L	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
L	0003677	molecular_function	DNA binding
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005662	cellular_component	DNA replication factor A complex
L	0005681	cellular_component	spliceosomal complex
L	0005737	cellular_component	cytoplasm
L	0006281	biological_process	DNA repair
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0016020	cellular_component	membrane
L	0016607	cellular_component	nuclear speck
L	0042802	molecular_function	identical protein binding
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0071007	cellular_component	U2-type catalytic step 2 spliceosome
L	0071013	cellular_component	catalytic step 2 spliceosome
L	0071987	molecular_function	WD40-repeat domain binding
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005683	cellular_component	U7 snRNP
m	0005684	cellular_component	U2-type spliceosomal complex
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005689	cellular_component	U12-type spliceosomal complex
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0008380	biological_process	RNA splicing
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0034709	cellular_component	methylosome
m	0034715	cellular_component	pICln-Sm protein complex
m	0034719	cellular_component	SMN-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0071005	cellular_component	U2-type precatalytic spliceosome
m	0071007	cellular_component	U2-type catalytic step 2 spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	0120114	cellular_component	Sm-like protein family complex
m	1903241	biological_process	U2-type prespliceosome assembly
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0000974	cellular_component	Prp19 complex
M	0001701	biological_process	in utero embryonic development
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005681	cellular_component	spliceosomal complex
M	0006397	biological_process	mRNA processing
M	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
M	0007369	biological_process	gastrulation
M	0008284	biological_process	positive regulation of cell population proliferation
M	0008380	biological_process	RNA splicing
M	0016607	cellular_component	nuclear speck
M	0048568	biological_process	embryonic organ development
M	0071007	cellular_component	U2-type catalytic step 2 spliceosome
M	0071013	cellular_component	catalytic step 2 spliceosome
M	0071014	cellular_component	post-mRNA release spliceosomal complex
n	0000245	biological_process	spliceosomal complex assembly
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005683	cellular_component	U7 snRNP
n	0005684	cellular_component	U2-type spliceosomal complex
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005689	cellular_component	U12-type spliceosomal complex
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006397	biological_process	mRNA processing
n	0008380	biological_process	RNA splicing
n	0030532	cellular_component	small nuclear ribonucleoprotein complex
n	0034709	cellular_component	methylosome
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0043186	cellular_component	P granule
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0071004	cellular_component	U2-type prespliceosome
n	0071005	cellular_component	U2-type precatalytic spliceosome
n	0071007	cellular_component	U2-type catalytic step 2 spliceosome
n	0071011	cellular_component	precatalytic spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0097526	cellular_component	spliceosomal tri-snRNP complex
n	1903241	biological_process	U2-type prespliceosome assembly
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0000785	cellular_component	chromatin
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005681	cellular_component	spliceosomal complex
N	0006397	biological_process	mRNA processing
N	0008380	biological_process	RNA splicing
N	0016922	molecular_function	nuclear receptor binding
N	0030374	molecular_function	nuclear receptor coactivator activity
N	0045893	biological_process	positive regulation of DNA-templated transcription
N	0071007	cellular_component	U2-type catalytic step 2 spliceosome
N	2000825	biological_process	positive regulation of androgen receptor activity
NO	0000139	cellular_component	Golgi membrane
NO	0003723	molecular_function	RNA binding
NO	0005515	molecular_function	protein binding
NO	0005634	cellular_component	nucleus
NO	0005654	cellular_component	nucleoplasm
NO	0005737	cellular_component	cytoplasm
NO	0005829	cellular_component	cytosol
NO	0016740	molecular_function	transferase activity
NO	0043086	biological_process	negative regulation of catalytic activity
NO	0045428	biological_process	regulation of nitric oxide biosynthetic process
NO	0051001	biological_process	negative regulation of nitric-oxide synthase activity
NO	0140313	molecular_function	molecular sequestering activity
o	0000398	biological_process	mRNA splicing, via spliceosome
o	0003723	molecular_function	RNA binding
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005654	cellular_component	nucleoplasm
o	0005681	cellular_component	spliceosomal complex
o	0005684	cellular_component	U2-type spliceosomal complex
o	0005686	cellular_component	U2 snRNP
o	0006397	biological_process	mRNA processing
o	0007283	biological_process	spermatogenesis
o	0008380	biological_process	RNA splicing
o	0016604	cellular_component	nuclear body
o	0016607	cellular_component	nuclear speck
o	0030532	cellular_component	small nuclear ribonucleoprotein complex
o	0030620	molecular_function	U2 snRNA binding
o	0071005	cellular_component	U2-type precatalytic spliceosome
o	0071007	cellular_component	U2-type catalytic step 2 spliceosome
o	0071013	cellular_component	catalytic step 2 spliceosome
