9FJR
Cryo-EM structure of Mycobacterium tuberculosis sigma-B RNA polymerase bound to -10 promoter element ssDNA oligo - sigma-B docked conformation
Functional Information from PROSITE/UniProt
| site_id | PS00715 |
| Number of Residues | 14 |
| Details | SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnLGLIrAM |
| Chain | Residue | Details |
| f | ASP114-MET127 |
| site_id | PS00716 |
| Number of Residues | 27 |
| Details | SIGMA70_2 Sigma-70 factors family signature 2. TldQIGklfgLSrerVrQIErdvMskL |
| Chain | Residue | Details |
| f | THR283-LEU309 |
| site_id | PS00867 |
| Number of Residues | 8 |
| Details | CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LLEANLRL |
| Chain | Residue | Details |
| f | LEU90-LEU97 |
| site_id | PS01166 |
| Number of Residues | 13 |
| Details | RNA_POL_BETA RNA polymerases beta chain signature. GdKLAGrHGNKGV |
| Chain | Residue | Details |
| c | GLY882-VAL894 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | DNA_BIND: H-T-H motif => ECO:0000250 |
| Chain | Residue | Details |
| f | LEU284-ARG303 | |
| d | CYS975 | |
| d | CYS978 | |
| d | CYS62 | |
| d | CYS75 | |
| d | CYS78 | |
| d | ASP535 | |
| d | ASP537 | |
| d | ASP539 | |
| d | CYS891 | |
| d | CYS968 |
