9FJM
Cryo-EM structure of the phalloidin-bound pointed end of the actin filament.
Functional Information from PROSITE/UniProt
| site_id | PS00406 |
| Number of Residues | 11 |
| Details | ACTINS_1 Actins signature 1. YVGDEAQs.KRG |
| Chain | Residue | Details |
| A | TYR53-GLY63 |
| site_id | PS00432 |
| Number of Residues | 9 |
| Details | ACTINS_2 Actins signature 2. WISKqEYDE |
| Chain | Residue | Details |
| A | TRP356-GLU364 |
| site_id | PS01132 |
| Number of Residues | 13 |
| Details | ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR |
| Chain | Residue | Details |
| A | LEU104-ARG116 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: N-acetylaspartate; in Actin, cytoplasmic 1, N-terminally processed => ECO:0000269|PubMed:29581253, ECO:0000269|PubMed:30028079, ECO:0000269|Ref.8, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712 |
| Chain | Residue | Details |
| A | ASP2 | |
| B | ASP2 | |
| C | ASP2 | |
| D | ASP2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | MOD_RES: Methionine (R)-sulfoxide => ECO:0000269|PubMed:29343822 |
| Chain | Residue | Details |
| A | MET44 | |
| A | MET47 | |
| B | MET44 | |
| B | MET47 | |
| C | MET44 | |
| C | MET47 | |
| D | MET44 | |
| D | MET47 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:30526847, ECO:0000269|PubMed:30626964, ECO:0000269|PubMed:30785395, ECO:0000269|PubMed:31388018, ECO:0000269|PubMed:32503840 |
| Chain | Residue | Details |
| A | HIC73 | |
| B | HIC73 | |
| C | HIC73 | |
| D | HIC73 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-methyllysine => ECO:0000269|PubMed:23673617 |
| Chain | Residue | Details |
| A | LYS84 | |
| B | LYS84 | |
| C | LYS84 | |
| D | LYS84 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CROSSLNK: (Microbial infection) Isoglutamyl lysine isopeptide (Lys-Glu) (interchain with E-270); by Vibrio toxins RtxA and VgrG1 => ECO:0000305|PubMed:19015515 |
| Chain | Residue | Details |
| A | LYS50 | |
| B | LYS50 | |
| C | LYS50 | |
| D | LYS50 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | CROSSLNK: (Microbial infection) Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-50); by Vibrio toxins RtxA and VgrG1 => ECO:0000305|PubMed:19015515 |
| Chain | Residue | Details |
| A | GLU270 | |
| B | GLU270 | |
| C | GLU270 | |
| D | GLU270 |