o	1903241	biological_process	U2-type prespliceosome assembly
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0000974	cellular_component	Prp19 complex
O	0003723	molecular_function	RNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005681	cellular_component	spliceosomal complex
O	0005737	cellular_component	cytoplasm
O	0006397	biological_process	mRNA processing
O	0008380	biological_process	RNA splicing
O	0017070	molecular_function	U6 snRNA binding
O	0033120	biological_process	positive regulation of RNA splicing
O	0036002	molecular_function	pre-mRNA binding
O	0042307	biological_process	positive regulation of protein import into nucleus
O	0045292	biological_process	mRNA cis splicing, via spliceosome
O	0046827	biological_process	positive regulation of protein export from nucleus
O	0046872	molecular_function	metal ion binding
O	0048306	molecular_function	calcium-dependent protein binding
O	0071006	cellular_component	U2-type catalytic step 1 spliceosome
O	0071007	cellular_component	U2-type catalytic step 2 spliceosome
O	0071013	cellular_component	catalytic step 2 spliceosome
O	0071466	biological_process	cellular response to xenobiotic stimulus
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0001650	cellular_component	fibrillar center
p	0003723	molecular_function	RNA binding
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0005681	cellular_component	spliceosomal complex
p	0005684	cellular_component	U2-type spliceosomal complex
p	0005685	cellular_component	U1 snRNP
p	0005686	cellular_component	U2 snRNP
p	0006397	biological_process	mRNA processing
p	0008380	biological_process	RNA splicing
p	0016607	cellular_component	nuclear speck
p	0030619	molecular_function	U1 snRNA binding
p	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
p	0071005	cellular_component	U2-type precatalytic spliceosome
p	0071007	cellular_component	U2-type catalytic step 2 spliceosome
p	0071013	cellular_component	catalytic step 2 spliceosome
p	1903241	biological_process	U2-type prespliceosome assembly
P	0000398	biological_process	mRNA splicing, via spliceosome
P	0000974	cellular_component	Prp19 complex
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005681	cellular_component	spliceosomal complex
P	0005739	cellular_component	mitochondrion
P	0006397	biological_process	mRNA processing
P	0008380	biological_process	RNA splicing
P	0016607	cellular_component	nuclear speck
P	0045292	biological_process	mRNA cis splicing, via spliceosome
P	0071007	cellular_component	U2-type catalytic step 2 spliceosome
P	0071013	cellular_component	catalytic step 2 spliceosome
q	0000077	biological_process	DNA damage checkpoint signaling
q	0000209	biological_process	protein polyubiquitination
q	0000244	biological_process	spliceosomal tri-snRNP complex assembly
q	0000245	biological_process	spliceosomal complex assembly
q	0000398	biological_process	mRNA splicing, via spliceosome
q	0000974	cellular_component	Prp19 complex
q	0001833	biological_process	inner cell mass cell proliferation
q	0004842	molecular_function	ubiquitin-protein transferase activity
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005662	cellular_component	DNA replication factor A complex
q	0005681	cellular_component	spliceosomal complex
q	0005737	cellular_component	cytoplasm
q	0005811	cellular_component	lipid droplet
q	0005819	cellular_component	spindle
q	0005856	cellular_component	cytoskeleton
q	0006281	biological_process	DNA repair
q	0006303	biological_process	double-strand break repair via nonhomologous end joining
q	0006397	biological_process	mRNA processing
q	0008104	biological_process	protein localization
q	0008380	biological_process	RNA splicing
q	0008610	biological_process	lipid biosynthetic process
q	0010498	biological_process	proteasomal protein catabolic process
q	0016020	cellular_component	membrane
q	0016567	biological_process	protein ubiquitination
q	0016607	cellular_component	nuclear speck
q	0016740	molecular_function	transferase activity
q	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
q	0035861	cellular_component	site of double-strand break
q	0042802	molecular_function	identical protein binding
q	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
q	0061630	molecular_function	ubiquitin protein ligase activity
q	0070534	biological_process	protein K63-linked ubiquitination
q	0071006	cellular_component	U2-type catalytic step 1 spliceosome
q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
q	0071013	cellular_component	catalytic step 2 spliceosome
Q	0000398	biological_process	mRNA splicing, via spliceosome
Q	0003723	molecular_function	RNA binding
Q	0003724	molecular_function	RNA helicase activity
Q	0003727	molecular_function	single-stranded RNA binding
Q	0003729	molecular_function	mRNA binding
Q	0004386	molecular_function	helicase activity
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005681	cellular_component	spliceosomal complex
Q	0006397	biological_process	mRNA processing
Q	0008380	biological_process	RNA splicing
Q	0016020	cellular_component	membrane
Q	0016787	molecular_function	hydrolase activity
Q	0016887	molecular_function	ATP hydrolysis activity
Q	0034458	molecular_function	3'-5' RNA helicase activity
Q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
Q	0071013	cellular_component	catalytic step 2 spliceosome
r	0000077	biological_process	DNA damage checkpoint signaling
r	0000209	biological_process	protein polyubiquitination
r	0000244	biological_process	spliceosomal tri-snRNP complex assembly
r	0000245	biological_process	spliceosomal complex assembly
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0000974	cellular_component	Prp19 complex
r	0001833	biological_process	inner cell mass cell proliferation
r	0004842	molecular_function	ubiquitin-protein transferase activity
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005662	cellular_component	DNA replication factor A complex
r	0005681	cellular_component	spliceosomal complex
r	0005737	cellular_component	cytoplasm
r	0005811	cellular_component	lipid droplet
r	0005819	cellular_component	spindle
r	0005856	cellular_component	cytoskeleton
r	0006281	biological_process	DNA repair
r	0006303	biological_process	double-strand break repair via nonhomologous end joining
r	0006397	biological_process	mRNA processing
r	0008104	biological_process	protein localization
r	0008380	biological_process	RNA splicing
r	0008610	biological_process	lipid biosynthetic process
r	0010498	biological_process	proteasomal protein catabolic process
r	0016020	cellular_component	membrane
r	0016567	biological_process	protein ubiquitination
r	0016607	cellular_component	nuclear speck
r	0016740	molecular_function	transferase activity
r	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
r	0035861	cellular_component	site of double-strand break
r	0042802	molecular_function	identical protein binding
r	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
r	0061630	molecular_function	ubiquitin protein ligase activity
r	0070534	biological_process	protein K63-linked ubiquitination
r	0071006	cellular_component	U2-type catalytic step 1 spliceosome
r	0071007	cellular_component	U2-type catalytic step 2 spliceosome
r	0071013	cellular_component	catalytic step 2 spliceosome
R	0000122	biological_process	negative regulation of transcription by RNA polymerase II
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0003713	molecular_function	transcription coactivator activity
R	0003714	molecular_function	transcription corepressor activity
R	0003723	molecular_function	RNA binding
R	0005112	molecular_function	Notch binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005681	cellular_component	spliceosomal complex
R	0006357	biological_process	regulation of transcription by RNA polymerase II
R	0006397	biological_process	mRNA processing
R	0008024	cellular_component	cyclin/CDK positive transcription elongation factor complex
R	0008380	biological_process	RNA splicing
R	0016363	cellular_component	nuclear matrix
R	0016604	cellular_component	nuclear body
R	0016607	cellular_component	nuclear speck
R	0016922	molecular_function	nuclear receptor binding
R	0019899	molecular_function	enzyme binding
R	0030511	biological_process	positive regulation of transforming growth factor beta receptor signaling pathway
R	0042771	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
R	0042809	molecular_function	nuclear vitamin D receptor binding
R	0042974	molecular_function	nuclear retinoic acid receptor binding
R	0043923	biological_process	positive regulation by host of viral transcription
R	0045892	biological_process	negative regulation of DNA-templated transcription
R	0045944	biological_process	positive regulation of transcription by RNA polymerase II
R	0046332	molecular_function	SMAD binding
R	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
R	0048384	biological_process	retinoic acid receptor signaling pathway
R	0048385	biological_process	regulation of retinoic acid receptor signaling pathway
R	0050681	molecular_function	nuclear androgen receptor binding
R	0050769	biological_process	positive regulation of neurogenesis
R	0070562	biological_process	regulation of vitamin D receptor signaling pathway
R	0070564	biological_process	positive regulation of vitamin D receptor signaling pathway
R	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0071013	cellular_component	catalytic step 2 spliceosome
R	0071300	biological_process	cellular response to retinoic acid
s	0000077	biological_process	DNA damage checkpoint signaling
s	0000209	biological_process	protein polyubiquitination
s	0000244	biological_process	spliceosomal tri-snRNP complex assembly
s	0000245	biological_process	spliceosomal complex assembly
s	0000398	biological_process	mRNA splicing, via spliceosome
s	0000974	cellular_component	Prp19 complex
s	0001833	biological_process	inner cell mass cell proliferation
s	0004842	molecular_function	ubiquitin-protein transferase activity
s	0005515	molecular_function	protein binding
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0005662	cellular_component	DNA replication factor A complex
s	0005681	cellular_component	spliceosomal complex
s	0005737	cellular_component	cytoplasm
s	0005811	cellular_component	lipid droplet
s	0005819	cellular_component	spindle
s	0005856	cellular_component	cytoskeleton
s	0006281	biological_process	DNA repair
s	0006303	biological_process	double-strand break repair via nonhomologous end joining
s	0006397	biological_process	mRNA processing
s	0008104	biological_process	protein localization
s	0008380	biological_process	RNA splicing
s	0008610	biological_process	lipid biosynthetic process
s	0010498	biological_process	proteasomal protein catabolic process
s	0016020	cellular_component	membrane
s	0016567	biological_process	protein ubiquitination
s	0016607	cellular_component	nuclear speck
s	0016740	molecular_function	transferase activity
s	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
s	0035861	cellular_component	site of double-strand break
s	0042802	molecular_function	identical protein binding
s	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
s	0061630	molecular_function	ubiquitin protein ligase activity
s	0070534	biological_process	protein K63-linked ubiquitination
s	0071006	cellular_component	U2-type catalytic step 1 spliceosome
s	0071007	cellular_component	U2-type catalytic step 2 spliceosome
s	0071013	cellular_component	catalytic step 2 spliceosome
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0000413	biological_process	protein peptidyl-prolyl isomerization
S	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
S	0003824	molecular_function	catalytic activity
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005681	cellular_component	spliceosomal complex
S	0006397	biological_process	mRNA processing
S	0008380	biological_process	RNA splicing
S	0071007	cellular_component	U2-type catalytic step 2 spliceosome
S	0071013	cellular_component	catalytic step 2 spliceosome
S	0097718	molecular_function	disordered domain specific binding
S	1990403	biological_process	embryonic brain development
SR	0000398	biological_process	mRNA splicing, via spliceosome
SR	0003723	molecular_function	RNA binding
SR	0003729	molecular_function	mRNA binding
SR	0005515	molecular_function	protein binding
SR	0005634	cellular_component	nucleus
SR	0005654	cellular_component	nucleoplasm
SR	0005681	cellular_component	spliceosomal complex
SR	0006397	biological_process	mRNA processing
SR	0008380	biological_process	RNA splicing
SR	0015030	cellular_component	Cajal body
SR	0016607	cellular_component	nuclear speck
SR	0070742	molecular_function	C2H2 zinc finger domain binding
SR	0071005	cellular_component	U2-type precatalytic spliceosome
SR	0071007	cellular_component	U2-type catalytic step 2 spliceosome
SR	0071013	cellular_component	catalytic step 2 spliceosome
t	0000077	biological_process	DNA damage checkpoint signaling
t	0000209	biological_process	protein polyubiquitination
t	0000244	biological_process	spliceosomal tri-snRNP complex assembly
t	0000245	biological_process	spliceosomal complex assembly
t	0000398	biological_process	mRNA splicing, via spliceosome
t	0000974	cellular_component	Prp19 complex
t	0001833	biological_process	inner cell mass cell proliferation
t	0004842	molecular_function	ubiquitin-protein transferase activity
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005654	cellular_component	nucleoplasm
t	0005662	cellular_component	DNA replication factor A complex
t	0005681	cellular_component	spliceosomal complex
t	0005737	cellular_component	cytoplasm
t	0005811	cellular_component	lipid droplet
t	0005819	cellular_component	spindle
t	0005856	cellular_component	cytoskeleton
t	0006281	biological_process	DNA repair
t	0006303	biological_process	double-strand break repair via nonhomologous end joining
t	0006397	biological_process	mRNA processing
t	0008104	biological_process	protein localization
t	0008380	biological_process	RNA splicing
t	0008610	biological_process	lipid biosynthetic process
t	0010498	biological_process	proteasomal protein catabolic process
t	0016020	cellular_component	membrane
t	0016567	biological_process	protein ubiquitination
t	0016607	cellular_component	nuclear speck
t	0016740	molecular_function	transferase activity
t	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
t	0035861	cellular_component	site of double-strand break
t	0042802	molecular_function	identical protein binding
t	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
t	0061630	molecular_function	ubiquitin protein ligase activity
t	0070534	biological_process	protein K63-linked ubiquitination
t	0071006	cellular_component	U2-type catalytic step 1 spliceosome
t	0071007	cellular_component	U2-type catalytic step 2 spliceosome
t	0071013	cellular_component	catalytic step 2 spliceosome
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0000974	cellular_component	Prp19 complex
T	0001650	cellular_component	fibrillar center
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005662	cellular_component	DNA replication factor A complex
T	0005681	cellular_component	spliceosomal complex
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0016607	cellular_component	nuclear speck
T	0031965	cellular_component	nuclear membrane
T	0034504	biological_process	protein localization to nucleus
T	0071007	cellular_component	U2-type catalytic step 2 spliceosome
T	0071013	cellular_component	catalytic step 2 spliceosome
T	1900087	biological_process	positive regulation of G1/S transition of mitotic cell cycle
U	0000375	biological_process	RNA splicing, via transesterification reactions
U	0000380	biological_process	alternative mRNA splicing, via spliceosome
U	0000386	molecular_function	second spliceosomal transesterification activity
U	0000389	biological_process	mRNA 3'-splice site recognition
U	0000398	biological_process	mRNA splicing, via spliceosome
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005681	cellular_component	spliceosomal complex
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006397	biological_process	mRNA processing
U	0006886	biological_process	intracellular protein transport
U	0008270	molecular_function	zinc ion binding
U	0008380	biological_process	RNA splicing
U	0016020	cellular_component	membrane
U	0016607	cellular_component	nuclear speck
U	0030532	cellular_component	small nuclear ribonucleoprotein complex
U	0030628	molecular_function	pre-mRNA 3'-splice site binding
U	0034605	biological_process	cellular response to heat
U	0043231	cellular_component	intracellular membrane-bounded organelle
U	0046872	molecular_function	metal ion binding
U	0071013	cellular_component	catalytic step 2 spliceosome
V	0000390	biological_process	spliceosomal complex disassembly
V	0000398	biological_process	mRNA splicing, via spliceosome
V	0003723	molecular_function	RNA binding
V	0003724	molecular_function	RNA helicase activity
V	0004386	molecular_function	helicase activity
V	0005515	molecular_function	protein binding
V	0005524	molecular_function	ATP binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005681	cellular_component	spliceosomal complex
V	0005829	cellular_component	cytosol
V	0006396	biological_process	RNA processing
V	0006397	biological_process	mRNA processing
V	0008186	molecular_function	ATP-dependent activity, acting on RNA
V	0008380	biological_process	RNA splicing
V	0016604	cellular_component	nuclear body
V	0016787	molecular_function	hydrolase activity
V	0016887	molecular_function	ATP hydrolysis activity
V	0042802	molecular_function	identical protein binding
V	0071007	cellular_component	U2-type catalytic step 2 spliceosome
V	0071013	cellular_component	catalytic step 2 spliceosome
w	0000398	biological_process	mRNA splicing, via spliceosome
w	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
w	0003824	molecular_function	catalytic activity
w	0005634	cellular_component	nucleus
w	0005654	cellular_component	nucleoplasm
w	0005681	cellular_component	spliceosomal complex
w	0006397	biological_process	mRNA processing
w	0008380	biological_process	RNA splicing
w	0016604	cellular_component	nuclear body
w	0071013	cellular_component	catalytic step 2 spliceosome
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0003723	molecular_function	RNA binding
W	0003729	molecular_function	mRNA binding
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005681	cellular_component	spliceosomal complex
W	0006397	biological_process	mRNA processing
W	0008380	biological_process	RNA splicing
W	0016607	cellular_component	nuclear speck
W	0071007	cellular_component	U2-type catalytic step 2 spliceosome
W	0071013	cellular_component	catalytic step 2 spliceosome
W	1990403	biological_process	embryonic brain development
x	0000398	biological_process	mRNA splicing, via spliceosome
x	0000775	cellular_component	chromosome, centromeric region
x	0003723	molecular_function	RNA binding
x	0005515	molecular_function	protein binding
x	0005634	cellular_component	nucleus
x	0005654	cellular_component	nucleoplasm
x	0005681	cellular_component	spliceosomal complex
x	0005694	cellular_component	chromosome
x	0005829	cellular_component	cytosol
x	0006397	biological_process	mRNA processing
x	0007059	biological_process	chromosome segregation
x	0008380	biological_process	RNA splicing
x	0030623	molecular_function	U5 snRNA binding
x	0045292	biological_process	mRNA cis splicing, via spliceosome
x	0060629	biological_process	regulation of homologous chromosome segregation
X	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
X	0003677	molecular_function	DNA binding
X	0003684	molecular_function	damaged DNA binding
X	0003723	molecular_function	RNA binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005739	cellular_component	mitochondrion
X	0005794	cellular_component	Golgi apparatus
X	0005829	cellular_component	cytosol
X	0005886	cellular_component	plasma membrane
X	0006260	biological_process	DNA replication
X	0006397	biological_process	mRNA processing
X	0008380	biological_process	RNA splicing
X	0016485	biological_process	protein processing
X	0016567	biological_process	protein ubiquitination
X	0016607	cellular_component	nuclear speck
X	0030515	molecular_function	snoRNA binding
X	0031571	biological_process	mitotic G1 DNA damage checkpoint signaling
X	0034644	biological_process	cellular response to UV
X	0042254	biological_process	ribosome biogenesis
X	0045292	biological_process	mRNA cis splicing, via spliceosome
X	0051301	biological_process	cell division
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0000413	biological_process	protein peptidyl-prolyl isomerization
y	0003723	molecular_function	RNA binding
y	0003729	molecular_function	mRNA binding
y	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
y	0005515	molecular_function	protein binding
y	0005576	cellular_component	extracellular region
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005681	cellular_component	spliceosomal complex
y	0005737	cellular_component	cytoplasm
y	0005829	cellular_component	cytosol
y	0006355	biological_process	regulation of DNA-templated transcription
y	0006397	biological_process	mRNA processing
y	0006457	biological_process	protein folding
y	0008143	molecular_function	poly(A) binding
y	0008380	biological_process	RNA splicing
y	0016018	molecular_function	cyclosporin A binding
y	0016607	cellular_component	nuclear speck
y	0034774	cellular_component	secretory granule lumen
y	0043231	cellular_component	intracellular membrane-bounded organelle
y	0045070	biological_process	positive regulation of viral genome replication
y	0071007	cellular_component	U2-type catalytic step 2 spliceosome
y	0071013	cellular_component	catalytic step 2 spliceosome
y	1904813	cellular_component	ficolin-1-rich granule lumen
z	0000122	biological_process	negative regulation of transcription by RNA polymerase II
z	0003682	molecular_function	chromatin binding
z	0003723	molecular_function	RNA binding
z	0005515	molecular_function	protein binding
z	0005634	cellular_component	nucleus
z	0005654	cellular_component	nucleoplasm
z	0005829	cellular_component	cytosol
z	0007219	biological_process	Notch signaling pathway
z	0030097	biological_process	hemopoiesis
z	0030851	biological_process	granulocyte differentiation
z	0031490	molecular_function	chromatin DNA binding
z	0033077	biological_process	T cell differentiation in thymus
z	0035019	biological_process	somatic stem cell population maintenance
z	0045892	biological_process	negative regulation of DNA-templated transcription
z	0046638	biological_process	positive regulation of alpha-beta T cell differentiation
z	0071425	biological_process	hematopoietic stem cell proliferation
Z	0005515	molecular_function	protein binding
Z	0005654	cellular_component	nucleoplasm
Z	0005684	cellular_component	U2-type spliceosomal complex
Z	0071014	cellular_component	post-mRNA release spliceosomal complex

Functional Information from PROSITE/UniProt

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADEmL

Chain	Residue	Details
7	VAL185-LEU193

---

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. FkgSsFHRIIpqFMcQGG

Chain	Residue	Details
y	PHE184-GLY201
S	TYR48-GLY65

---

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. VSKGQRVKVKVLSFT

Chain	Residue	Details
V	VAL313-THR327

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LASAgfDrLILLWNV

Chain	Residue	Details
E	LEU81-VAL95
E	LEU124-SER138
E	VAL167-ILE181
E	ILE208-LEU222
E	ILE300-THR314
T	LEU303-VAL317
T	ILE345-LEU359
W	LEU304-VAL318
q	LEU407-LEU421

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. AiIMLDEAHE

Chain	Residue	Details
V	ALA680-GLU689

---

site_id	PS00997
Number of Residues	23
Details	G10_1 G10 protein signature 1. LCClRCiqtrDtNfgtnCiCRVP

Chain	Residue	Details
N	LEU100-PRO122

---

site_id	PS00998
Number of Residues	10
Details	G10_2 G10 protein signature 2. CtHCGCRGCS

Chain	Residue	Details
N	CYS134-SER143

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:16923391, ECO:0000269|PubMed:16931718, ECO:0000269|PubMed:19033377, ECO:0000269|PubMed:20479275, ECO:0007744|PDB:2HYI, ECO:0007744|PDB:2J0Q, ECO:0007744|PDB:2J0S, ECO:0007744|PDB:2XB2, ECO:0007744|PDB:3EX7

Chain	Residue	Details
7	LYS60
7	GLN65
7	GLY85
7	ASP342
7	ARG367
S	LYS125

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
7	MET1
q	LYS261
r	LYS122
r	LYS261
s	LYS122
s	LYS261
t	LYS122
t	LYS261

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylalanine; in Eukaryotic initiation factor 4A-III, N-terminally processed => ECO:0000269|Ref.8, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378

Chain	Residue	Details
7	ALA2
q	LYS244
r	LYS179
r	LYS244
s	LYS179
s	LYS244
t	LYS179
t	LYS244

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P60842

Chain	Residue	Details
7	SER10
o	SER255
d	LYS8
k	LYS6
k	LYS8

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
7	SER12
SR	SER1460
SR	SER1462
SR	SER1482
SR	SER1483
SR	SER1501
SR	SER1621
SR	SER1893
SR	SER2343
SR	SER2394
SR	SER2453
SR	SER222
z	LYS305
SR	SER484
SR	SER486
SR	SER875
SR	SER1336
SR	SER1368
SR	SER1421

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P60842

Chain	Residue	Details
7	LYS124
R	LYS416
R	LYS441
R	LYS452
o	LYS221
U	LYS408
R	LYS141
R	LYS158
R	LYS258
R	LYS286
R	LYS339
R	LYS344

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
7	THR163
SR	SER994
SR	SER1014

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P60843

Chain	Residue	Details
7	LYS198
SR	SER1179
SR	SER2581

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
7	LYS296
7	LYS321
SR	SER1152

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733

Chain	Residue	Details
7	LYS19
SR	SER857
SR	SER952
SR	SER1318
SR	SER1401
SR	SER2100

---

site_id	SWS_FT_FI11
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
SR	SER323
7	LYS314
7	LYS382

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P60842

Chain	Residue	Details
7	LYS152
7	LYS374

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
SR	SER357
SR	SER358
SR	SER846
SR	SER1214

---

site_id	SWS_FT_FI14
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
SR	THR359
SR	THR1106
SR	THR2381

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR367
L	LYS487

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER377

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	THR383
SR	THR384

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER387

---

site_id	SWS_FT_FI19
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER395
SR	SER935
SR	SER1311

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER398

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER404
SR	SER408

---

site_id	SWS_FT_FI22
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER424
SR	SER1124
SR	SER2702

---

site_id	SWS_FT_FI23
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER435
SR	SER2121
SR	SER2675
SR	SER2677
SR	SER780
SR	SER864
SR	SER1064
SR	SER1112
SR	SER1537
SR	SER1539
SR	SER1541
SR	SER1876

---

site_id	SWS_FT_FI24
Number of Residues	24
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER436
SR	SER704
SR	SER706
SR	SER992
SR	SER1198
SR	SER1227
SR	SER1254
SR	SER1257
SR	SER1258
SR	SER2018
SR	SER2030
SR	SER437
SR	SER2042
SR	SER2310
SR	SER2368
SR	SER2376
SR	SER2740
SR	SER506
SR	SER508
SR	SER510
SR	SER534
SR	SER536
SR	SER543
SR	SER702

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER440
SR	SER1188

---

site_id	SWS_FT_FI26
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER778
SR	SER2123
SR	SER2398
SR	SER2407
SR	SER2692

---

site_id	SWS_FT_FI27
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692

Chain	Residue	Details
SR	SER783
SR	SER1522
SR	SER1970

---

site_id	SWS_FT_FI28
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8BTI8

Chain	Residue	Details
SR	SER854
SR	SER1423
SR	SER1616
SR	SER1620
SR	SER1024
SR	SER1042
SR	SER1266
SR	SER1270
SR	SER1271
SR	SER1348
SR	SER1383
SR	SER1384

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q8BTI8

Chain	Residue	Details
SR	THR856

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	THR866

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:20068231

Chain	Residue	Details
SR	SER871

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER876

---

site_id	SWS_FT_FI33
Number of Residues	24
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
SR	SER908
SR	SER1582
SR	SER1598
SR	SER1600
SR	SER1601
SR	SER1658
SR	SER1727
SR	SER1729
SR	SER1731
SR	SER1732
SR	SER1818
SR	SER1129
SR	SER1822
SR	SER1884
SR	SER2090
SR	SER2415
SR	SER2429
SR	SER1424
SR	SER1517
SR	SER1519
SR	SER1521
SR	SER1577
SR	SER1579
SR	SER1581

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER950

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER954

---

site_id	SWS_FT_FI36
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
SR	SER957
SR	SER1946
SR	SER1958
SR	SER2118
SR	SER968
SR	SER970
SR	SER972
SR	SER1032
SR	SER1451
SR	SER1691
SR	SER1693
SR	SER1923

---

site_id	SWS_FT_FI37
Number of Residues	18
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
SR	SER973
SR	SER1975
SR	SER1984
SR	SER1987
SR	SER1996
SR	SER1999
SR	SER2008
SR	SER2011
SR	SER2664
SR	SER2706
SR	SER1497
SR	SER1502
SR	SER1762
SR	SER1764
SR	SER1890
SR	SER1916
SR	SER1919
SR	SER1972

---

site_id	SWS_FT_FI38
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
SR	SER974
SR	SER1415
SR	SER1925
SR	SER1948
SR	SER1960

---

site_id	SWS_FT_FI39
Number of Residues	7
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
SR	THR977
SR	THR1043
SR	THR1931
SR	THR1954
SR	THR1966
SR	THR1978
SR	THR2092

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	THR983

---

site_id	SWS_FT_FI41
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	TYR996
SR	TYR1049

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	THR1003

---

site_id	SWS_FT_FI43
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER1010

---

site_id	SWS_FT_FI44
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
SR	SER1028
SR	SER2690

---

site_id	SWS_FT_FI45
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER1069
SR	SER1444
SR	SER1542
SR	SER1552
SR	SER1694
SR	SER1878
SR	SER2412

---

site_id	SWS_FT_FI46
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648

Chain	Residue	Details
SR	SER1072
SR	SER1073

---

site_id	SWS_FT_FI47
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
SR	SER1099
SR	SER1101

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332

Chain	Residue	Details
SR	SER1102

---

site_id	SWS_FT_FI49
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER1103
SR	SER1404
SR	SER2132

---

site_id	SWS_FT_FI50
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER1122
SR	SER1857
SR	SER2335

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER1132

---

site_id	SWS_FT_FI52
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR1208
SR	THR1880

---

site_id	SWS_FT_FI53
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER1219

---

site_id	SWS_FT_FI54
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER1320
SR	SER1387

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER1326

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER1329

---

site_id	SWS_FT_FI57
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER1382

---

site_id	SWS_FT_FI58
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER1403

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR1413

---

site_id	SWS_FT_FI60
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR1434

---

site_id	SWS_FT_FI61
Number of Residues	5
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
SR	THR1453
SR	THR1472
SR	THR1511
SR	THR1698
SR	THR2144

---

site_id	SWS_FT_FI62
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER1458
SR	SER1648
SR	SER2020
SR	SER2032
SR	SER2067

---

site_id	SWS_FT_FI63
Number of Residues	9
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER1463
SR	SER1499
SR	SER1854
SR	SER2044
SR	SER2046
SR	SER2071
SR	SER2426
SR	SER2684
SR	SER2688

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR1492

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17924679, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR1531

---

site_id	SWS_FT_FI66
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
SR	THR1927
SR	THR1950
SR	THR1962

---

site_id	SWS_FT_FI67
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR2022
SR	THR2034

---

site_id	SWS_FT_FI68
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR2069

---

site_id	SWS_FT_FI69
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER2102

---

site_id	SWS_FT_FI70
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR2104

---

site_id	SWS_FT_FI71
Number of Residues	7
Details	MOD_RES: Omega-N-methylarginine => ECO:0007744|PubMed:24129315

Chain	Residue	Details
SR	ARG2194
SR	ARG2207
SR	ARG2231
SR	ARG2246
SR	ARG2274
SR	ARG2288
SR	ARG2342

---

site_id	SWS_FT_FI72
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER2272

---

site_id	SWS_FT_FI73
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR2289

---

site_id	SWS_FT_FI74
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243

Chain	Residue	Details
SR	THR2291

---

site_id	SWS_FT_FI75
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
SR	THR2302

---

site_id	SWS_FT_FI76
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR2316

---

site_id	SWS_FT_FI77
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR2329
SR	THR2409

---

site_id	SWS_FT_FI78
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	SER2382

---

site_id	SWS_FT_FI79
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine; alternate => ECO:0007744|PubMed:24129315

Chain	Residue	Details
SR	ARG2384

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site_id	SWS_FT_FI80
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER2449

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site_id	SWS_FT_FI81
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569

Chain	Residue	Details
SR	THR2583

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site_id	SWS_FT_FI82
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	THR2599
SR	THR2738

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site_id	SWS_FT_FI83
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
SR	SER2694

---

site_id	SWS_FT_FI84
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
SR	LYS108
SR	LYS130
SR	LYS2587

---